Low yield of polymorphisms from EST blast searching: Analysis of genes related to oxidative stress and verification of the P197L polymorphism in GPX1

Human Mutation

Volumn 13, Issue 4, 1999, Pages 294-300

  Forsberg, Lena ^a   De Faire, Ulf ^a   Morgenstern, Ralf ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

EST; PCR SSCP; Polymorphisms

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; SUPEROXIDE DISMUTASE;

AMINO ACID SUBSTITUTION; ARTICLE; DATA BASE; DNA POLYMORPHISM; DNA SEQUENCE; EXPRESSED SEQUENCE TAG; GENETIC ANALYSIS; HUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

DATABASES, FACTUAL; DNA PRIMERS; EXPRESSED SEQUENCE TAGS; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HUMANS; MICROSOMES; MODELS, GENETIC; MUTATION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA; SILVER STAINING; SUPEROXIDE DISMUTASE;

EID: 0033022968     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1004(1999)13:4<294::AID-HUMU6>3.0.CO;2-5     Document Type: Article

References (16)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman. 1997. Gapped BLAST and PSI-BLAST a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402.
2. Chu FF, Doroshow JH, Esworthy RS. 1993. Expression, characterization, and tissue distribution of a new cellular seleniumdependent glutathione peroxidase, GSHPx-GI. J Biol Chem 268:2571-2576.
3. Fridovich I. 1985. Superoxide dismutases: regularities and irregularities. Harvey Lect 79:51-75.
4. Gey K. 1993. Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease. Br Med Bull 49:679-699.
5. Halliwell B, Gutteridge JMC. 1989. Free radicals in biology and medicine. Oxford: Clarendon Press
6. Maniatis T, Fritsch EF, Sambrook J. 1989. Molecular cloning. A laboratory manual. Cold Spring Harbor: NY:Cold Spring Harbor Laboratory Press.
7. Marklund S. 1990. Expression of extracellular superoxide dismutase by human cell lines. Biochem J 299:213-219.
8. Masters C, Pegg M, Crane D. 1986. On the multiplicity of the enzyme catalase in mammalian liver. Mol Cell Biochem 70:113-120.
9. Michiels C, Raes M, Toussaint O, Remacle J. 1993. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radical Biol Med 17:235-248.
10. Mosialou E, Piemonte F, Andersson C, Vos R, Van Bladeren PJ, Morgenstern R. 1995. Microsomal glutathione transferaselipid-derived substrates and lipid dependence. Arch Biochem Biophys 320:210-216.
11. Ogata M. 1991. Acatalasemia. Hum Genet 86:331-340.
12. Omenn G. 1996. Micronutrients (vitamins and minerals) as cancer-preventive agents. IARC Sci Publ 139:33-45.
13. Takahashi K, Avissar N, Whitin J, Cohen H. 1987. Purification and characterization of human plasma glutathione peroxidase: a selenoglycoprotein distinct from the known cellular enzyme. Arch Biochem Biophys 256:677-686.
14. Ursini F, Maiorino M, Gregolin C. 1985. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochim. Biophys. Acta 839:62-70.
15. Ursini F, Maiorino M, Gregolin C. 1986. Phospholipid hydroperoxide glutathione peroxidase. Int J Tissue React 8:99-103.
16. Vidal-Puig A, Moller DE. 1994. Comparative sensitivity of alternative single-strand conformation polymorphism (SSCP) methods. Biotechniques 17:490-496.