Evaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifolia

Journal of Ethnopharmacology

Volumn 94, Issue 1, 2004, Pages 93-100

  Jorge, R M ^a   Leite, J P V ^b   Oliveira, A B ^b   Tagliati, C A ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b MG   (Brazil)

Author keywords

Anti inflammatory; Antinociceptive; Gastric ulcer; Maytenus ilicifolia

Indexed keywords

ACETIC ACID ETHYL ESTER; CARRAGEENAN; CIMETIDINE; FORMALDEHYDE; HEXANE; INDOMETACIN; MAYTENUS ILICIFOLIA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; FEMALE; MALE; NOCICEPTION; NONHUMAN; PAW EDEMA; RAT; STOMACH PH; STOMACH ULCER; ULCER HEALING;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-ULCER AGENTS; CIMETIDINE; FEMALE; INDOMETHACIN; MALE; MAYTENUS; MICE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; STOMACH; STOMACH ULCER;

EID: 3242734920     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2004.04.019     Document Type: Article

References (50)

1. Abou-Mohamed G., El-Kashef H.A., Salem H.A., Elmazar M.M. Effect of zinc on the anti-inflammatory and ulcerogenic activities of indometacin and diclofenac. Pharmacology. 50:1995;266-272
2. Aguwa C.N. Gastrointestinal effects of the extracts of Rhigiocarya racemifera (Menispermaceae). General Pharmacology. 16:1985;387-390
3. Aguwa C.N., Lawal A.M. Pharmacological studies on the active principles of Calliandra portoricensis leaf extracts. Journal of Ethnopharmacology. 22:1988;63-71
4. Alarcón de la Lastra C., Martin M.J., La Casa M.C., López A., Motilva V. Effects of cisapride on ulcer formation and gastric secretion in rats: comparison with ranitidine and omeprazol. General Pharmacology. 27:1996;1415-1420
5. Antônio M.A., Souza-Brito A.R.M. Oral anti-inflammatory and antiulcerogenic activities of a hydroalcoholic extract and partitioned fractions of Turnera ulmifolia (Turneraceae). Journal of Ethnopharmacology. 61:1998;215-228
6. Balbach, A., 1980. A Flora Nacional na Medicina Doméstica, 11th ed. A edificação do lar, São Paulo, p. 885.
7. Born, G.C.C., 2000. Plantas medicinais da Mata Atlântica (Vale do Ribeira-SP), Tese de doutorado, Universidade de São Paulo, São Paulo, p. 289.
8. Bossolani, M.P., 2000. Mecanismo molecular da ação anti-secretora ácida gástrica de extratos e frações isoladas de Maytenus ilicifolia Mart e Maytenus aquifolium Mart, Tese de mestrado, Universidade Federal de São Paulo, São Paulo, p. 108.
9. Bravo L., Escolar G., Navarro C., Fontarnau R., Bulbena O. Effect of zinc acexamate on gastric lesions induced by aspirin: a morphological study. European Journal of Pharmacology. 190:1990;59-65
10. Bulbena O., Escolar G., Navarro C., Bravo L., Pfeiffer C.J. Gastroprotective effect of zinc acexamate against damage induced by nonsteroidal antiinflammatory drugs. A morphological study. Digestive Disease and Science. 38:1993;730-739
11. Cho C.H., Ogle C.W., Dai S. Effects of zinc chloride on gastric secretion and ulcer formation in pylorus-occluded rats. European Journal of Pharmacology. 38:1976;337-341
12. Cho C.H., Koo H.W.L., Garg G.P., Ogle C.W. Stress-induced gastric ulceration: its aetiology and clinical implications. Scandinavian Journal of Gastroenterology. 27:1992;257-262
13. Corrêa, M.P., 1984. Dicionário das plantas úteis do Brasil e das exóticas cultivadas. Ministério da Agricultura, Ed. Instituto Brasileiro de Desenvolvimento Florestal, Rio de Janeiro, 6, pp. 134-135.
14. Costa V.B., Coube C.S., Marinho B.G., Matheus M.E., Leitão S.G., Fernandes P.D. Antiinflammatory and analgesic activity of Bouchea fluminensis. Fitoterapia. 74:2003;364-371
15. Cruz, G.L., 1982. Dicionário das Plantas Úteis do Brasil, second ed. Civilização Brasileira, São Paulo, pp. 335-336.
16. Escolar G., Navarro C., Sendrós S., Bulbena O. Effect of cold-restraint stress and zinc acexamate on gastric mucus production in intact glands. Archives International Pharmacodynamic. 290:1987;128-137
17. Esplugues J.V., Bulbena O., Escolar G., Martí-Bonmatí E., Esplugues J. Effects of zinc acexamate on gastric mucosal resistance factors. European Journal of Pharmacology. 109:1985;145-151
18. Ezaki N., Kato M., Takizawa N., Morinoto S., Nonaka G., Nishioka I. Pharmacological studies on Linderae umbellatae Ramus, IV. Effects of condensed tannin related compound on peptic activity and stress-induced gastric lesions in mice. Planta Medica. 1:1985;34-38
19. Farnsworth, N.R., Soejarto, D.D., 1991. Global importance of medicinal plants. In: Akerele, O., Heywood, V., Synge, H. (Eds.), Conservation of Medicinal Plants. Cambridge University Press, Cambridge, pp. 25-51.
20. Freire S.M., Torres L.M., Roque N.F., Soucar C., Lapa A.J. Analgesic activity of a triterpene isolated from Scoparia dulcis L. (Vassourinha). Memorial do Instituto Oswaldo Cruz. 86:1991;149-151
21. Galati E.M., Monforte M.T., Kirjavainen S., Forestieri A.M., Trovato A., Tripodo M.M. Biological effects of hesperidin, a citrus flavonoid (Note I): anti-iflammatory and analgesic activity. Farmaco. 40:1994;709-712
22. Gonzalez J.G., Monache G.D., Monache F.D., Marini-Bettolò G.B. Chuchuasca - a drug used in folk medicine in the Amazonian and Andean areas. A chemical study of Maytenus leavis. Journal of Ethnopharmacology. 5:1982;73-77
23. Gonzalez F.G., Di Stasi L.C. Antiulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice. Phytomedicine. 9:2002;125-134
24. Itokawa H., Shirota O., Ikuta H., Morita H., Takeya K., Itaka Y. Triterpenes from Maytenus ilicifolia. Phytochemistry. 30:1991;3713-3716
25. Khennouf S., Benabdallah H., Gharzouli K., Amira S., Ito H., Kim T.H., Yoshida T., Gharzouli A. Effect of tannins from Quercus suber and Quercus coccifera leaves on ethanol-induced gastric lesions in mice. Journal of Agricultural & Food Chemistry. 51:2003;1469-1473
26. Leite J.P.V., Rastrelli L., Romussi G., Oliveira A.B., Vilegas J.H.Y., Vilegas W., Pizza C. Isolation and HPLC quantitative analysis of Flavonoid glycosids from Brasilian beverages (Maytenus ilicifolia and Maytenus aquifolium). Journal of Agricultural & Food Chemistry. 49:2001;3796-3801
27. Lewis D.A., Hanson P.J. Anti-ulcer drugs of plant origin. Progress Medicinal Chemistry. 28:1991;201-231
28. Martin M.J., Marhuenda E., Alarcón de la Lastra C. Esculine, ranitidine and carbenoxolone: different modes of action on gastric mucosa. General Pharmacology. 22:1991;1001-1004
29. Matos, F.J.A., 1988. Introdução à Fitoquímica Experimental, first ed. Editora da Universidade Federal do Ceará, Fortaleza, p. 126.
30. Miller T.A. Mechanism of stress-related mucosal damage. American Journal of Medicine. 83:1987;8-14
31. Nascimento J.W.L., Santos L.H., Nothenberg M.S., Coelho M.M., Oga S., Tagliati C.A. Anti-inflammmatory activity and gastric lesions induced by zinc-tenoxicam. Pharmacology. 68:2003;64-69
32. Niero R., Moser R., Busato A.C.B., Yunes R.A., Reis A. A comparative chemical study of Maytenus ilicifolia Mart. Reiss and Maytenus robusta. Reiss (Celastraceae). Zeitschrift fur Naturforschung. 56:2001;158-161
33. Nikiema J.B., Vanhaelen-Fastre R., Vanhaelen M., Fontaine J., De Graef C., Heenen M. Effects of antiinflammatory triterpenes isolated from Leptadenia hastata latex on keratinocyte proliferation. Phytoteraphy Research. 15:2001;131-134
34. Oliveira G.M.O., Monteiro M.G., Macaúbas C., Barbosa V.P., Carlini E.A. Pharmacological and toxicologic effects of two Maytenus species in laboratory animals. Journal of Ethnopharmacology. 34:1991;29-41
35. Pelzer L.E., Guardia T., Osvaldo Juarez A., Guerreiro E. Acute and chronic antiinflammatory effects of plant flavonoids. Farmaco. 53:1998;421-424
36. Pfeiffer C.J., Bulbena O., Esplugues J.V., Escolar G., Navarro C., Esplugues J. Anti-ulcer and membrane stabilizing actions of zinc acexamate. Archives International Pharmacodynamic. 285:1987;148-157
37. Queiroga C.L., Silva G.F., Dias P.C., Possenti A., Carvalho J.E. Evaluation of the antiulcerogenic activity of friedelan-3β-ol and friedelin isolated from Maytenus ilicifolia (Celastraceae). Journal of Ethnopharmacology. 72:2000;465-468
38. Rainsford, K.D., 1989. Mechanisms of gastrointestinal damage by non-steroidal anti-inflammatory drugs. In: Szabo, S., Pfeiffer, C.J. (Eds.), Ulcer Disease: New Aspects of Pathogenesis and Pharmacology. Boca Raton, CRC Press, FL, pp. 3-13.
39. Robak J., Gryglewski R.J. Bioactivity of flavonoids. Polish Journal of Pharmacology. 48:1996;555-564
40. Robert A., Nezamis J.E., Lancastar C., Hanchar A.J. Cytoprotection by prostaglandin in rats: Prevention of gastric necrosis produced by alcohol, hydrochloric acid, sodium hydroxide, hypertonic sodium chloride and thermal injury. Gastroenterology. 77:1979;433-443
41. Robert A., Leung F.W., Kaiser D.G., Guth P.H. Potentiation of aspirin-induced gastric lesions by exposure to cold in rats. Role of acid secretion, mucosal blood flow, and gastric mucosal prostanoid content. Gastroenterology. 97:1989;1147-1158
42. Safavhi H., Sailer E.R. Antiinflammatory actions of pentacyclic triterpenes. Planta Medica. 63:1997;487-493
43. Sairam K., Rao Ch.V., Dora Babu M., Vijay Kumar K., Agrawal V.K., Goel R.K. Antiulcerogenic effect of methanolic extract of Emblica officinallis: an experimental study. Journal of Pharmacology. 82:2002;1-9
44. Shirota O., Morita H., Takeya K., Itokawa H. Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus ilicifolia. Journal of Natural Products. 57:1994;1675-1681
45. Souza-Formigoni M.L.O., Oliveira M.G.M., Monteiro M.G., Silveira-Filho N.G., Braz S., Carlini E.A. Antiulcerogenic effects of two Maytenus species in laboratory animals. Journal of Ethnopharmacology. 34:1991;21-27
46. Szelenyi I., Thiemer K. Distention ulcer as a model for testing of drugs for ulcerogenic side effects. Archives of Toxicology. 41:1978;99-105
47. Tabach R., Oliveira W.P. Evaluation of the antiulcerogenic activity of a dry extract of Maytenus ilicifolia Martius ex. Reiss produced by a jet spouted bed dryer. Pharmazie. 58:2003;573-576
48. Vaz Z.R., Cechinel Filho V., Yunes R.A., Calixto J.B. Antinociceptive action of 2-(4-bromobenzoyl)-3-methyl-4,6-dimethoxy benzofuran, a novel xanthine derivative on chemical and thermal models of nociception in mice. Journal of Pharmacology and Experimental Therapeutics. 278:1996;304-312
49. Vilegas J.H.I., Lanças F.M., Cervi A.C. High-resolution gas-chromatography analysis of 'espinheira-santa' (Maytenus ilicifolia and Maytenus aquifolium): analysis of crude drug adulterations. Phytotherapy Research. 8:1994;241-244
50. Vilegas W., Sanommiya M., Rastrelli L., Pizza C. Isolation and structure elucidation of two new flavonoid glycosides from the infusion of Maytenus aquifolium leaves. Evaluation of the antiulcer activity of the infusion. Journal of Agricultural & Food Chemistry. 47:1999;403-406