Hepatic injury induces contrasting response in liver and kidney to chemicals that are metabolically activated: Role of male sex hormone

Toxicology and Applied Pharmacology

Volumn 223, Issue 1, 2007, Pages 56-65

  Kim, Young C ^a   Yim, Hye K ^a   Jung, Young S ^a   Park, Jae H ^a   Kim, Sung Y ^b  

^a Seoul National University   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

Liver injury; Nephrotoxicity; Renal Cyp; Sex difference; Testosterone

Indexed keywords

4 NITROANISOLE DEMETHYLASE; 4 NITROPHENOL HYDROXYLASE; AMINOPYRINE N DEMETHYLASE; CARBON TETRACHLORIDE; CYTOCHROME P450; KIDNEY ENZYME; PARACETAMOL; SEX HORMONE; TESTOSTERONE PROPIONATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; HORMONE ACTION; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; LIVER INJURY; LIVER METABOLISM; LIVER TOXICITY; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PARTIAL HEPATECTOMY; SEX DIFFERENCE; TARGET ORGAN; TOXIC HEPATITIS; XENOBIOTIC METABOLISM;

ACETAMINOPHEN; AMINOPYRINE N-DEMETHYLASE; ANIMALS; BIOTRANSFORMATION; CARBON TETRACHLORIDE; CYTOCHROME P-450 CYP2E1; FEMALE; HEPATECTOMY; HEPATITIS, TOXIC; HEPATOCYTES; KIDNEY; LIVER; MALE; MICE; MICE, INBRED ICR; NECROSIS; ORCHIECTOMY; ORGAN SPECIFICITY; OXIDOREDUCTASES, O-DEMETHYLATING; SEX FACTORS; TESTOSTERONE;

MUS;

EID: 34547665624     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.05.009     Document Type: Article

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