A novel polymorphism in the 17β-hydroxysteroid dehydrogenase type 5 (aldo-keto reductase 1C3) gene is associated with lower serum testosterone levels in caucasian men

Pharmacogenomics Journal

Volumn 7, Issue 4, 2007, Pages 282-289

  Jakobsson, J ^a   Palonek, E ^a   Lorentzon, M ^b   Ohlsson, C ^b   Rane, A ^a   Ekstrom L ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; DNA; GLUTAMIC ACID; GLYCINE; GUANOSINE; TESTOSTERONE 17BETA DEHYDROGENASE; TESTOSTERONE 17BETA DEHYDROGENASE 5; UNCLASSIFIED DRUG; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 17BETA HYDROXYSTEROID DEHYDROGENASE TYPE 5, HUMAN; 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5, HUMAN; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AKR1C3 PROTEIN, HUMAN; HYDROXYSTEROID DEHYDROGENASE; LUCIFERASE; TESTOSTERONE;

ADULT; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ASIAN; CAUCASIAN; CELL STRAIN HEPG2; CELL STRAIN LNCAP; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; ETHNIC DIFFERENCE; EXON; GENE CONSTRUCT; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MAJOR CLINICAL STUDY; MALE; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE; PROTEIN EXPRESSION; REPORTER GENE; TESTOSTERONE BLOOD LEVEL; BLOOD; COMPARATIVE STUDY; EXPRESSED SEQUENCE TAG; GENETIC TRANSFECTION; GENETICS; INTRON; METABOLISM; NUCLEIC ACID DATABASE; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR CELL LINE; WESTERN BLOTTING;

17-HYDROXYSTEROID DEHYDROGENASES; 3-HYDROXYSTEROID DEHYDROGENASES; ASIAN CONTINENTAL ANCESTRY GROUP; BLOTTING, WESTERN; CELL LINE, TUMOR; DATABASES, NUCLEIC ACID; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; EXPRESSED SEQUENCE TAGS; GENE FREQUENCY; GENES, REPORTER; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; INTRONS; LUCIFERASES; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; TESTOSTERONE; TRANSFECTION;

EID: 34547634421     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500419     Document Type: Article

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