Application of micro-ct assessment of 3-d bone microstructure in preclinical and clinical studies

Journal of Bone and Mineral Metabolism

Volumn 23, Issue SUPPL. 1, 2005, Pages 122-131

  Jiang, Yebin ^a   Zhao, Jenny ^a   Liao, Er Yuan ^b   Dai, Ru Chun ^b   Wu, Xian Ping ^b   Genant, Harry K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

3 D microstructure; Estrogen; Human; Mouse; Osteoporosis; PTH; Rat

Indexed keywords

ANIMAL; ARTICLE; BONE; BONE DENSITY; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; MALE; MICRORADIOGRAPHY; MOUSE; MOUSE MUTANT; PATHOLOGY; POSTMENOPAUSE OSTEOPOROSIS; RADIOGRAPHY; RAT; THREE DIMENSIONAL IMAGING;

ANIMALS; BONE AND BONES; BONE DENSITY; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; MICE; MICE, KNOCKOUT; MICRORADIOGRAPHY; OSTEOPOROSIS, POSTMENOPAUSAL; RATS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 23844490526     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03026336     Document Type: Review

References (49)

1. Jiang Y, Zhao J, Genant HK (2002) Macro and micro imaging of bone architecture. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of Bone Biology, 2nd edn. Academic. San Diego, pp 1599-1623
2. Y Jiang J Zhao P Geusens EY Liao P Adriaensens J Gelan M Azria S Boonen F Caulin JA Lynch Ouyang X Xiaolong HK Genant 2005 Femoral neck trabecular microstructure in ovariectomized ewes treated with calcitonin: MRI microscopic evaluation J Bone Miner Res 20 125 130
3. LA Feldkamp SA Goldstein AM Parfift G Jesioil M Kleerekoper 1989 The direct examination of three-dimensional bone architecture in vitro by computed tomography J Bone Miner Res 4 3 11
4. JL Kuhn SA Goldstein LA Feldkamp RW Goulet G Jesion 1990 Evaluation of a microcomputed tomography system to study trabecular bone structure J Orthop Res 8 833 842
5. AM Parfitt C Matthews A Villanueva 1983 Relationships between surface, volume and thickness of iliac trabecular bone in aging and in osteoporosis J Clin Invest 72 1396 1409
6. F Guilak 1994 Volume and surface area of viable chondrocytes in situ using geometric modeling of serial confocal sections J Microsc 173 245 256
7. T Hildebrand P Ruegsegger 1997 A new method for the model independent assessment of thickness in three-dimensional images J Microsc 185 67 75
8. A Odgaard HJG Gundersen 1993 Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstruction Bone 14 173 182
9. Engelke K, Kalender W (1998) Beyond bone densitometry: assessment of bone architecture by x-ray computed tomography at various levels of resolution. In: Genant HK, Guglielmi G, Jergas M (eds) Bone Densitometry and Osteoporosis. Springer, Berlin, pp 417-447
10. Y Jiang J Zhao P Augat X Ouyang Y Lu S Majumdar HK Genant 1998 Trabecular bone mineral and calculated structure of human bone specimens scanned by peripheral quantitative computed tomography: relation to biomechanical properties J Bone Miner Res 13 1783 1790
11. Y Jiang J Zhao BH Mitlak O Wang HK Genant EF Eriksen 2003 Recombinant human parathyroid hormone (1-34) (teriparatide) improves both cortical and cancellous bone structure J Bone Miner Res 18 1932 1941
12. JH Kinney NE Lane DL Haupt 1995 In vivo, three-dimensional microscopy of trabecular bone J Bone Miner Res 10 264 270
13. RW Goulet SA Goldstein MJ Ciarelli JL Kuhn MB Brown LA Feldkamp 1994 The relationship between the structural and orthogonal compressive properties of trabecular bone J Biomech 27 375 389
14. K Engelke SM Song CC Glüer HK Genant 1996 A digital model of trabecular bone J Bone Miner Res 11 480 489
15. R Miiller P Rüegsegger 1996 Analysis of mechanical properties of cancellous bone under conditions of simulated bone atrophy J Biomech 29 1053 1060
16. H Sugita M Oka J Toguchida T Nakamura T Ueo T Hayami 1999 Anisotropy of osteoporotic cancellous bone Bone 24 513 516
17. S Majumdar M Kothari P Augat DC Newitt JC Lin T Lang Y Lu HK Genant 1998 High-resolution magnetic resonance imaging: three-dimensional bone architecture and biomechanical properties Bone 22 445 454
18. K Engelke W Graeff L Meiss M Hahn G Delling 1993 High spatial resolution imaging of bone mineral using computed microtomography. Comparison with microradiography and undecalcified histologic sections Invest Radiol 28 341 349
19. WG Geraets der Stelt PF Van P Lips PJM Elders FC Van Ginkel EH Burger 1997 Orientation of the trabecular pattern of the distal radius around the menopause J Biomech 30 363 370
20. Engelke K, Dix W, Graeff W (1991) Quantitative microtomography and microradiography of bones using synchrotronradiation. Presented at 8th International Workshop on Bone Densitometry, Bad Reichenhall, Germany
21. P Rüegsegger B Koller R Muller 1996 A microtomographic system for the nondestructive evaluation of bone architecture Calcif Tissue Int 58 24 29
22. T Hildebrand P Rüegsegger 1997 Quantification of bone microarchitecture with the structure model index Comp Methods Biomech Biomed Eng 1 15 23
23. Y Jiang J Zhao RR Recker MW Draper HK Genant 2000 Longitudinal changes between premenopausal and postmenopausal in three-dimensional trabecular microstructural characteristics of human iliac crest bone biopsies J Bone Miner Res 15 S184 S184
24. L Mosekilde 1993 Vertebral structure and strength in vivo and in vitro Calcif Tissue Int 53 S121 S125
25. Y Jiang J Zhao EF Eriksen HK Genant 2003 Reproducibility of micro-CT quantification of 3D microarchitecture of the trabecular and cortical bone in the iliac crest of postmenopausal osteoporotic women and their treatment with teriparatide [rhPTH(l-34)] RSNA 2003 571 571
26. J Zhao Y Jiang S Vedi JE Compston HK Genantt 2002 Longitudinal changes in three-dimensional trabecular microarchitecture of paired iliac crest bone biopsies before and after estrogen replacement therapy in postmenopausal women J Bone Miner Res 17 S208 S208
27. B Borah EL Ritman TE Dufresne S Liu PA Chmielewski SM Jorgensen DA Reyes RT Turner RJ Phipps MD Manhart JD Sibonga 2004 Five year residronate therapy normalizes mineralization: synchrotron radiation μCT study of sequential triple biopsies J Bone Miner Res 19 S308 S308
28. DW Dempster F Cosman E Kurland R Muller J Nieves L Woelfert E Shane K Plavetic J Bilezikian R Lindsay 2000 Two- and three-dimensional structural analysis of paired biopsies from osteoporotic patients before and after treatment with parathyroid hormone J Bone Miner Res 15 S194 S194
29. Y Jiang J Zhao HK Genant J Dequeker P Geusens 1997 Longterm changes in bone mineral and biomechanical properties of vertebrae and femur in aging, dietary calcium restricted and/or estrogen-deprived/-replaced rats J Bone Miner Res 19 820 831
30. Y Jiang J Zhao S Prevrhal HK Genant 1999 Three-dimensional trabecular microstructure, bone mineral density, and biomechanical properties of the vertebral body of ovariectomized rats with estrogen replacement therapy J Bone Miner Res 14 S1 S534 S534
31. J Zhao Y Jiang HK Genant 2000 Three-dimensional trabecular microstructure and biomechanical properties and their relationship in different bone quality models Radiology 217 411 411
32. J Zhao Y Jiang S Prevrhal HK Genant 2000 Effects of low dose long-term sodium fluoride on three-dimensional trabecular microstructure, bone mineral, and biomechanical properties of rat vertebral body J Bone Miner Res 15 816 816
33. CH Turner YF Hsieh R Muller ML Bouxsein CJ Rosen ME McCrann LR Donahue WG Beamer 2001 Variation in bone biomechanical properties, microstructure, and density in BXH recombinant inbred mice J Bone Miner Res 16 206 213
34. B He Y Jiang J Zhao HK Genant D Goltzman AC Karaplis 2000 Quantitative assessment of three-dimensional trabecular bone microstructure in PTHrP wild type and heterozygous-null mice using micro computed tomography J Bone Miner Res 15 S186 S186
35. S Takeshita N Namba J Zhao Y Jiang HK Genant MJ Silva MD Brodt CD Helgason J Kalesnikoff MJ Rauh RK Humphries G Krystal SL Teitelbaum FP Ross 2002 SHIP-deficient mice are severely osteoporotic due to increased numbers of hyperresorptive osteoclasts Nat Med 8 943 949
36. MO Bergo B Gavino J Ross WK Schmidt C Hong LV Kendall A Mohr M Meta H Genant Y Jiang ER Wisner N Van Bruggen RA Carano S Michaelis SM Griffey SG Young 2002 Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect Proc Natl Acad Sci USA 99 13049 13054
37. D Chen M Qiao B Story M Zhao Y Jiang J Zhao J Feng Y Xie S Huang A Roberts G Karsenty G Mundy 2003 BMP signaling through the Smad1 pathway is required for normal postnatal bone formation J Bone Miner Res 18 S6 S6
38. J Zhao Y Jiang V Shen S Bain HK Genant 2000 μGT and pQCT assessments of a murine model of postmenopausal osteoporosis and estrogen therapy Osteoporosis Int 11 S3 S11 S11
39. Van Rietbergen B (2003) Finite element modeling. In: Abstract Book of the 1st μCT User Workshop, Philadelphia, PA
40. Han B, Brodie T, Shen Y, Triantafillou J, Scates P, Willams J (2001) Subchondral bone changes in an ACLT model of osteoarthritis in the dog. In: Proceedings, International Symposim on Bone Biotechnology and Histotechnology, Phoenix, AZ, March 7-10, 2001, p 31
41. -4 energy resolution Bone Miner 25 25 38
42. Smith CB, Silver MD (1994) Comparison between single slice CT and volume CT. In: Czichos HCH, Schnitger D (eds) International Symposium on Computerized Tomography for Industrial Applications, Bundesministerium des Innern, Bundesanstalt fur Materialforschung und-prufung, Berlin, Germany, 8-10 June, 1994
43. Holdsworth DW, Robarts JP, Thornton MM (2001) Validation of cone-beam reconstruction for bone micro-CT. In: Proceedings, International Symposim on Bone Biotechnology and Histotechnology, Phoenix, AZ, March 7-10, 2001, p 33
44. L Grodzins 1983 Optimum energy for x-ray transmission tomography of small samples Nucl Instrum Methods 206 541 543
45. Peyrin F, Salome M, Cloetens P, Ludwig W, Ritman, Ruegsegger P, Laval-Jeantet AM, Baruchel J (1998) What do micro-CT examinations reveal at various resolutions: a study of the same trabecular bone samples at the 14, 7, and 2 micron level. Presented at the Symposium on Bone Architecture and the Competence of Bone, Ittingen, Switzerland
46. NE Lane JM Thompson GJ Strewler JH Kinney 1995 Intermittent treatment with human parathyroid hormone (hPTH[l-34]) increased trabecular bone volume but not connectivity in osteopenic rats J Bone Miner Res 10 1470 1477
47. NE Lane D Haupt DB Kimmel G Modin JH Kinney 1999 Early estrogen replacement therapy reverses the rapid loss of trabecular bone volume and prevents further deterioration of connectivity in the rat J Bone Miner Res 14 206 214
48. JH Kinney DL Haupt M Balooch AJ Ladd JT Ryaby NE Lane 2000 Three-dimensional morphometry of the L6 vertebra in the ovariectomized rat model of osteoporosis: biomechanical implications J Bone Miner Res 15 1981 1991
49. Flynn MJ, Seifert HA, Irving TC, Lai B (2001) Measurement of bone mineralization in whole trabeculae using 3D x-ray microtomography. In: Proceeding of International Symposim on Bone Biotechnology and Histotechnology. Phoenix, March 7-10, 2001, p 28