-
1
-
-
0021888013
-
The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation
-
Radford I.R. The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 48 1 (1985) 45-54
-
(1985)
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.
, vol.48
, Issue.1
, pp. 45-54
-
-
Radford, I.R.1
-
2
-
-
0026347249
-
Significance and measurement of DNA double-strand breaks in mammalian cells
-
Elia M.C., Deluca J.G., and Bradley M.O. Significance and measurement of DNA double-strand breaks in mammalian cells. Pharmacol. Ther. 51 3 (1991) 291-327
-
(1991)
Pharmacol. Ther.
, vol.51
, Issue.3
, pp. 291-327
-
-
Elia, M.C.1
Deluca, J.G.2
Bradley, M.O.3
-
3
-
-
0026303274
-
The role of DNA double-strand breaks in ionizing radiation-induced killing of eukaryotic cells
-
Iliakis G. The role of DNA double-strand breaks in ionizing radiation-induced killing of eukaryotic cells. Bioessays 13 12 (1991) 641-648
-
(1991)
Bioessays
, vol.13
, Issue.12
, pp. 641-648
-
-
Iliakis, G.1
-
4
-
-
26844545414
-
The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism
-
Pajonk F., Ophoven A.V., Weissenberger C., et al. The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism. BMC Cancer 5 1 (2005) 76
-
(2005)
BMC Cancer
, vol.5
, Issue.1
, pp. 76
-
-
Pajonk, F.1
Ophoven, A.V.2
Weissenberger, C.3
-
5
-
-
0036827964
-
A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation
-
Kim C.H., Park S.J., and Lee S.H. A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation. J. Pharmacol. Exp. Ther. 303 2 (2002) 753-759
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, Issue.2
, pp. 753-759
-
-
Kim, C.H.1
Park, S.J.2
Lee, S.H.3
-
6
-
-
0028038823
-
Cytotoxic and genetic effects of X-irradiation of human cells in the presence of chlorpromazine
-
Karmakar P., Dasgupta U.B., and Podder R.K. Cytotoxic and genetic effects of X-irradiation of human cells in the presence of chlorpromazine. Mutat. Res. 321 3 (1994) 159-164
-
(1994)
Mutat. Res.
, vol.321
, Issue.3
, pp. 159-164
-
-
Karmakar, P.1
Dasgupta, U.B.2
Podder, R.K.3
-
7
-
-
0020591753
-
Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine
-
Ganapathi R., and Grabowski D. Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine. Cancer Res. 43 8 (1983) 3696-3699
-
(1983)
Cancer Res.
, vol.43
, Issue.8
, pp. 3696-3699
-
-
Ganapathi, R.1
Grabowski, D.2
-
8
-
-
0023225318
-
Potentiation of sensitivity to bleomycin and the drug-induced DNA damage in EMT6 cells by calmodulin inhibitor trifluoperazine
-
Smith P.J., Mircheva J.J., and Bleechen N.M. Potentiation of sensitivity to bleomycin and the drug-induced DNA damage in EMT6 cells by calmodulin inhibitor trifluoperazine. Acta Physiol. Pharmacol. Bulg. 13 1 (1987) 41-45
-
(1987)
Acta Physiol. Pharmacol. Bulg.
, vol.13
, Issue.1
, pp. 41-45
-
-
Smith, P.J.1
Mircheva, J.J.2
Bleechen, N.M.3
-
9
-
-
0019123787
-
Damage of cellular functions by trifluoperazine, a calmodulin-specific drug
-
Osborn M., and Weber K. Damage of cellular functions by trifluoperazine, a calmodulin-specific drug. Exp. Cell. Res. 130 2 (1980) 484-488
-
(1980)
Exp. Cell. Res.
, vol.130
, Issue.2
, pp. 484-488
-
-
Osborn, M.1
Weber, K.2
-
10
-
-
0033621288
-
Inhibition of trifluoperazine-induced DNA fragmentation by cyclic AMP mediated signaling
-
Kang U.G., Kim M.J., Suh P.G., et al. Inhibition of trifluoperazine-induced DNA fragmentation by cyclic AMP mediated signaling. Mol. Cell. 9 6 (1999) 596-602
-
(1999)
Mol. Cell.
, vol.9
, Issue.6
, pp. 596-602
-
-
Kang, U.G.1
Kim, M.J.2
Suh, P.G.3
-
11
-
-
0343374101
-
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation
-
Hidaka H., Sasaki Y., Tanaka T., et al. N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 78 7 (1981) 4354-4357
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, Issue.7
, pp. 4354-4357
-
-
Hidaka, H.1
Sasaki, Y.2
Tanaka, T.3
-
12
-
-
0022343334
-
Characteristics of the cytotoxic effects of the phenothiazine class of calmodulin antagonists
-
Hait W.N., and Lee G.L. Characteristics of the cytotoxic effects of the phenothiazine class of calmodulin antagonists. Biochem. Pharmacol. 34 22 (1985) 3973-3978
-
(1985)
Biochem. Pharmacol.
, vol.34
, Issue.22
, pp. 3973-3978
-
-
Hait, W.N.1
Lee, G.L.2
-
13
-
-
0035976384
-
Induction of apoptosis by phenothiazine derivatives in V79 cells
-
Karmakar P., Natarajan A.T., Podder R.K., et al. Induction of apoptosis by phenothiazine derivatives in V79 cells. Toxicol. Lett. 125 1-3 (2001) 19-28
-
(2001)
Toxicol. Lett.
, vol.125
, Issue.1-3
, pp. 19-28
-
-
Karmakar, P.1
Natarajan, A.T.2
Podder, R.K.3
-
14
-
-
0035878747
-
Inhibition of DNA replication by tirapazamine
-
Peters K.B., Wang H., Brown J.M., et al. Inhibition of DNA replication by tirapazamine. Cancer Res. 61 14 (2001) 5425-5431
-
(2001)
Cancer Res.
, vol.61
, Issue.14
, pp. 5425-5431
-
-
Peters, K.B.1
Wang, H.2
Brown, J.M.3
-
15
-
-
0036007541
-
Augmentation of apoptosis by the combination of bleomycin with trifluoperazine in the presence of mutant p53
-
Sullivan G.F., Garcia-Welch A., White E., et al. Augmentation of apoptosis by the combination of bleomycin with trifluoperazine in the presence of mutant p53. J. Exp. Ther. Oncol. 2 1 (2002) 19-26
-
(2002)
J. Exp. Ther. Oncol.
, vol.2
, Issue.1
, pp. 19-26
-
-
Sullivan, G.F.1
Garcia-Welch, A.2
White, E.3
-
16
-
-
0023904582
-
Antitumor and toxic effects of combination chemotherapy with bleomycin and a phenothiazine anticalmodulin agent
-
Hait W.N., Lazo J.S., Chen D.L., et al. Antitumor and toxic effects of combination chemotherapy with bleomycin and a phenothiazine anticalmodulin agent. J. Natl. Cancer. Inst. 80 4 (1988) 246-250
-
(1988)
J. Natl. Cancer. Inst.
, vol.80
, Issue.4
, pp. 246-250
-
-
Hait, W.N.1
Lazo, J.S.2
Chen, D.L.3
-
17
-
-
0024592461
-
Phase I trial of combined therapy with bleomycin and the calmodulin antagonist, trifluoperazine
-
Hait W.N., Morris S., Lazo J.S., et al. Phase I trial of combined therapy with bleomycin and the calmodulin antagonist, trifluoperazine. Cancer Chemother. Pharmacol. 23 6 (1989) 358-362
-
(1989)
Cancer Chemother. Pharmacol.
, vol.23
, Issue.6
, pp. 358-362
-
-
Hait, W.N.1
Morris, S.2
Lazo, J.S.3
-
18
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end joining
-
Lieber M.R., Ma Y., Pannicke U., et al. Mechanism and regulation of human non-homologous DNA end joining. Nat. Rev. Mol. Cell. Biol. 4 9 (2003) 712-720
-
(2003)
Nat. Rev. Mol. Cell. Biol.
, vol.4
, Issue.9
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
-
19
-
-
0030814125
-
Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay
-
Rosenzweig K.E., Youmell M.B., Palayoor S.T., et al. Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay. Clin. Cancer Res. 3 7 (1997) 1149-1156
-
(1997)
Clin. Cancer Res.
, vol.3
, Issue.7
, pp. 1149-1156
-
-
Rosenzweig, K.E.1
Youmell, M.B.2
Palayoor, S.T.3
-
20
-
-
0032916940
-
Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks
-
Chernikova S.B., Wells R.L., and Elkind M.M. Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. Radiat. Res. 151 2 (1999) 159-166
-
(1999)
Radiat. Res.
, vol.151
, Issue.2
, pp. 159-166
-
-
Chernikova, S.B.1
Wells, R.L.2
Elkind, M.M.3
-
21
-
-
0027304013
-
V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder
-
Hsieh C.L., Arlett C.F., and Lieber M.R. V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder. J. Biol. Chem. 268 27 (1993) 20105-20109
-
(1993)
J. Biol. Chem.
, vol.268
, Issue.27
, pp. 20105-20109
-
-
Hsieh, C.L.1
Arlett, C.F.2
Lieber, M.R.3
-
22
-
-
0034548910
-
Cisplatin-DNA adducts inhibit translocation of the KU subunits of DNA-PK
-
Turuchi J.J., Karen M.H., and Zhou Y. Cisplatin-DNA adducts inhibit translocation of the KU subunits of DNA-PK. Nucleic Acids Res. 28 23 (2000) 4634-4641
-
(2000)
Nucleic Acids Res.
, vol.28
, Issue.23
, pp. 4634-4641
-
-
Turuchi, J.J.1
Karen, M.H.2
Zhou, Y.3
-
23
-
-
0034810574
-
DNA-dependent protein kinase is inhibited by trifluoperazine
-
Eriksson A., Yachnin J., Lewensohn R., et al. DNA-dependent protein kinase is inhibited by trifluoperazine. Biochem. Biophys. Res. Commun. 283 4 (2001) 726-731
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, Issue.4
, pp. 726-731
-
-
Eriksson, A.1
Yachnin, J.2
Lewensohn, R.3
-
24
-
-
0021987630
-
Measurement of micronuclei in lymphocytes
-
Fenech M., and Morley A.A. Measurement of micronuclei in lymphocytes. Mutat. Res. 147 1/2 (1985) 29-36
-
(1985)
Mutat. Res.
, vol.147
, Issue.1-2
, pp. 29-36
-
-
Fenech, M.1
Morley, A.A.2
-
25
-
-
34248213011
-
Direct effects of caffeine on osteoblastic cells metabolism: the possible casual effect of caffeine on the formation of osteoporesis
-
Tsuang Y.-H., Sun J.-S., Chen L.-T., et al. Direct effects of caffeine on osteoblastic cells metabolism: the possible casual effect of caffeine on the formation of osteoporesis. J. Orthop. Surg. Res. 1 7 (2006) 186-194
-
(2006)
J. Orthop. Surg. Res.
, vol.1
, Issue.7
, pp. 186-194
-
-
Tsuang, Y.-H.1
Sun, J.-S.2
Chen, L.-T.3
-
26
-
-
0024421553
-
CHEF electrophoresis, a sensitive technique for the determination of DNA double-strand breaks
-
Blocher D., Einspenner M., and Zajackowski J. CHEF electrophoresis, a sensitive technique for the determination of DNA double-strand breaks. Int. J. Radiat. Biol. 56 4 (1989) 437-448
-
(1989)
Int. J. Radiat. Biol.
, vol.56
, Issue.4
, pp. 437-448
-
-
Blocher, D.1
Einspenner, M.2
Zajackowski, J.3
-
27
-
-
0025335271
-
Measurement of radiation-induced DNA double-strand breaks by pulsed-field gel electrophoresis
-
Ager D.D., Dewey W.C., Gardiner K., et al. Measurement of radiation-induced DNA double-strand breaks by pulsed-field gel electrophoresis. Radiat. Res. 122 2 (1990) 181-187
-
(1990)
Radiat. Res.
, vol.122
, Issue.2
, pp. 181-187
-
-
Ager, D.D.1
Dewey, W.C.2
Gardiner, K.3
-
28
-
-
0026709051
-
A fourth complementation group among ionizing radiation-sensitive Chinese hamster cell mutants defective in DNA double-strand break repair
-
Zdzienicka M.Z., Van W.N., and Van D.S.G.P. A fourth complementation group among ionizing radiation-sensitive Chinese hamster cell mutants defective in DNA double-strand break repair. Radiat. Res. 131 3 (1992) 309-314
-
(1992)
Radiat. Res.
, vol.131
, Issue.3
, pp. 309-314
-
-
Zdzienicka, M.Z.1
Van, W.N.2
Van, D.S.G.P.3
-
29
-
-
0027299912
-
Field-inversion gel electrophoresis analysis of the induction and rejoining of DNA double-strand breaks in cells embedded in agarose
-
Kysela B.P., Michael B.D., and Arrand J.E. Field-inversion gel electrophoresis analysis of the induction and rejoining of DNA double-strand breaks in cells embedded in agarose. Radiat. Res. 134 1 (1993) 107-111
-
(1993)
Radiat. Res.
, vol.134
, Issue.1
, pp. 107-111
-
-
Kysela, B.P.1
Michael, B.D.2
Arrand, J.E.3
-
30
-
-
0029803485
-
Wortmannin is a potent inhibitor DNA double strand break but not single strand break repair in Chinese hamster ovary cells
-
Boulton S., Kyle S., Yalcintepe L., and Durkacz B.W. Wortmannin is a potent inhibitor DNA double strand break but not single strand break repair in Chinese hamster ovary cells. Carcinogenesis 17 11 (1996) 2285-2290
-
(1996)
Carcinogenesis
, vol.17
, Issue.11
, pp. 2285-2290
-
-
Boulton, S.1
Kyle, S.2
Yalcintepe, L.3
Durkacz, B.W.4
-
31
-
-
2342459790
-
DNA damage-induced apoptosis
-
Chris J.N., and Boris Z. DNA damage-induced apoptosis. Oncogene 23 16 (2004) 2797-2808
-
(2004)
Oncogene
, vol.23
, Issue.16
, pp. 2797-2808
-
-
Chris, J.N.1
Boris, Z.2
-
32
-
-
0029313915
-
Mammalian DNA damage-inducible genes associated with growth arrest and apoptosis
-
Smith M.L., and Fornace Jr. A.J. Mammalian DNA damage-inducible genes associated with growth arrest and apoptosis. Mutat. Res. 340 2/3 (1996) 109-124
-
(1996)
Mutat. Res.
, vol.340
, Issue.2-3
, pp. 109-124
-
-
Smith, M.L.1
Fornace Jr., A.J.2
-
33
-
-
0035796042
-
Homologous recombinational repair of DNA ensures mammalian chromosome stability
-
Thompson L.H., and Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat. Res. 477 1/2 (2001) 131-153
-
(2001)
Mutat. Res.
, vol.477
, Issue.1-2
, pp. 131-153
-
-
Thompson, L.H.1
Schild, D.2
-
34
-
-
0034031137
-
DNA double strand break repair in mammalian cells
-
Karran P. DNA double strand break repair in mammalian cells. Curr. Opin. Genet. Dev. 10 2 (2000) 144-150
-
(2000)
Curr. Opin. Genet. Dev.
, vol.10
, Issue.2
, pp. 144-150
-
-
Karran, P.1
-
35
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
Van G.D.C., Hoeijmakers J.H., and Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet. 2 3 (2001) 196-206
-
(2001)
Nat. Rev. Genet.
, vol.2
, Issue.3
, pp. 196-206
-
-
Van, G.D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
37
-
-
0022001235
-
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists
-
Lazo J.S., Hait W.N., Kennedy K.A., et al. Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists. Mol. Pharmacol. 27 3 (1985) 387-393
-
(1985)
Mol. Pharmacol.
, vol.27
, Issue.3
, pp. 387-393
-
-
Lazo, J.S.1
Hait, W.N.2
Kennedy, K.A.3
-
38
-
-
0026662014
-
Potentiation of cisplatin cytotoxicity in human ovarian carcinoma cell lines by trifluoperazine, a calmodulin inhibitor
-
Perez R.P., Handel L.M., and Hamilton T.C. Potentiation of cisplatin cytotoxicity in human ovarian carcinoma cell lines by trifluoperazine, a calmodulin inhibitor. Gynecol. Oncol. 46 1 (1992) 82-87
-
(1992)
Gynecol. Oncol.
, vol.46
, Issue.1
, pp. 82-87
-
-
Perez, R.P.1
Handel, L.M.2
Hamilton, T.C.3
-
39
-
-
0021911133
-
Inhibition of DNA repair by trifluoperazine
-
Charp P.A., and Regan J.D. Inhibition of DNA repair by trifluoperazine. Biochim. Biophys. Acta 824 1 (1985) 34-39
-
(1985)
Biochim. Biophys. Acta
, vol.824
, Issue.1
, pp. 34-39
-
-
Charp, P.A.1
Regan, J.D.2
-
40
-
-
0035201216
-
In vivo association of Ku with mammalian origins of DNA replication
-
Novac O., Matheos D., Araujo F.D., et al. In vivo association of Ku with mammalian origins of DNA replication. Mol. Biol. Cell. 12 11 (2001) 3386-3401
-
(2001)
Mol. Biol. Cell.
, vol.12
, Issue.11
, pp. 3386-3401
-
-
Novac, O.1
Matheos, D.2
Araujo, F.D.3
-
41
-
-
3042838562
-
Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine
-
Block W.D., Merkle D., Meek K., et al. Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine. Nucleic Acids Res. 32 6 (2004) 1967-1972
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.6
, pp. 1967-1972
-
-
Block, W.D.1
Merkle, D.2
Meek, K.3
-
42
-
-
0034733925
-
Calmodulin antagonists and cAMP inhibit ionizing-radiation-enhancement of double-strand-break repair in human cells
-
Wang Y., Mallya S.M., and Sikpi M.O. Calmodulin antagonists and cAMP inhibit ionizing-radiation-enhancement of double-strand-break repair in human cells. Mutat. Res. 460 1 (2000) 29-39
-
(2000)
Mutat. Res.
, vol.460
, Issue.1
, pp. 29-39
-
-
Wang, Y.1
Mallya, S.M.2
Sikpi, M.O.3
-
43
-
-
3042791448
-
Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity
-
Bugreev D.V., and Mazin A.V. Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity. Proc. Natl. Acad. Sci. U.S.A. 101 27 (2004) 9988-9993
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, Issue.27
, pp. 9988-9993
-
-
Bugreev, D.V.1
Mazin, A.V.2
-
44
-
-
0033020393
-
A combined biochemical and cytogenetic study of thioridazine-induced damage to nucleic acids
-
Pantazaki A.A., and Lialiaris T.S. A combined biochemical and cytogenetic study of thioridazine-induced damage to nucleic acids. Mutagenesis 14 2 (1999) 243-248
-
(1999)
Mutagenesis
, vol.14
, Issue.2
, pp. 243-248
-
-
Pantazaki, A.A.1
Lialiaris, T.S.2
-
45
-
-
33645468792
-
Multiple, disparate roles for calcium signaling in apoptosis of human prostate and cervical cancer cells exposed to diindolylmethane
-
Savino III J.A., Evans J.F., Rabinowitz D., et al. Multiple, disparate roles for calcium signaling in apoptosis of human prostate and cervical cancer cells exposed to diindolylmethane. Mol. Cancer Ther. 5 3 (2006) 556-563
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.3
, pp. 556-563
-
-
Savino III, J.A.1
Evans, J.F.2
Rabinowitz, D.3
|