Diethylnitrosamine initiation does not alter clofibric acid-induced hepatocarcinogenesis in the rat

Toxicological Sciences

Volumn 99, Issue 1, 2007, Pages 58-69

  Michel, Cecile ^a   Desdouets, Chantal ^b   Slaoui, Mohamed ^a   Isaacs, Kevin Robert ^c   Roberts, Ruth Angela ^d   Boitier, Eric ^a  

^a SANOFI   (France)

^b INSERM   (France)

^c Safety Assessment ^*  (United Kingdom)

^d ASTRAZENECA   (United Kingdom)

Author keywords

Clofibrate; Diethylnitrosamine; Hepatocarcinogenesis; Initiation; Peroxisome proliferators; Promotion; Toxicogenomics

Indexed keywords

CLOFIBRIC ACID; DIETHYLNITROSAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CARCINOGENICITY; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; IMMUNOPATHOLOGY; LIVER CANCER; LIVER CARCINOGENESIS; MALE; MOLECULAR DYNAMICS; NONHUMAN; RAT; SINGLE DRUG DOSE; TOXICOGENETICS;

ALKYLATING AGENTS; ANIMALS; ANTICHOLESTEREMIC AGENTS; CARCINOGENS; CLOFIBRIC ACID; COCARCINOGENESIS; DIETHYLNITROSAMINE; DRUG INTERACTIONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; RATS; TOXICOGENETICS;

RATTUS; RODENTIA;

EID: 34547859238     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm168     Document Type: Article

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