The pig as the donor of pancreatic islets for men

Veterinary Research Communications

Volumn 31, Issue SUPPL. 1, 2007, Pages 27-33

  Trucco, M ^a,b   Casu, A ^a,b   Bottino, R ^a,b  

^a MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Homologous recombination; Pig; Type 1 diabetes; Xenotransplantation

Indexed keywords

GENOMIC DNA; IMMUNOSUPPRESSIVE AGENT; INSULIN; MESSENGER RNA;

ALLOTRANSPLANTATION; ARTICLE; CADAVER DONOR; DIABETES MELLITUS; DNA SEQUENCE; GENE SEQUENCE; GENE TARGETING; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KNOCKOUT GENE; LIFESTYLE; MOLECULAR CLONING; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; SWINE;

ANIMALS; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; PRIMATES; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; SUIDAE;

EID: 34547844236     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11259-007-0006-7     Document Type: Article

References (23)

1. Bottino R., Balamurugan A.N., Giannoukakis N. and Trucco M., 2002a. Islet/pancreas transplantation: Challenges for pediatrics. Pediatric Diabetes, 3, 210-223
2. Bottino R., Balamurugan A.N., Bertera S., Pietropaolo M., Trucco M. and Piganelli J.D., 2002b. Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD-mimic compound. Diabetes, 51, 2561-2567
3. Cornelius J.G., Tchernev V., Kao K.J. and Peck A.B., 1997. In vitro -generation of islets in long-term cultures of pluripotent stem cells from adult mouse pancreas. Hormones and Metabolic Research, 29, 271-277
4. Dai Y., Vaught T.D., Boone J., Boone J., Chen S.H., Phelps C.J., Ball S., Monahan J.A., Jobst P.M., McCreath K.J., Lamborn A.E., Cowell-Lucero J.L., Wells K.D., Colman A., Palejaeva I.A. and Ayares D.L., 2002. Targeted disruption of the alpha1,3 galactosyl transferase gene in cloned pigs. Nature Biotechnology, 20, 251-255
5. Efrat S., 1998. Cell-based therapy for insulin-dependent diabetes mellitus. European Journal of Endocrinology, 138, 129-133
6. Galili V., 1993. Evolution and pathophysiology of the human natural anti-alpha galactosyltransferase IgG (anti-Gal) antibody. Springer Seminars in Immunopathology, 15, 155-171
7. Giannoukakis N. and Trucco M., 2003. Gene therapy technology applied to disorders of glucose metabolism: Promise, achievements and prospects. BioTechniques, 35, 122-145
8. Giannoukakis N., Rudert W.A., Robbins P.D. and Trucco M., 1999. Targeting autoimmune diabetes with gene therapy. Diabetes, 48, 2107-2121
9. Groth C.G., Korsgren O., Tibell A., Tollemar J., Moller E., Bolinder J., Ostman J., Reinholt F.P., Hellerstrom C. and Andersson A., 1994. Transplantation of porcine fetal pancreas to diabetic patients. The Lancet, 344, 1402-1404
10. Kenyon N.S., Chatzipetrou M., Masetti M., Ranuncoli A., Oliveira M., Wagner J.L., Kirk A.D., Harlan D.M., Burkly L.C. and Ricordi C., 1999. Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proceedings of the National Academy of Sciences of the United States of America, 96, 8132-8137
11. Koike C., Friday R.P., Nakashima I., Luppi P., Fung J.J., Rao A.S., Starzl T.E. and Trucco M., 2000. Isolation of the regulatory regions and genomic organization of the porcine alpha 1,3-galactosyltransferase gene. Transplantation, 70, 1275-1283
12. Koike C., Fung J.J., Geller D.A., Kannagi R., Libert T., Luppi P., Nakashima I., Profozich J., Rudert W., Sharma S.B., Starzl T.E. and Trucco M., 2002. Molecular basis of evolutionary loss of the alpha 1,3- galactosyltransferase gene in higher primates. The Journal of Biological Chemistry, 277, 10114-10120
13. Korsgren O., Sandler S., Landstrom A.S., Jansson L. and Andersson A., 1988. Large-scale production of fetal porcine pancreatic isletlike cell clusters. Transplantation, 45, 509-514
14. Lumelsky N., Blondel O., Laeng P., Velasco I., Ravin R. and McKay R., 2001. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science, 292, 1389-1394
15. Okamoto H. and Takasawa S., 2002. Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells. Diabetes, 51, S462-S473
16. Paraskevas S., Maysinger D., Wang R., Duguid T.P. and Rosenberg L., 2000. Cell loss in isolated human islets occurs by apoptosis. Pancreas, 20, 270-276
17. Phelps C.J., Koike C., Vaught T.D., Boone J., Wells K.D., Chen S.H., Ball S., Specht S.M., Polejaeva I.A., Monahan J.A., Jobst P.M., Sharma S.M., Lamborn A.E., Moore M., Demetris A.J., Rudert W., Bottino R., Bertera S., Trucco M., Starzl T.E., Dai Y. and Ayares D.L., 2003: Production of α1,3-galactosyltransferase deficient pigs by cloning. Science, 299, 411-414
18. Polejaeva I., Chen S.H., Vaught T., Page R., Mullins J., Ball S., Dai Y., Boone J., Walker S., Ayares D., Colman A. and Campbell K.H.S., 2000. Cloned pigs produced by nuclear transfer from adult somatic cells. Nature, 407, 86-90
19. Ricordi C., 2003. Islet transplantation: A brave new world. Diabetes, 52, 1595-1603
20. Rood P.P.M., Bottino R., Balamurugan A.N., Smetanka C.A., Ayares D., Murase N., Cooper D.K.C. and Trucco M., 2007. Reduction of early graft loss after intraportal porcine islet transplantation in monkeys. Transplantation, 83, 202-209
21. Shapiro A.M., Lakey J.R., Ryan E.A., Korbutt G.S., Toth E., Warnock G.L., Kneteman N.M. and Rajotte R., 2000. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. The New England Journal of Medicine, 343, 230-238
22. Shapiro A.M., Ricordi C., Hering B.J., Auchincloss H., Lindblad R., Robertson R.P., Secchi A., Brendel M.D., Berney T., Brennan D.C., Cagliero E., Alejandro R., Ryan E.A., DiMercurio B., Morel P., Polonsky K.S., Reems J., Bretzel R.G., Bertuzzi F., Froud T., Kandaswarmy R., Sutherland D.E.R., Eisenbarth G., Segal M., Preiksaitis J., Korbutt G.S., Barton F.B., Viviano L., Seyfert-Margolis V., Bluestone J. and Lakey J.R.T., 2006. Interntaional trial of the Edmonton protocol for islet transplantation. The New England Journal of Medicine, 355, 1318-1330
23. Tearle R.K., Tange M.J., Zannettino Z.L., Katerelos M., Shinkel T.A., Van Denderen B., Lonie A.J., Lyons I., Nottle M.B., Cox T., Becker C., Peura A.M., Wigley P.L., Crawford R.J., Robins A.J., Pearse M.J. and D'Apice A., 1996. The α1,3-galactosyltransferase knockout mouse. Transplantation, 61, 13-19