Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: A common mechanism of disruption leads to divergent phenotypes

Development Growth and Differentiation

Volumn 49, Issue 6, 2007, Pages 533-541

  Naruse, Takuji ^a   Takahara, Masatoshi ^a   Takagi, Michiaki ^a   Oberg, Kerby C ^b   Ogino, Toshihiko ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Abnormal digital ray induction; Central deficiency; Central polydactyly; Cleft hand (foot); Syndactyly

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; BUSULFAN; FIBROBLAST GROWTH FACTOR 8; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CELL DEATH; CLEFT FOOT; CLEFT HAND; CONGENITAL BONE DISEASE; CONTROLLED STUDY; ECTODERM; EMBRYO; FEMALE; IN SITU HYBRIDIZATION; MESODERM; NICK END LABELING; NONHUMAN; POLYDACTYLY; RAT; STAINING; SYNDACTYLY;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BUSULFAN; DISEASE MODELS, ANIMAL; LIMB DEFORMITIES, CONGENITAL; POLYDACTYLY; RATS; SYNDACTYLY;

ERINACEIDAE; RATTUS;

EID: 34547450619     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2007.00949.x     Document Type: Article

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