Effects of 7-hydroxy-3-methoxycadalene on cell cycle, apoptosis and protein translation in A549 lung cancer cells

BioFactors

Volumn 29, Issue 2-3, 2007, Pages 67-75

  Jin, Hua ^a   Kim, Hyun Woo ^a   Xu, Cheng Xiong ^a   Kwon, Jung Taek ^a   Hwang, Soon Kyung ^a   Lee, Eun Sun ^a   Chang, Seung Hee ^a   Park, Sung Jin ^a   Noh, Mi Suk ^a   Woo, Min Ah ^a   Yu, Kyeong Nam ^a   Lee, Hu Jang ^b   Choi, Joon Weon ^c   Choi, Don Ha ^c   Cho, Myung Haing ^a  

^a Seoul National University   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Korea Forest Research Institute   (South Korea)

Author keywords

Apoptosis; Cadalene; Cell cycle; Lung cancer; Protein translation

Indexed keywords

7 HYDROXY 3 METHOXYCADALENE; ANTINEOPLASTIC AGENT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SESQUITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; TRANSLATION INITIATION;

MUS; ZELKOVA SERRATA;

EID: 34547663066     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.552029206     Document Type: Article

References (29)

1. American Council on Science and Health, Environmental tobacco smoke: health risk or health type? American Council on Science and Health, New York, 1999, 1-38.
2. P.J. Coffer, J. Jin and J.R. Woodgett, Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation, Biochem J 335 (1998), 1-13.
3. O. Coqueret, New roles for p21 and p27 cell-cycle inhibitor: a function for each cell compartment? Trends Cell Biol 13 (2003), 65-70.
4. S. Cory, D.C. Huang and J.M. Adams, The Bcl-2 family: roles in cell survival and oncogenesis, Oncogene 22 (2003), 8590-8607.
5. P.L. Dahia, R.C. Aguiar, J. Alberta, J.B. Kum, S. Caron, H. Sill, D.J. Marsh, J. Ritz, A. Freedman, C. Stiles and C. Eng, PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanism haematological malignancies, Hum Mol Genet 8 (1999), 185-193.
6. O. David, Akt and PTEN: New diagnostic markers of non-small cell lung cancer? J Cell Mol Med 5 (2001), 430-433
7. A. Fortin, S.P. Cregan, J.G. MacLaurin, N. Kushwaha, E.S. Hickman, C.S. Thompson, A. Hakim, P.R. Albert, F. Cecconi, K. Helin, D.S. Park and R.S. Slack, APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death, J Cell Biol 155 (2001), 207-216.
8. A.C. Gingras, B. Raught and N. Sonenberg, eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation, Annu Rev Biochem 68 (1999), 913-963.
9. T. Hideshima, L. Catley, H. Yasui, K. Ishitsuka, N. Raje, C. Mitsiades, K. Podar, N.C. Munshi, D. Chauhan, P.G. Richardson and K.C. Anderson, Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells, Blood 107 (2006), 4053-4062.
10. S.L. Iverson and S. Orrenius, The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis, Arch, Biochem Biophys 423 (2004), 37-46.
11. A. Jemal, T. Murray, E. Ward, A. Samuels, R.C. Tiwari, A. Ghafoor, E.J. Feuer and M.J. Thun, Cancer Statistics, CA-Cancer J Clin 55 (2005), 10-30.
12. H. Jin, T.H. Kim, S.K. Hwang, S.H. Chang, H.W. Kim, H.K. Anderson, H.W. Lee, K.H. Lee, N.H. Colburn, H.S. Yang, M.H. Cho and C.S. Cho, Aerosol delivery of urocanic acid-modified chitosan (UAC)/programmed cell death 4 (PDCD4) complex regulated apoptosis, cell cycle and angiogenesis in lungs of K-ras null mice, Mol Cancer Ther 5 (2006), 1041-1049.
13. E.S. Kandel and N. Hay, The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB, Exp Cell Res 253 (1999), 210-229.
14. J.H. Kim, H.J. Lee, G.S. Kim, D.H. Choi, S.S. Lee, J.K. Kang, C. Chae, N.W. Paik and M.H. Cho, Inhibitory effects of 7-Hydroxy-3-methoxycadalene (cadalene) on 4-(methylnitosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice, Cancer Lett 213 (2004), 139-145.
15. J.H. Kim, H.J. Lee, S.C. Yeon, D.H. Choi, S.S. Lee, J.K. Kang, C. H. Chae, N.W. Paik, K.H. Lee and M.H. Cho, Antioxidative effects of 7-hydroxy-3-methoxy-cadalene extracted from zelkova serrata on 4-(methylinitros amino)-1-(3-pyridyl)-1-butanone-induced oxidative stress in A/J mice, Phytother Res 18 (2004), 425-427.
16. H.W. Kim, I.K. Park, C.S. Cho, K.H. Lee, G.J. Beck, N.H. Colburn and M.H. Cho, Aerosol gene delivery of glucosylated polyethyleneimine (GPEI)/PTEN complex suppresses Akt downstream pathways in the lung of K-ras null mice, Cancer Res 64 (2004), 7971-7976.
17. H. Kohno, M. Taima, T. Sumida, Y. Azuma, H. Ogawa and T. Tanaka, Inhibitory effect of mandarin juice rich in betacryptoxanthin and hesperidin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary tumorigenesis in mice, Cancer Lett 174 (2001), 141-150.
18. S.S. Lee, H.J. Lee, H.Y. Kang and D.H. Choi, Studies on biological activity of wood extractives (I): antimicrobial and antioxidative activity of heartwood extractives, FRI J Forest Sci 61 (1999), 82-89.
19. S.S. Lee, H.J. Lee, H.Y. Kang and D.H. Choi, Studies on biological activity of wood extractives (II): antimicrobial and antioxidative activity of heartwood extractives, Korean Wood Sci Techol 28 (2000), 32-41.
20. L. Li, M. Takahashi, C. Miliaresis, M.P. Myers, N. Tonks and R. Parsons, The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene, Cancer Res 58 (1998), 5667-5672.
21. T.T. Nguyen Tu, S. Derenne, C. Largeau, A. Mariotti, H. Bocherens and D. Pons, Effects of fungal infection on lipid extract composition of higher plant remains: comparison of shoots of a Cenonmanian conifer, uninfected and infected by extinct fungi, Org Geochem 31 (2000), 1743-1754.
22. K.M. Nicholson and N.G. Anderson, The protein kinase B/Akt signaling pathway in human malignancy, Cell Signal 14 (2002), 381-395.
23. T. Schmelzle and M.N. Hall, TOR, a central controller of cell growth, Cell 103 (2000), 253-262.
24. V. Stambolic, A. Suzuki, J.L. de la Pompa JL, G.M. Brothers, C. Mirtsos, T. Sasaki, J. Ruland, J.M. Penninger, D.P. Siderovski and T.W. Mak, Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN, Cell 95 (1998), 29-39.
25. J.M. Tang, Q.Y. He, R.X. Guo and X.J. Chang, Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis, Lung Cancer 51 (2006), 181-191.
26. A.M. Tehrani, S.K. Hwang, T.H. Kim, C.S. Cho, H. Jin,W.S. Nah, J.T. Kwon, J.S. Kim, S.H. Chang, K.N. Yu, S.J. Park, D.R. Bhandari, K.H. Lee, G.H. An, G.R. Beck Jr and M.H. Cho, Aerosol delivery of Akt controls protein translation in the lungs of dual luciferase reporter mice, Gene Ther (2007), 451-458.
27. I. Vivanco and C.L. Sawyers, The phosphatidylinositol 3-kinase AKT pathway in human cancer, Nat Rev Cancer 2 (2002), 489-501.
28. A.J. Waskiewicz, A. Flynn, C.G. Proud and J.A. Cooper, Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2, EMBO J 16 (1997), 1909-1920.
29. X. Wu, K. Senechal, M.S. Neshat, Y.E. Whang and C.L. Sawyers, The PTEN/MMAC tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway, Proc Natl Acad Sci USA 95 (1998), 15587-15591.