Age dependent differential effects of cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats

Archives of Toxicology

Volumn 71, Issue 11, 1997, Pages 696-702

  Eke, Benay C ^a   Vural, Nevin ^a   Işcan, Mümtaz ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Cigarette smoke; Glutathione; Glutathione S transferases; Lipid peroxidation; Monooxygenases

Indexed keywords

CIGARETTE SMOKE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; UNSPECIFIC MONOOXYGENASE;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; BODY WEIGHT; ENZYME INDUCTION; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; LIVER; LUNG; MALE; RATS; TOBACCO SMOKE POLLUTION; XENOBIOTICS;

ANIMALIA;

EID: 0030821016     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050447     Document Type: Article

References (51)

1. Bilimoria MH, Ecobichon DJ (1992) Protective antioxidant mechanism in rat and guinea pig tissues challenged by acute exposure to cigarette smoke. Toxicology 72: 131-134
2. Bishayee S, Balasubramanian AS (1971) Lipid peroxide formation in rat brain. J Neurochem 18: 909-920
3. Bjelogrlic N, İşcan M, Raunio H, Pelkonen O, Vahakangas K (1989) Benzo(a)pyrene DNA-adducts and monooxygenase activities in mice treated with benzo(a)pyrene, cigarette smoke or cigarette smoke condensate. Chem Biol Interact 70: 51-61
4. Bray TM, Taylor CG (1993) Tissue glutathione nutrition and oxidative stress. Can J Physiol Pharmacol 71: 746-751
5. Burke MD, Thompson S, Elcombe ER, Halpent J, Heaparanta T, Mayer RT (1985) Ethoxy, pentoxy, and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol 42: 585-591
6. Carlstedt-Duke JMB, Elfsrom G, Hogberg B, Gustafsson JA (1979) Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine independence. Cancer Res 39: 4653-4656
7. Church DF, Pryor WA (1985) Free radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 64: 111-126
8. Cochin J, Axelrod J (1959) Biochemical and pharmacological changes in the rat following chronic administration of morphine, nalorphine and normorphine. J Pharmacol Exp Ther 125: 105-110
9. Coecke S, Vandenberghe Y, Callaerts A, Sonck W, Verleye G, Van Bezooijen CFA, Vercruysse A, Rogiers V (1990) Hepatic cytosolic glutathione S-transferase activities in ageing brown Norway rats. Importance of sex differences and phenobarbital treatment for studies of ageing. Mech Ageing Dev 55: 189-198
10. Eke BC (1992) The investigation of the effects of cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats. Thesis. Ankara University, Ankara
11. Eke BC, Vural N, İşcan M (1996) Combined effects of ethanol and cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats. Chem Biol Interact, 102: 155-167
12. Farooqui MYH, Day WW, Zamorano DM (1987) Glutathione and lipid peroxidation in the aging rats. Comp Biochem Physiol 88B: 177-180
13. Gasiewicz TA, Ness WC, Rucci G (1984) Ontogeny of the cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, lung and thymus. Biochem Biophys Res Commun 118: 183-190
14. Gonzalez F (1989) The molecular biology of cytochrome P450s. Pharmacol Rev 40: 243-288
15. Guengerich FP, Dannon GA, Wright ST, Martin MV, Kaminsky LS (1982) Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isoenzymes isolated from rats treated with phenobarbital and β-naphthoflavone. Biochemistry 21: 6019-6030
16. Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139
17. Horbach GJMJ, Van Hasten JG, Van Bezooijen CFA (199a) The influence of age on the inducibility of rat liver cytochrome P4501 A1 (CYP1A1) and P4501A2 (CYP1A2) mRNAs. Mutat Res 237: 117-121
18. Horbach GJMJ, Van Hasten JG, Van Bezooijen CFA (1990b) The influence of ageing on the induction of the mRNAs of rat liver cytochromes P450IIB1 and P450IIB2. Biochem Pharmacol 40: 529-533
19. IARC (1986) Tobacco somking. In: Monographs on the evaluation of the carcinogen risk to humans, vol 38, IARC, Lyon
20. Imai Y, Ito A, Sato R (1966) Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. J Biochem 60: 417-428
21. Imanishi H, Nakai T, Abe T, Takino T (1985) Glutathione metabolism in red cell aging. Mech Ageing. Dev 32: 57-62
22. İşcan M (1987) Studies on the activities of drug metabolizing enzymes in liver 10000 g supernatant fraction and Ca aggreated microsomes of the guinea pig. (Turk) J Biochem 12: 1-18
23. İşcan M, Arinç E, Vural N, İşcan MY (1984) In vivo effects of 3-methylcholanthrene, phenobarbital, pyrethrum and 2,4,5-T isooctylester on liver, lung and kidney microsomal mixed function oxidase system of guinea pig: a comparative study. Comp Biochem Physiol 77C: 177-190
24. İşcan M, Çoban T, Eke BC (1992) Responses of hepatic xenobiotic metabolizing enzymes of mouse, rat and guinea pig to nickel. Pharmacol Toxicol 71: 434-442
25. Kamataki T, Maeda K, Shimada M, Kitani K, Nagai T, Kato R (1985) Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes form male and female rats. J Pharmacol Exp Ther 233: 222-228
26. Ketterer B, Meyer DJ (1989) Glutathione transferases: a possible role in the detoxication and repair of DNA and lipid hydroperoxides. Mutat Res 214: 33-40
27. Ketterer B, Mulder GJ (1990) Glulathione conjugation. In: Mulder GJ (ed) Conjugation reactions in drug metabolism, Taylor and Francis, London, pp 307-364
28. Khanduja KL, Gupta MP, Dogra SC, Pathak CM (1985) Effect of cigarette smoke inhalation on certain pulmonary and hepatic drue metabolizing enzymes in rat and mouse. Ind J Exp Biol 23: 51-59
29. Klinger W (1990) Biotransformation of xenobiotics during ontogenetic development. In: Ruckpaul K, Rein H (eds) Frontiers in biotransformation, vol 2. Akademie-Verlag, Berlin, pp 113-149
30. Klotz AV, Stegeman JJ, Walsh C (1984) An alternative 7-ethoxyresorutin O-deethylase activity assay: a continuous visible spectrophotometric method for measurement of the cytochrome P-450 monooxygenase activity. Anal Biochem 140: 138-145
31. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
32. Mannervik B, Danielson UH (1988) Glutathione transferases structures and catalytic activity. CRC Crit Rev Biohem 23: 283-337
33. Mannervik B, Awasthi YC, Board PG, Hayes JD, Di İlio C, Ketterer B, Listowsky I, Morgenstern R, Muramatsu M, Pearson WR, Pickett CB, Sato K, Widersten M, Wolf CR (1992) Nomenclature for human glutathione transferases. Biochem J 282: 305-308
34. Meyer DJ, Coles B, Pemble SE, Gilmore KS, Fraser GM, Ketterer B (1991) Theta, a new class of glutathione transferases purified from rat and man. Biochem J 274: 409-414
35. Morgenstern R, Lundqvist G, Andersson G, Balk L, De Pierre JW (1984) The distribution of microsomal glutathione transferase among different organelles, different organs and different organism. Biochem Pharmacol 3: 3609-3614
36. Nash T (1953) The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Bochem J 55: 416-421
37. Nebert DW, Nelson DR, Coon MJ, Estabrook RW, Feyeresien R, Fujii-Kuriyama Y, Gonzales FJ, Guengerich FP, Gunsalus IC, Johnson EF, Loper JC, Sato R, Waterman MR, Waxman DJ (1991) The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol 10: 1-14
38. Nedeleva MJ, Gut I (1994) P450 in the rat and man: methods ov investigation, substrate specificities and relevance to cancer. Xenobiotica 24: 1151-1175
39. Netter KJ, G. Seidel G (1964) An adaptively stimulated O-demethylating system in rat liver microsomes and its kinetic properties. J Pharmacol Exp Ther 146: 61-65
40. Paolini M, Mesirca R, Pozelti L, Biagi GL, Cantelli-Forti G (1992) Selective induction of murine liver cytochrome P450 IIBI by halogenated hydrocarbons. Toxicol Environ Chem 36: 235-249
41. Parke DV, Ioannides C, Lewis DFV (1991) The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals. Can J Physiol Pharmacol 69: 537-549
42. Rogiers V, Coecke S, Vandenberghe Y, Morel F, Callaerts A, Verleye G, Van Bezooijen CFA, Guillouzo A, Vercruysse A (1991) Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver. Biochem Pharmacol 42: 491-498
43. Sagai M, Ichinose T, Oda H, Kubota K (1982) Studies on biochemical effect of nitrogen dioxide. II. Changes of the protective systems in rat lungs and lipid peroxidation by acute exposure. J Toxicol Enviorn Health 9: 153-164
44. Sedlak J, Lindsay RH (1968) Estimation of total protein-bound and non protein sulfhydryl groups in tissue with Ellmann's reagent. Anal Biochem 25: 192-205
45. Spearman ME, Leibman KC (1984) Effects of aging on hepatic and pulmonary glutathione S-transferase activities in male and female Fisher 344 rats. Biochem Pharmacol 33: 1309-1313
46. Tan KH, Meyer DJ, Belin J, Ketterer B (1984) Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of phospholipase A2. Biochem J 220: 243-252
47. Vos RME, Bladeren PJ (1990) Glutathione S-transferases in relation to their role in the biotransformation of xenobiotics. Chem Biol Interact 76: 241-265
48. Warner HR (1994) Superoxide dismutase, aging and degenerative disease. Free Radic Biol Med 17: 249-258
49. Waxman DJ, Dannan GA, Guengerich FP (1985) Regulation of rat hepatic cytochrome P450: age-dependent expression, hormonal imprinting and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24: 4409-4417
50. Wills ED (1966) Mechanism of lipid peroxide formation in animal tissues. Biochem J 99: 667-676
51. Wills ED (1969) Lipid peroxide formation in microsomes. Relationship of hydroxylation to lipid peroxide formation. Biochem J 113: 333-341