Effective modulation of DNA duplex stability by reversible transition metal complex formation in the minor groove

Journal of the American Chemical Society

Volumn 129, Issue 30, 2007, Pages 9392-9400

  Kalek, Marcin ^a,b   Madsen, Andreas S ^a   Wengel, Jesper ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DUPLEX STABILIZATION; STABILITY MODULATION;

ADDITION REACTIONS; COMPLEXATION; MOLECULAR MODELING; MONOMERS; THERMODYNAMIC STABILITY;

DNA;

2' AMINO 2' DEOXYURIDINE; 2' AMINO LOCKED NUCLEIC ACID; DOUBLE STRANDED DNA; EDETIC ACID; LIGAND; LOCKED NUCLEIC ACID; METAL COMPLEX; MONOMER; NICKEL; NITROGEN; PYRIDINE DERIVATIVE; TRANSITION ELEMENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; DNA HYBRIDIZATION; MOLECULAR MODEL; REACTION ANALYSIS; STRUCTURE ANALYSIS; THERMOSTABILITY;

CATIONS; CIRCULAR DICHROISM; DEOXYURIDINE; DNA; EDETIC ACID; LIGANDS; MODELS, MOLECULAR; NICKEL; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; ORGANOMETALLIC COMPOUNDS; PYRIDINES; TEMPERATURE; THYMIDINE MONOPHOSPHATE; TRANSITION ELEMENTS;

EID: 34547679606     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja071076z     Document Type: Article

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