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Volumn 3, Issue 3, 2007, Pages 1212-1222

Structural and energetic properties of organometallic ruthenium(II) diamine anticancer compounds and their interaction with nucleobases

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EID: 34547795624     PISSN: 15499618     EISSN: None     Source Type: Journal    
DOI: 10.1021/ct6003577     Document Type: Article
Times cited : (26)

References (44)
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    • This corresponds nearly to the most stable conformer found for the isolated p-cymene species in which the dihedral is 62.7° and the i-Pr hydrogen lies in the arene plane.
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    • This observation is not in agreement with the interpretation of a pKa, titration experiment carried out on a reaction mixture of, η6-biphenylRu(en)Cl, and 5′-CMP in which peaks were assigned to Ru-O(PO3)CMP and Ru-N3CMP but no one to Ru-O2CMP. Unfortunately, the same experiment with cytidine could not be performed due to the low concentration of the product (ref 42, An experiment with the pure nucleobase cytosine (as in our calculation) was not performed
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