Amidates as leaving groups: Structure/reactivity correlation of the hydroxide-dependent E1cB-like breakdown of carbinolamides in aqueous solution

Journal of Organic Chemistry

Volumn 72, Issue 16, 2007, Pages 6075-6083

  Tenn III, William J ^a   Murphy, John L ^a   Bim Merle, Jessica K ^a   Brown, Jason A ^a   Junia, Adam J ^a   Price, Malea A ^a   Nagorski, Richard W ^a  

^a ILLINOIS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER CATALYSIS; HYDROXYL GROUP; LEAVING GROUPS; RATE-LIMITING BREAKDOWN;

ALDEHYDES; CATALYST ACTIVITY; DEPROTONATION; DERIVATIVES; PH; REACTION RATES; SOLUTIONS;

AMIDES;

ALDEHYDE; ETOMIDATE; HYDROXIDE; HYDROXYL GROUP; N (HYDROXYMETHYL)BENZAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CATALYSIS; KINETICS; PKA; PROTON TRANSPORT; REACTION ANALYSIS;

EID: 34547645282     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo070603u     Document Type: Article

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