Kinetics and Mechanism of Hydrolysis of N-Acyloxymethyl Derivatives of Azetidin-2-one

Journal of Organic Chemistry

Volumn 69, Issue 10, 2004, Pages 3359-3367

  Valente, Emília ^a   Gomes, José R B ^b   Moreira, Rui ^a   Iley, Jim ^c  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c OPEN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; DERIVATIVES; ESTERS; HYDROLYSIS; MOLECULAR STRUCTURE; PH EFFECTS; REACTION KINETICS;

NUCLEOPHILIC ATTACK; PROTONATION;

CATALYST ACTIVITY;

(2 OXOAZETIDIN 1 YL)METHYL BENZOATE; AZETIDINE DERIVATIVE; BETA LACTAM DERIVATIVE; BETA LACTAMASE INHIBITOR; CARBON; CARBONYL DERIVATIVE; N ACYLOXYMETHYLAZETIDIN 2 ONE; N HYDROXYMETHYLAZETIDIN 2 ONE; NITROGEN; OXYGEN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; KINETICS; PH;

ACIDS; AZETIDINES; CATALYSIS; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; IMINES; KINETICS; LACTAMS; MOLECULAR STRUCTURE;

EID: 2442475244     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0358123     Document Type: Article

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