Essential features of the catalytic core of peptidyl-α-hydroxyglycine α-amidating lyase

Biochemistry

Volumn 41, Issue 41, 2002, Pages 12384-12394

  Kolhekar, Aparna S ^a,b   Bell, Joseph ^a   Shiozaki, Eric N ^a,c   Jin, Lixian ^a,d   Keutmann, Henry T ^a,e   Hand, Tracey A ^a,d   Mains, Richard E ^a   Eipper, Betty A ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b SAIC FREDERICK INC   (United States)

^c PRINCETON UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVE PEPTIDES;

CATALYSIS; CHEMICAL ANALYSIS; MUTAGENESIS; ORGANIC COMPOUNDS;

ENZYMES;

ALPHA AMIDATING ENZYME; ASPARTIC ACID; CHELATING AGENT; CYSTEINE; GLUTAMIC ACID; HISTIDINE; METAL ION; SKATOLE; TRYPSIN; ZINC;

AMIDATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PURIFICATION; ENZYME RELEASE; ENZYME STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

AMIDINE-LYASES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CHO CELLS; COPPER; CRICETINAE; DISULFIDES; EDETIC ACID; ENZYME INHIBITORS; EXONS; HUMANS; HYDROLYSIS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; PROTEIN FOLDING; RATS; TRYPSIN; ZINC;

EID: 0037108087     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0260280     Document Type: Article

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