CR229, a novel derivative of β-carbolin-1-one, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation

Cancer Science

Volumn 98, Issue 9, 2007, Pages 1402-1407

  Kim, Min Kyoung ^a   Oh, Ha Lim ^a   Choi, Bu Young ^b   Lim, Haeyoung ^a   Cho, Youl Hee ^a   Lee, Chul Hoon ^a  

^a Hanyang University   (South Korea)

^b C and C Research Laboratories   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

6 BROMO 2,3,4,9 TETRAHYDROCARBOLIN 1 ONE; BETA CARBOLINE DERIVATIVE; CASPASE 3; CR 229; CYCLIN DEPENDENT KINASE; CYCLINE; CYTOCHROME C; PROTEIN P16; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL GROWTH; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN INDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARBOLINES; CASPASE 3; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; GROWTH INHIBITORS; HELA CELLS; HUMANS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34547799748     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2007.00552.x     Document Type: Article

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