Didanosine causes sensory neuropathy in an HIV/AIDS animal model: Impaired mitochondrial and neurotrophic factor gene expression

Brain

Volumn 130, Issue 8, 2007, Pages 2011-2023

  Zhu, Yu ^a   Antony, Joseph M ^b   Martinez, Jose A ^b   Glerum, D Moira ^a   Brussee, Valentine ^b   Hoke, Ahmet ^c   Zochodne, Douglas ^b   Power, Christopher ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BDNF; Didanosine; FIV; HIV; Mitochondria; Neuropathy

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOCHROME C OXIDASE; DIDANOSINE; NEUROTROPHIC FACTOR; NEUROTROPHIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIRETROVIRAL TOXIC NEUROPATHY; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FELINE IMMUNODEFICIENCY VIRUS; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VIVO STUDY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETROVIRUS INFECTION; SCHWANN CELL; SENSORY NEUROPATHY; SPINAL GANGLION; VIRUS REPLICATION;

ANIMALS; ANTI-HIV AGENTS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CATS; CELLS, CULTURED; DIDANOSINE; DISEASE MODELS, ANIMAL; FELINE ACQUIRED IMMUNODEFICIENCY SYNDROME; GANGLIA, SPINAL; MITOCHONDRIA; PERIPHERAL NERVOUS SYSTEM DISEASES; POLYMERASE CHAIN REACTION; VIRAL LOAD;

EID: 34547793113     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awm148     Document Type: Article

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