Neural synchrony in schizophrenia: From networks to new treatments

Schizophrenia Bulletin

Volumn 33, Issue 4, 2007, Pages 848-852

  Ford, Judith M ^a,b   Krystal, John H ^a,b   Mathalon, Daniel H ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Neural synchrony; Schizophrenia; Translational neuroscience

Indexed keywords

COGNITIVE DEFECT; CONFERENCE PAPER; CORTICAL SYNCHRONIZATION; GAMMA RHYTHM; HUMAN; NERVE CELL NETWORK; NERVE CONDUCTION; NEUROANATOMY; NEUROCHEMISTRY; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOPHRENIA; SYNAPTIC TRANSMISSION; THETA RHYTHM;

BRAIN; DOPAMINE; ELECTROENCEPHALOGRAPHY; EVENT-RELATED POTENTIALS, P300; HUMANS; NERVE NET; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

EID: 34547653646     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbm062     Document Type: Conference Paper

References (59)

1. Singer W. Neuronal synchrony: a versatile code for the definition of relations? Neuron. 1999;24:49-65.
2. Hebb DO. Organization of Behavior: A Neuropsychological Theory. New York, NY: John Wiley and Sons; 1949.
3. Hopfield JJ, Brody CD. What is a moment? "Cortical" sensory integration over a brief interval. Proc Natl Acad Sci USA. 2000;97:13919-13924.
4. Miltner W, Braun C, Arnold M, Witte H, Taub E. Coherence of gamma-band EEG activity as a basis for associative learning. Nature. 1999;397:434-436.
5. Fuster JM. The prefrontal cortex-an update: time is of the essence. Neuron. 2001;30:319-333.
6. Singer HS, Reiss AL, Brown JE, et al. Volumetric MRI changes in basal ganglia of children with Tourette's syndrome. Neurology. 1993;43:950-956.
7. Varela F, Lachaux JP, Rodriguez E, Martinerie J. The brainweb: phase synchronization and large-scale integration. Nat Rev Neurosci. 2001;2:229-239.
8. Bastiaansen MCM, Hagoort P. Oscillatory brain dynamics during language comprehension. In: Klimesch W, Neuper C, eds. Event-Related Dynamics of Brain Oscillations Progress in Brain Research Series. Amsterdam, The Netherlands: Elsevier; 2006.
9. Buzsaki G. Large-scale recording of neuronal ensembles. Nat Neurosci. 2004;7:446-451.
10. Tallon-Baudry C, Bertrand O, Delpuech C, Pernier J. Stimulus specificity of phase-locked and non-phase-locked 40 Hz visual responses in human. J Neurosci. 1996;16:4240-4249.
11. Spencer KM, Nestor PG, Perlmutter R, et al. Neural synchrony indexes disordered perception and cognition in schizophrenia. Proc Natl Acad Sci USA. 2004;101:17288-17293.
12. Fries P, Reynolds J, Rorie A, Desimone R. Modulation of oscillatory neuronal synchronization by selective visual attention. Science. 2001;291:1560-1563.
13. Pinto DJ, Brumberg JC, Simons DJ. Circuit dynamics and coding strategies in rodent somatosensory cortex. J Neurophysiol. 2000;83:1158-1166.
14. Lisman J. The theta/gamma discrete phase code occurring during the hippocampal phase precession may be a more general brain coding scheme. Hippocampus. 2005;15:913-922.
15. Hughes SW, Lorincz M, Cope DW, et al. Synchronized oscillations at alpha and theta frequencies in the lateral geniculate nucleus. Neuron. 2004;42:253-268.
16. Blatow M, Rozov A, Katona I, et al. A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron. 2003;38:805-817.
17. Konig P, Engel AK, Singer W. Integrator or coincidence detector? The role of the cortical neuron revisited. Trends Neurosci. 1996;19:130-137.
18. Canolty RT, Edwards E, Dalal SS, et al. High gamma power is phase-locked to theta oscillations in human neocortex. Science. 2006;313:1626-1628.
19. Lisman JE, Otmakhova NA. Storage, recall, and novelty detection of sequences by the hippocampus: elaborating on the SOCRATIC model to account for normal and aberrant effects of dopamine. Hippocampus. 2001;11:551-568.
20. Bland BH, Oddie SD. Theta band oscillation and synchrony in the hippocampal formation and associated structures: the case for its role in sensorimotor integration. Behav Brain Res. 2001;127:119-136.
21. Ritz R, Sejnowski TJ. Synchronous oscillatory activity in sensory systems: new vistas on mechanisms. Curr Opin Neurobiol. 1997;7:536-546.
22. von Krosigk M, Bal T, McCormick DA. Cellular mechanisms of a synchronized oscillation in the thalamus. Science. 1993;261:361-364.
23. Buzsaki G, Csicsvari J, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cereb Cortex. 2002;12:893-899.
24. Cooper DC. The significance of action potential bursting in the brain reward circuit. Neurochem Int. 2002;41:333-340.
25. Larson J, Wong D, Lynch G. Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation. Brain Res. 1986;368:347-350.
26. Morgan SL, Teyler TJ. VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo. J Neurophysiol. 1999;82:736-740.
27. Jackson ME, Homayoun H, Moghaddam B. NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc Natl Acad Sci USA. 2004;101:8467-8472.
28. Grunze HCR, Rainnie DG, Hasselmo ME, et al. NMDA-dependent modulation of CA1 local circuit inhibition. J Neurosci. 1996;16:2034-2043.
29. Yonezawa Y, Kuroki T, Kawahara T, Tashiro N, Uchimura H. Involvement of gamma-aminobutyric acid neurotransmission in phencyclidine-induced dopamine release in the medial prefrontal cortex. Eur J Pharmacol. 1998;341:45-56.
30. Krystal JH, D'Souza DC, Mathalon D, Perry E, Belger A, Hoffman R. NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology. 2003;169:215-233.
31. Castner SA, Williams GV. Tuning the engine of cognition: a focus on NMDA receptor interactions in prefrontal cortex. Brain Cogn. 2007;63:94-122.
32. Haenschel C, Baldeweg T, Croft RJ, Whittington M, Gruzelier J. Gamma and beta frequency oscillations in response to novel auditory stimuli: a comparison of human electroencephalogram (EEG) data with in vitro models. Proc Natl Acad Sci USA. 2000;97:7645-7650.
33. Porjesz B, Almasy L, Edenberg HJ, et al. Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci USA. 2002;99:3729-3733.
34. Whittington MA, Traub RD, Jefferys JG. Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation. Nature. 1995;373:612-615.
35. Peters Y, Barnhardt NE, O'Donnell P. Prefrontal cortical up states are synchronized with ventral tegmental area activity. Synapse. 2004;52:143-152.
36. Searles JS, Alterman AI. Differential attrition rates in alcohol abusing and nonabusing schizophrenic inpatients - a methodological note. Alcohol Clin Exp Res. 1992;16:705-707.
37. O'Donnell P. Dopamine gating of forebrain neural ensembles. Eur J Neurosci. 2003;17:429-435.
38. Lavin A, Grace AA. Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. Neuroscience. 2001;104:335-346.
39. Williams GV, Goldman-Rakic PS. Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature. 1995;376:572-575.
40. Seamans JK, Yang CR. The principal features and mechanisms of dopamine modulation in the prefrontal cortex. Prog Neurobiol. 2004;74:1-58.
41. Wang GJ, Volkow ND, Chang L, et al. Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence. Am J Psychiatry. 2004;161:242-248.
42. Phillips WA, Silverstein SM. Convergence of biological and psychological perspectives on cognitive coordination in schizophrenia. Behav Brain Sci. 2003;26:65-82 discussion 82-137.
43. Kraepelin E. Dementia Praecox and Paraphrenia. Edinburgh, Scotland: E. & S. Livingstone; 1919.
44. Kwon JS, O'Donnell BF, Wallenstein GV, et al. Gamma frequency-range abnormalities to auditory stimulation in schizophrenia. Arch Gen Psychiatry. 1999;56:1001-1005.
45. Ford JM, Mathalon DH. Corollary discharge dysfunction in schizophrenia: can it explain auditory hallucinations? Int J Psychophysiol. 2005;58:179-189.
46. Koukkou M, Federspiel A, Braker E, et al. An EEG approach to the neurodevelopmental hypothesis of schizophrenia studying schizophrenics, normal controls and adolescents. J Psychiatr Res. 2000;34:57-73.
47. Howard MW, Rizzuto DS, Caplan JB, et al. Gamma oscillations correlate with working memory load in humans. Cereb Cortex. 2003;13:1369-1374.
48. Lee J, Park S. Working memory impairments in schizophrenia: a meta-analysis. J Abnorm Psychol. 2005;114:599-611.
49. Demiralp T, Basar E. Theta rhythmicities following expected visual and auditory targets. Int J Psychophysiol. 1992;13:147-160.
50. Basar E, Demiralp T, Schurmann M, Basar-Eroglu C, Ademoglu A. Oscillatory brain dynamics, wavelet analysis, and cognition. Brain Lang. 1999;66:146-183.
51. Basar E, Schurmann M, Demiralp T, Basar-Eroglu C, Ademoglu A. Event-related oscillations are 'real brain responses'-wavelet analysis and new strategies. Int J Psychophysiol. 2001;39:91-127.
52. Ford JM. Schizophrenia: the broken P300 and beyond. Psychophysiology. 1999;36:667-682.
53. Kang K, Williams LM, Hermens D, Gordon E. Neurophysiological markers of contextual processing: the relationship between P3b and gamma synchrony and their modulation by arousal, performance and individual differences. Brain Res Cogn Brain Res. 2005;25:472-483.
54. Krystal JH, Karper LP, Seibyl JP, et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 1994;51:199-214.
55. Javitt DC, Steinschneider M, Schroeder CE, Arezzo JC. Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation: implications for schizophrenia. Proc Natl Acad Sci USA. 1996;93:11962-11967.
56. Coyle JT. The glutamatergic dysfunction hypothesis for schizophrenia. Harv Rev Psychiatry. 1996;3:241-253.
57. Benes FM, Vincent SL, Marie A, Khan Y. Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience. 1996;75:1021-1031.
58. Lewis DA. GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia. Brain Res Brain Res Rev. 2000;31:270-276.
59. Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci. 2005;6:312-324.