Protagonistic pleiotropy: Why cancer may be the only pathogenic effect of accumulating nuclear mutations and epimutations in aging

Mechanisms of Ageing and Development

Volumn 128, Issue 7-8, 2007, Pages 456-459

  de Grey, Aubrey D N J ^a  

^a Methuselah Foundation   (United States)

Author keywords

Aging; Cancer; Epimutations; Nuclear mutations

Indexed keywords

HISTONE;

AGING; ARTICLE; CANCER MORTALITY; CARCINOGENESIS; CHROMOSOME DAMAGE; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; EPIGENETICS; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; METHYLATION; NONHUMAN; PATHOGENESIS; PLEIOTROPY; POINT MUTATION; PRIORITY JOURNAL; REDUNDANCY ANALYSIS;

AGING; ANIMALS; EPIGENESIS, GENETIC; GENOMIC INSTABILITY; HUMANS; MUTATION; NEOPLASMS;

ANIMALIA; MAMMALIA;

EID: 34547689359     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2007.05.005     Document Type: Article

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