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Volumn 13, Issue 15, 2007, Pages

HKI-272 in non-small cell lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

BIBW 2992; CL 387785; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; FOCAL ADHESION KINASE; GEFITINIB; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HKI 272; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PF 299804; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; PHOSPHOLIPASE D; PROTEIN KINASE B; PROTEIN SHC; PROTEIN TYROSINE KINASE; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 34547749490     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-0369     Document Type: Article
Times cited : (52)

References (24)
  • 1
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer : Amphiregulin and microvessel count are independent prognostic indicators of survival
    • Fontanini G, De Laurentiis M, Vignati S, et al. Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer : amphiregulin and microvessel count are independent prognostic indicators of survival. Clin Cancer Res 1998;4:241-9.
    • (1998) Clin Cancer Res , vol.4 , pp. 241-249
    • Fontanini, G.1    De Laurentiis, M.2    Vignati, S.3
  • 2
    • 0027159063 scopus 로고
    • Differential expressionof the epidermal growth factor receptorand its ligands in primary non-small cell lung cancers and adjacent benign lung
    • Rusch V, Baselga J, Cordon-Cardo C, et al. Differential expressionof the epidermal growth factor receptorand its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993;53:2379-85.
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3
  • 3
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005;5:341-54.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 4
    • 0037429652 scopus 로고    scopus 로고
    • ErbB-targeted therapeutic approaches in human cancer
    • Arteaga CL. ErbB-targeted therapeutic approaches in human cancer. Exp Cell Res 2003;284:122-30.
    • (2003) Exp Cell Res , vol.284 , pp. 122-130
    • Arteaga, C.L.1
  • 5
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000;19:6550-65.
    • (2000) Oncogene , vol.19 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 6
    • 0012381722 scopus 로고    scopus 로고
    • Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
    • Fukuoka M, Yano S, Giaccone G, et al. Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003;21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 7
    • 2642539590 scopus 로고    scopus 로고
    • Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, "Iressa") on an expanded access study
    • Janne PA, Gurubhagavatula S, Yeap BY, et al. Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, "Iressa") on an expanded access study. Lung Cancer 2004;44:221-30.
    • (2004) Lung Cancer , vol.44 , pp. 221-230
    • Janne, P.A.1    Gurubhagavatula, S.2    Yeap, B.Y.3
  • 8
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003;290:2149-58.
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 9
    • 1842509828 scopus 로고    scopus 로고
    • Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
    • Miller VA , Kris MG, Shah N, et al. Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 2004;22:1103-9.
    • (2004) J Clin Oncol , vol.22 , pp. 1103-1109
    • Miller, V.A.1    Kris, M.G.2    Shah, N.3
  • 10
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer - molecular and clinical predictors of outcome
    • Tsao MS, Sakurada A, Cutz JC, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005;353:133-44.
    • (2005) N Engl J Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 11
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 12
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:497-500.
    • (2004) Science , vol.304 , pp. 497-500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 13
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004;101:13306-11.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 14
    • 33749677330 scopus 로고    scopus 로고
    • EGFR targeted therapy: View from biological standpoint
    • Ji H, Sharpless NE, Wong KK. EGFR targeted therapy: view from biological standpoint. Cell Cycle 2006;5:2072-6.
    • (2006) Cell Cycle , vol.5 , pp. 2072-2076
    • Ji, H.1    Sharpless, N.E.2    Wong, K.K.3
  • 15
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005;97:339-46.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 16
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group Study
    • Hirsch FR, Varella-Garcia M, McCoy J, et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study. J Clin Oncol 2005;23:6838-45.
    • (2005) J Clin Oncol , vol.23 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 17
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, Boggon TJ, Dayaram T, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005;352:786-92.
    • (2005) N Engl J Med , vol.352 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3
  • 18
    • 21144439000 scopus 로고    scopus 로고
    • Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
    • Kwak EL, Sordella R, Bell DW, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005;102:7665-70.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7665-7670
    • Kwak, E.L.1    Sordella, R.2    Bell, D.W.3
  • 19
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005;2:e73.
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3
  • 20
    • 2542582261 scopus 로고    scopus 로고
    • Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase
    • Rabindran SK, Discafani CM, Rosfjord EC, et al. Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase. Cancer Res 2004;64:3958-65.
    • (2004) Cancer Res , vol.64 , pp. 3958-3965
    • Rabindran, S.K.1    Discafani, C.M.2    Rosfjord, E.C.3
  • 21
    • 33744788136 scopus 로고    scopus 로고
    • The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
    • Ji H, Li D, Chen L, et al. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell 2006;9:485-95.
    • (2006) Cancer Cell , vol.9 , pp. 485-495
    • Ji, H.1    Li, D.2    Chen, L.3
  • 22
    • 33646716077 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors
    • Ji H, Zhao X, Yuza Y, et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci U S A 2006;103:7817- 22.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7817-7822
    • Ji, H.1    Zhao, X.2    Yuza, Y.3
  • 23
    • 33746154236 scopus 로고    scopus 로고
    • Non-small-celllung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272
    • Shimamura T, Ji H, Minami Y, etal. Non-small-celllung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272. Cancer Res 2006;66:6487-91.
    • (2006) Cancer Res , vol.66 , pp. 6487-6491
    • Shimamura, T.1    Ji, H.2    Minami, Y.3
  • 24
    • 33751416678 scopus 로고    scopus 로고
    • HKI-272, an irreversible pan erbB receptor tyrosine kinase inhibitor: Preliminary phase 1 results in patients with solid tumors
    • Wong KK, Fracasso PM, Bukowski RM, et al. HKI-272, an irreversible pan erbB receptor tyrosine kinase inhibitor: Preliminary phase 1 results in patients with solid tumors. J Clin Oncol 2006;24:3018.
    • (2006) J Clin Oncol , vol.24 , pp. 3018
    • Wong, K.K.1    Fracasso, P.M.2    Bukowski, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.