Continuous inhalation of carbon monoxide induces right ventricle ischemia and dysfunction in rats with hypoxic pulmonary hypertension

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 2, 2007, Pages

  Gautier, Mathieu ^a   Antier, Daniel ^a   Bonnet, Pierre ^a   Le Net, Jean Loic ^b   Hanton, Gilles ^b   Eder, Veronique ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b PFIZER INC   (United States)

Author keywords

Right ventricle perfusion; Right ventricle remodeling

Indexed keywords

CARBON MONOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON MONOXIDE INTOXICATION; ELECTROCARDIOGRAM; FIBROSIS; HEART CATHETERIZATION; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PERFUSION; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE FUNCTION; HISTOLOGY; HYPOBARISM; HYPOXIA; MALE; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; SYSTOLIC BLOOD PRESSURE; WISTAR RAT;

ADMINISTRATION, INHALATION; ANIMALS; ANOXIA; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARBON MONOXIDE; CARBOXYHEMOGLOBIN; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; FIBROSIS; HEART CATHETERIZATION; HEART VENTRICLES; HEMATOCRIT; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; LASER-DOPPLER FLOWMETRY; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; PULMONARY ARTERY; RATS; RATS, WISTAR; VENTRICULAR FUNCTION, LEFT; VENTRICULAR FUNCTION, RIGHT; VENTRICULAR PRESSURE; VENTRICULAR REMODELING;

EID: 34547862429     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01040.2006     Document Type: Article

References (28)

1. Boissiere J, Gautier M, Machet MC, Hanton G, Bonnet P, Eder V. Doppler tissue imaging in assessment of pulmonary hypertension-induced right ventricle dysfunction. Am J Physiol Heart Circ Physiol 289: H2450-H2455, 2005.
2. Buckberg GD, Luck JC, Payne DB, Hoffman JI, Archie JP, Fixler DE. Some sources of error in measuring regional blood flow with radioactive microspheres. J Appl Physiol 31: 598-604, 1971.
3. Ca channels. Cardiovasc Res 65: 751-761, 2005.
4. Goldberg MS, Bailar JC 3rd, Burnett RT, Brook JR, Tamblyn R, Bonvalot Y, Ernst P, Flegel KM, Singh RK, Valois MF. Identifying subgroups of the general population that may be susceptible to short-term increases in particulate air pollution: a time-series study in Montreal, Quebec. Res Rep Health Eff Inst 97: 7-113; 115-120, 2000.
5. Hart CL, Davey Smith G, Hole D, Hawthorne V. Carboxyhaemoglobin level, smoking habit, and mortality in 25 years in the Renfrew/Paisley prospective cohort study. Heart 92: 321-324, 2006.
6. Huang LE, Willmore WG, Gu J, Goldberg MA, Bunn HF. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling. J Biol Chem 274: 9038-9044, 1999.
7. Iltis I, Kober F, Dalmasso C, Lan C, Cozzone PJ, Bernard M. In vivo assessment of myocardial blood flow in rat heart using magnetic resonance imaging: effect of anesthesia. J Magn Reson Imaging 22: 242-247, 2005.
8. Kolarova JD, Ayoub IM, Gazmuri RJ. Cariporide enables hemodynamically more effective chest compression by leftward shift of its flow-depth relationship. Am J Physiol Heart Circ Physiol 288: H2904-H2911, 2005.
9. Kourembanas S, Morita T, Liu Y, Christou H. Mechanisms by which oxygen regulates gene expression and cell-cell interaction in the vasculature. Kidney Int 51: 438-443, 1997.
10. Loennechen JP, Beisvag V, Arbo I, Waldum HL, Sandvik AK, Knardahl S, Ellingsen O. Chronic carbon monoxide exposure in vivo induces myocardial endothelin-1 expression and hypertrophy in rat. Pharmacol Toxicol 85: 192-197, 1999.
11. Melin A, Obert P, Rebocho M, Bonnet P. Cardiac morphology and function following long-term exposure to carbon monoxide at high altitude in rats. J Toxicol Environ Health A 65: 1981-1998, 2002.
12. Murohara T, Witzenbichler B, Spyridopoulos I, Asahara T, Ding B, Sullivan A, Losordo DW, Isner JM. Role of endothelial nitric oxide synthase in endothelial cell migration. Arterioscler Thromb Vasc Biol 19: 1156-1161, 1999.
13. Myers I, Maynard RL. Polluted air - outdoors and indoors. Occup Med (Lond) 55: 432-438, 2005.
14. Ndisang JF, Tabien HE, Wang R. Carbon monoxide and hypertension. J Hypertens 22: 1057-1074, 2004.
15. Partovian C, Adnot S, Eddahibi S, Teiger E, Levame M, Dreyfus P, Raffestin B, Frelin C. Heart and lung VEGF mRNA expression in rats with monocrotaline- or hypoxia-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol 275: H1948-H1956, 1998.
16. Penney DG, Davidson SB, Gargulinski RB, Caldwell-Ayre TM. Heart and lung hypertrophy, changes in blood volume, hematocrit and plasma renin activity in rats chronically exposed to increasing carbon monoxide concentrations. J Appl Toxicol 8: 171-178, 1988.
17. Raub JA, Mathieu-Nolf M, Hampson NB, Thom SR. Carbon monoxide poisoning - a public health perspective. Toxicology 145: 1-14, 2000.
18. Rhodes J. Comparative physiology of hypoxic pulmonary hypertension: historical clues from brisket disease. J Appl Physiol 98: 1092-1100, 2005.
19. Routledge HC, Ayres JG. Air pollution and the heart. Occup Med (Lond) 55: 439-447, 2005.
20. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58: 1072-1083, 1978.
21. Savourey G, Launay JC, Besnard Y, Guinet A, Bourrilhon C, Cabane D, Martin S, Caravel JP, Pequignot JM, Cottet-Emard JM. Control of erythropoiesis after high altitude acclimatization. Eur J Appl Physiol 93: 47-56, 2004.
22. Stern FB, Halperin WE, Hornung RW, Ringenburg VL, McCammon CS. Heart disease mortality among bridge and tunnel officers exposed to carbon monoxide. Am J Epidemiol 128: 1276-1288, 1988.
23. Thom SR, Fisher D, Xu YA, Notarfrancesco K, Ischiropoulos H. Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide. Proc Natl Acad Sci USA 97: 1305-1310, 2000.
24. Thorup C, Jones CL, Gross SS, Moore LC, Goligorsky MS. Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. Am J Physiol Renal Physiol 277: F882-F889, 1999.
25. Townsend CL, Maynard RL. Effects on health of prolonged exposure to low concentrations of carbon monoxide. Occup Environ Med 59: 708-711, 2002.
26. Wang R. The gasotransmitter role of hydrogen sulfide. Antioxid Redox Signal 5: 493-501, 2003.
27. Wang R, Wang Z, Wu L. Carbon monoxide-induced vasorelaxation and the underlying mechanisms. Br J Pharmacol 121: 927-934, 1997.
28. World Health Organization. Carbon monoxide. In: International Program on Chemical Safety Environmental Health Criteria 213 (2nd ed.). Geneva: World Health Organization, 1999.