Infections in recipients of a kidney-pancreas transplant;Infecciones en el paciente con trasplante renal y pancreático

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 25, Issue 5, 2007, Pages 345-355

  Cervera, Carlos ^a,b   Moreno, Asunción ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

Infectious complications; Prophylactic measures; Renal and pancreas transplantation

Indexed keywords

AMPHOTERICIN B; ATOVAQUONE; CASPOFUNGIN; COTRIMOXAZOLE; ETHAMBUTOL; FLUCONAZOLE; GANCICLOVIR; LEFLUNOMIDE; MOXIFLOXACIN; PENTAMIDINE; PYRAZINAMIDE; PYRIMETHAMINE SULFADIAZINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; VALACICLOVIR; VORICONAZOLE;

BACTEREMIA; BACTERIAL PNEUMONIA; BK VIRUS; CANDIDIASIS; CAUSE OF DEATH; CRYPTOCOCCUS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; GRAFT FAILURE; HOSPITAL INFECTION; HUMAN; INFECTION PREVENTION; INFECTION RISK; KIDNEY GRAFT REJECTION; KIDNEY PANCREAS TRANSPLANTATION; LEISHMANIASIS; MULTIDRUG RESISTANCE; MYCOSIS; PATIENT MONITORING; PNEUMONIA; POSTOPERATIVE INFECTION; REVIEW; TOXOPLASMOSIS; TUBERCULIN TEST; TUBERCULOSIS; URINARY TRACT INFECTION; VACCINATION; VIRUS INFECTION;

EID: 34547670697     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1016/S0213-005X(07)74299-4     Document Type: Article

References (74)

1. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341:1725-30.
2. Ojo AO, Meier-Kriesche HU, Hanson JA, Leichtman A, Magee JC, Cibrik D, et al. The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation. 2001;71:82-90.
3. Rubin RH, Wolfson JS, Cosimi AB, Tolkoff-Rubin NE. Infection in the renal transplant recipient. Am J Med. 1981;70:405-11.
4. Fishman JA, Rubin RH. Infection in organ-transplant recipients. N Engl J Med. 1998;338:1741-51.
5. Garrido RS, Aguado JM, Díaz-Pedroche C, Len O, Montejo M, Moreno A, et al. A review of critical periods for opportunistic infection in the new transplantation era. Transplantation. 2006;82:1457-62.
6. Gavalda J, Len O, San Juan R, Aguado JM, Fortun J, Lumbreras C, et al. Risk factors for invasive aspergillosis in solid-organ transplant recipients: a case-control study. Clin Infect Dis. 2005;41:52-9.
7. Paduch DA, Barry JM, Arsanjani A, Lemmers MJ. Indication, surgical technique and outcome of orthotopic renal transplantation. J Urol. 2001;166:1647-50.
8. Ayats-Ardite J, Cisneros-Herreros JM, Pérez-Saenz JL, De la Torre-Cisneros. Evaluación de las enfermedades infecciosas en el candidato a un trasplante de órgano sólido. Enferm Infecc Microbiol Clin. 2002;20:448-61.
9. Anonymous. Guidelines for vaccination of solid organ transplant candidates and recipients. Am J Transplant. 2004;4 Suppl 10:160-3.
10. Pumarola Suñe T, Moreno Camacho A, Blanes Julia M. Criterios de selección del donante de órganos respecto a la transmisión de infecciones. Grupo de Estudio de la Infección en el Trasplante (GESITRA). Sociedad española de Enfermedades Infecciosas y Microbiología Clínica, Organización Nacional de Trasplantes (ONT). Med Clin (Barc). 1999;112:711-5.
11. Pfundstein J, Roghmann MC, Schwalbe RS, Qaiyumi SQ, McCarter RJ Jr, Keay S, et al. A randomized trial of surgical antimicrobial prophylaxis with and without vancomycin in organ transplant patients. Clin Transplant. 1999;13:245-52.
12. Saukkonen K, Garland R, Koziel H. Aerosolized pentamidine as alternative primary prophylaxis against Pneumocystis carinii pneumonia in adult hepatic and renal transplant recipients. Chest. 1996;109:1250-5.
13. Meyers B, Borrego F, Papanicolaou G. Pneumocystis carinii pneumonia prophylaxis with atovaquone in trimethoprim-sulfamethoxazole- intolerant orthotopic liver transplant patients: a preliminary study. Liver Transpl. 2001;7:750-1.
14. Torre-Cisneros J, Fortún J, Aguado JM, De la Ca R, Cisneros JM, Gavaldá J, et al. Recomendaciones GESITRA-SEIMC y RESITRA sobre prevención y tratamiento de la infección por citomegalovirus en pacientes trasplantados. Enferm Infecc Microbiol Clin. 2005;23:424-37.
15. Paya C, Humar A, Domínguez E, Washburn K, Blumberg E, Alexander B, et al. Valganciclovir Solid Organ Transplant Study Group. Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant. 2004;4:611-20.
16. Roche Laboratories Inc. Prescribing information Valcyte™ (valganciclovir hydrochloride tablets). Nutley, New Jersey, 2001.
17. Trouillhet I, Benito N, Cervera C, Rivas P, Cofan F, Almela M, et al. Influence of age in renal transplant infections: cases and controls study. Transplantation. 2005;80:989-2.
18. Valera B, Gentil MA, Cabello V, Fijo J, Cordero E, Cisneros JM. Epidemiology of urinary infections in renal transplant recipients. Transplant Proc. 2006;38:2414-5.
19. Cervera C, Linares L, Perelló R, Marco F, Cofán F, Ricart MJ, et al. Cephalosporin resistant gram-negative bacilli infection (ESBL and AMPc) after kidney and kidney-pancreas transplant patients [abstract K-2674]. En: Hooper DC, Hammer SM, Rothman-Denes LB, editors. Program and abstracts of the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy (San Francisco). American Society for Microbiology; 2006 Septiembre, San Francisco(CA), EUA; 2006. p. 350.
20. Linares L, Cervera C, Marco F, Martínez JA, Perelló R, Cofán F, et al. Risk factors for cephalosporin-resistant (ESBL and AMPc producing) gram-negative enteric bacilli infection in renal and kidney-pancreas transplant patients. 16th European Congress of Clinical Microbiology and Infectious Diseases. Nice, France. April 1-4, 2006. Abstract #P923.
21. Muñoz P. Management of urinary tract infections and lymphocele in renal transplant recipients. Clin Infect Dis. 2001;33 Suppl 1:53-7.
22. Kamath NS, John GT, Neelakantan N, Kirubakaran MG, Jacob CK. Acute graft pyelonephritis following renal transplantation. Transpl Infect Dis. 2006;8:140-7.
23. Audard V, Amor M, Desvaux D, Pastural M, Baron C, Philippe R, et al. Acute graft pyelonephritis: a potential cause of acute rejection in renal transplant. Transplantation. 2005;80:1128-30.
24. Rice JC, Peng T, Kuo YF, Pendyala S, Simmons L, Boughton J, et al. Renal allograft injury is associated with urinary tract infection caused by Escherichia coli bearing adherence factors. Am J Transplant. 2006;6:2375-83.
25. Brazda E, Ofner D, Riedmann B, Spechtenhauser B, Margreiter R. The effect of nephrectomy on the outcome of renal transplantation in patients with polycystic kidney disease. Ann Transplant. 1996;1:15-8.
26. Fuller TF, Brennan TV, Feng S, Kang SM, Stock PG, Freise CE. End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation. J Urol. 2005;174:2284-8.
27. Glassman DT, Nipkow L, Bartlett ST, Jacobs SC. Bilateral nephrectomy with concomitant renal graft transplantation for autosomal dominant polycystic kidney disease. J Urol. 2000;164:661-4.
28. Tveit DJ, Hypolite IO, Poropatich RK, Hshieh P, Cruess D, Hawkes CA, et al. Hospitalizations for bacterial pneumonia after renal transplantation in the United States. J Nephrol. 2002;15:255-62.
29. Sileri P, Pursell KJ, Coady NT, Giacomoni A, Berliti S, Tzoracoleftherakis E, et al. A standardized protocol for the treatment of severe pneumonia in kidney transplant recipients. Clin Transplant. 2002;16:450.
30. Cervera C, Agustí C, Ángeles Marcos M, Pumarola T, Cofan F, Navasa M, et al. Microbiologic features and outcome of pneumonia in transplanted patients. Diagn Microbiol Infect Dis. 2006;55:47-54.
31. Berger N, Wirmsberger R, Kafka R, Margreiter C, Ebenbichler C, Stelzmueller I, et al. Infectious complications following 72 consecutive enteric-drained pancreas transplants. Transpl Int. 2006;19:549-57.
32. Dantas SR, Kuboyama RH, Mazzali M, Moretti ML. Nosocomial infections in renal transplant patients: risk factors and treatment implications associated with urinary tract and surgical site infections. J Hosp Infect. 2006;63:117-23.
33. Aguado JM, Herrero JA, Gavalda J, Torre-Cisneros J, Blanes M, Rufi G, et al. Clinical presentation and outcome of tuberculosis in kidney, liver, and heart transplant recipients in Spain. Spanish Transplantation Infection Study Group, GESITRA. Transplantation. 1997;63:1278-86.
34. Muñoz P, Rodríguez C, Bouza E. Mycobacterium tuberculosis infection in recipients of solid organ transplants. Clin Infect Dis. 2005;40:581-7.
35. Singh N, Paterson DL. Mycobacterium tuberculosis infection in solid-organ transplant recipients: impact and implications for management. Clin Infect Dis. 1998;27:1266-77.
36. Richeldi L. Rapid identification of Mycobacterium tuberculosis infection. Clin Microbiol Infect. 2006;12 Suppl 9:34-6.
37. Doucette K, Fishman JA. Nontuberculous mycobacterial infection in hematopoietic stem cell and solid organ transplant recipients. Clin Infect Dis. 2004;38:1428-39.
38. Sagedal S, Nordal KP, Hartmann A, Degre M, Holter E, Foss A, et al. A prospective study of the natural course of cytomegalovirus infection and disease in renal allograft recipients. Transplantation. 2000;70:1166-74.
39. Small LN, Lau J, Snydman DR. Preventing post-organ transplantation cytomegalovirus disease with ganciclovir: a meta-analysis comparing prophylactic and preemptive therapies. Clin Infect Dis. 2006;43:869-70.
40. Ricart MJ, Malaise J, Moreno A, Crespo M, Fernández-Cruz L, Euro-SPK Study Group. Cytomegalovirus: occurrence, severity, and effect on graft survival in simultaneous pancreas-kidney transplantation. Nephrol Dial Transplant. 2005;20 Suppl 2:25-32,62.
41. Huurman VA, Kalpoe JS, Van de LiP, Vaessen N, Ringers J, Kroes AC, et al. Choice of antibody immunotherapy influences cytomegalovirus viremia in simultaneous pancreas-kidney transplant recipients. Diabetes Care. 2006;29:842-7.
42. Ljungman P, Griffiths P, Paya C. Definitions of cytomegalovirus infection and disease in transplant recipients. Clin Infect Dis. 2002;34:1094-7.
43. Fica A, Cervera C, Pérez N, Marcos MA, Ramírez J, Linares L, et al. Immunohistochemically proven CMV-end organ disease in solid-organ transplant patients. Clinical features and usefulness of conventional diagnostic tests. Transpl Infect Dis. En prensa. DOI: 10.1111/j.1399-3062.2007.00220.x
44. Limaye AP, Bakthavatsalam R, Kim HW, Randolph SE, Halldorson JB, Healey PJ, et al. Impact of cytomegalovirus in organ transplant recipients in the era of antiviral prophylaxis. Transplantation. 2006;81:1645-52.
45. Singh N. Late-onset cytomegalovirus disease as a significant complication in solid organ transplant recipients receiving antiviral prophylaxis: a call to heed the mounting evidence. Clin Infect Dis. 2005;40:704-8.
46. Benito N, Ricart MJ, Pumarola T, Marcos MA, Oppenheimer F, Camacho AM. Infection with human herpesvirus 6 after kidney-pancreas transplant. Am J Transplant. 2004;4:1197-9.
47. Benito N, Moreno A, Pumarola T, Marcos MA. Virus del herpes humano tipo 6 y tipo 7 en receptores de trasplantes. Enferm Infecc Microbiol Clin. 2003;21:424-32.
48. Cervera C, Marcos MA, Linares L, Roig E, Benito N, Pumarola T, et al. A prospective survey of human herpesvirus-6 primary infection in solid organ transplant recipients. Transplantation. 2006;82:979-82.
49. Hirsch HH, Steiger J. Polyomavirus BK. Lancet Infect Dis. 2003;3:611-23.
50. Knowles WA, Pipkin P, Andrews N, Vyse A, Minor P, Brown DW, et al. Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol. 2003;71:115-23.
51. Drachenberg CB, Papadimitriou JC. Polyomavirus-associated nephropathy: update in diagnosis. Transpl Infect Dis. 2006;8:68-75.
52. Hirsch HH. BK virus: opportunity makes a pathogen. Clin Infect Dis. 2005;41:354-60.
53. Hirsch HH, Knowles W, Dickenmann M, Passweg J, Klimkait T, Mihatsch MJ, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med. 2002;347:488-96.
54. Gupta G, Shapiro R, Thai N, Randhawa PS, Vats A. Low incidence of BK virus nephropathy after simultaneous kidney pancreas transplantation. Transplantation. 2006;82:382-8.
55. Trofe J, Gaber LW, Stratta RJ, Shokouh-Amiri MH, Vera SR, Alloway RR, et al. Polyomavirus in kidney and kidney-pancreas transplant recipients. Transpl Infect Dis. 2003;5:21-8.
56. Haririan A, Ramos ER, Drachenberg CB, Weir MR, Klassen DK. Polyomavirus nephropathy in native kidneys of a solitary pancreas transplant recipient. Transplantation. 2002;73:1350-3.
57. Trofe J, Hirsch HH, Ramos E. Polyomavirus-associated nephropathy: update of clinical management in kidney transplant patients. Transpl Infect Dis. 2006;8:76-85.
58. Josephson MA, Williams JW, Chandraker A, Randhawa PS. Polyomavirus-associated nephropathy: update on antiviral strategies. Transpl Infect Dis. 2006;8:95-101.
59. Moreno A, Cervera C, Rovira M, Uriburu C, Almela M, De la Cámara R, et al, and the members of RESITRA Study Group (Spain) [abstract K-1564]. Bloodstream Infection In Transplant Patients In Spain. En: Hooper DC, Hammer SM, Rothman-Denes LB, editors. Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy (Washington). American Society for Microbiology; 2005 Diciembre 16-19. Washington, EUA; p. 356.
60. Nath DS, Kandaswamy R, Gruessner R, Sutherland DE, Dunn DL, Humar A. Fungal infections in transplant recipients receiving alemtuzumab. Transplant Proc. 2005;37:934-6.
61. Safdar N, Slattery WR, Knasinski V, Gangnon RE, Li Z, Pirsch JD, et al. Predictors and outcomes of candiduria in renal transplant recipients. Clin Infect Dis. 2005;40:1413-21.
62. Husain S, Wagener MM, Singh N. Cryptococcus neoformans infection in organ transplant recipients: variables influencing clinical characteristics and outcome. Emerg Infect Dis. 2001;7:375-81.
63. Singh N, Alexander BD, Lortholary O, Dromer F, Gupta KL, John GT, et al. Cryptococcus neoformans in Organ Transplant Recipients: Impact of Calcineurin-Inhibitor Agents on Mortality. J Infect Dis. 2007;195:756-64.
64. Singh N, Lortholary O, Alexander BD, Gupta KL, John GT, Pursell K, et al. Allograft loss in renal transplant recipients with cryptococcus neoformans associated immune reconstitution syndrome. Transplantation. 2005;80:1131-3.
65. Tharayil John G, Shankar V, Talaulikar G, Mathews MS, Abraham Abraham M, Punnakuzhathil Thomas P, et al. Epidemiology of systemic mycoses among renal-transplant recipients in India. Transplantation. 2003;75:1544-51.
66. Panackal AA, Dahlman A, Keil KT, Peterson CL, Mascola L, Mirza S, et al. Outbreak of invasive aspergillosis among renal transplant recipients. Transplantation. 2003;75:1050-3.
67. Altiparmak MR, Apaydin S, Trablus S, Serdengecti K, Ataman R, Ozturk R, et al. Systemic fungal infections after renal transplantation. Scand J Infect Dis. 2002;34:284-8.
68. Gustafson TL, Schaffner W, Lavely GB, Stratton CW, Johnson HK, Hutcheson RH Jr. Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy. J Infect Dis. 1983;148:230-8.
69. Paterson DL, Singh N. Invasive aspergillosis in transplant recipients. Medicine (Baltimore). 1999;78:123-38.
70. Gavaldá J, Ruiz I, MICOMED, GESITRA, SEIMC. Recomendaciones para el tratamiento de la infección por Aspergillus spp. Enferm Infecc Microbiol Clin. 2003;21:571-8.
71. Singh N, Limaye AP, Forrest G, Safdar N, Muñoz P, Pursell K, et al. Combination of voriconazole and caspofungin as primary therapy for invasive aspergillosis in solid organ transplant recipients: a prospective, multicenter, observational study. Transplantation. 2006;81:320-6.
72. Trullas JC, Cervera C, Benito N, De la Be J, Agustí C, Rovira M, et al. Invasive pulmonary aspergillosis in solid organ and bone marrow transplant recipients. Transplant Proc. 2005;37:4091-3.
73. Renoult E, Georges E, Biava MF, Hulin C, Frimat L, Hestin D, et al. Toxoplasmosis in kidney transplant recipients: report of six cases and review. Clin Infect Dis. 1997;24:625-34.
74. Basset D, Faraut F, Marty P, Dereure J, Rosenthal E, Mary C, et al. Visceral leishmaniasis in organ transplant recipients: 11 new cases and a review of the literature. Microbes Infect. 2005;7:1370-5.