Bronchoalveolar lavage quality influences the T4/T8 ratio in sarcoidosis

Respiratory Medicine

Volumn 101, Issue 9, 2007, Pages 2025-2030

  Reichenberger, Frank ^a   Kleiber, Brigitte ^a   Baschiera, Betty ^a   Bubendorf, Lukas ^a   Brutsche, Martin ^a   Dalquen, Peter ^a   Tamm, Michael ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

BAL; Lavage quality; Sarcoidosis; T4 T8 ratio

Indexed keywords

SODIUM CHLORIDE;

ARTICLE; BRONCHUS MUCUS; CD4 CD8 RATIO; CILIATED EPITHELIUM; CONTROLLED STUDY; FEMALE; HUMAN; LEUKOCYTE DIFFERENTIAL COUNT; LUNG LAVAGE; LUNG SARCOIDOSIS; LYMPHOCYTE COUNT; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; SQUAMOUS CELL;

BRONCHOALVEOLAR LAVAGE; BRONCHOALVEOLAR LAVAGE FLUID; CD4-CD8 RATIO; CELL COUNT; CILIA; FEMALE; HUMANS; LYMPHOCYTE COUNT; MALE; MUCUS; PROSPECTIVE STUDIES; SARCOIDOSIS, PULMONARY; SODIUM CHLORIDE; SPECIMEN HANDLING; T-LYMPHOCYTE SUBSETS;

EID: 34547434296     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2006.11.027     Document Type: Article

References (35)

1. Hunninghake G.W., Costabel U., Ando M., Baughman R., Cordier J.F., du Bois R., et al. ATS/ERS/ WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/ World Association of Sarcoidosis and other granulomatous disorders. Sarcoidosis Vasc Diffuse Lung Dis 16 (1999) 149-173
2. Müller-Quernheim J. Sarcoidosis: immunopathogenetic concepts and their clinical application. Eur Respir J 12 (1998) 716-738
3. Newmann L.S., Rose C.S., and Maier L.A. Medical progress: sarcoidosis. New Engl J Med 336 (1997) 1224-1234
4. Tessier V., Chadelat K., Baculard A., Houssetr B., and Clement A. BAL in children. A controlled study of differential cytology and cytokine expression profiles by alveolar cells in pediatric sarcoidosis. Chest 2109 (1996) 1430-1438
5. Poulter LW, Rossi GA, Bjermer L, Costabel U, Israel-Biet D, Klech H, Pohl W, Velluti G. The value of bronchoalveolar lavage in the diagnosis and prognosis of sarcoidosis. In: Klech H, Hutter C, editors. Clinical guidelines and indications for broncho-alveolar lavage (BAL): report of the European Society of Pneumology Task Group on BAL. Eur Respir J 1990; 3: 937-74.
6. Wahlström J Berlin M., Sköle C.M., Wigzell H., Eklund A., and Grunewald J. Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis. Thorax 54 (1999) 339-346
7. Costabel U., Zaiss A.W., and Guzman J. Sensitivity and specificity of BAL findings in sarcoidosis. Sarcoidosis 2 (1992) 211-214
8. Winterbauer R.H., Lammer J., Selland M., Wu R., Corley D., and Springmeyer S.C. Bronchoalveolar lavage cell populations in the diagnosis of sarcoidosis. Chest 104 (1993) 352-361
9. Kantrow S.P., Meyer KC Kidd P., and Ranghu G. The CD4/CD8 ratio in BAL fluid is highly variable in sarcoidosis. Eur Respir J 10 (1997) 2716-2721
10. Helmers R.A., Dayton C.S., Floerchinger C., and Hunninghake G.W. Bronchoalveolar lavage in interstitial lung disease: effect of volume of fluid infused. J Appl Physiol 67 (1989) 1443-1446
11. Costabel U. CD4/CD8 ratios in bronchoalveolar lavage fluid: of value for diagnosing sarcoidosis?. Eur Respir J 10 (1997) 1699-2700
12. Leonard C., Tormey V.J., O'Keane C., and Burke C.M. Bronchoscopic diagnosis of sarcoidosis. Eur Respir J 10 (1997) 2722-2724
13. Nagai S., and Izumi T. Bronchoalveolar lavage. Still useful in diagnosing sarcoidosis?. Clin Chest Med 18 (1997) 787-797
14. Costabel U., Bross K.J., Guzman J., Nilles A., Puhle K.H., and Matthys H. Predictive value of bronchoalveolar T cell subsets for the course of pulmonary sarcoidosis. Ann NY Acad Sci 465 (1986) 126-418
15. Agostini C., Trentin L., Zambello R., Bulian P., Siviero F., Masciarelli M., et al. CD8 alveolitis in sarcoidosis: incidence, phenotype characteristics, and clinical features. Am J Med 95 (1993) 466-472
16. Wahlström J., Katchar K., Wigzell H., Olerup O., Eklund A., and Grunewald J. Analysis of intracellular cytrokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis. Am J Respir Crit Care Med 163 (2001) 115-121
17. Marruchella A., and Todini M. Reliability of bronchoalveolar lavage in the routine clinical assessment of patients with sarcoidosis. A retrospective analysis. Panminerva Med 44 (2002) 257-260
18. Keogh B.A., Hunnunghake G.W., Line B.R., and Crystral R.G. The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function. Am Rev Respir Dis 128 (1983) 256-265
19. Pabst R., and Tschernig T. Lymphocyte dynamics: caution in interpreting BAL numbers. Thorax 52 (1997) 1078-1080
20. Kunitake R., Kunwano K., Miyazaki H., Hagimoto N., Nomoto Y., and Hara N. Apoptosis in the course of granulomatous inflammation in pulmonary sarcoidosis. Eur Respir J 13 (1999) 1329-1337
21. Ohtsuka M., Yoshizawa Y., Naitou T., Yano H., Sato T., and Hasegawa S. The motility of lung lymphocytes in hypersensitivity pneumonitis and sarcoidosis. Am J Respir Crit Care Med 149 (1994) 455-459
22. Garcia J.G.N., Wolven R.G., Garcia P.L., and Keogh B.A. Assessment of interlobar variation of bronchoalveolar lavage cellular differentials in intersitial lung disease. Am Rev Respir Dis 133 (1986) 444-449
23. Klech H., and Pohl W. Technical recommendations and guidelines for bronchoalveolar lavage (BAL): report of the European Society for Pneumology Task Group of BAL. Eur Respir J 3 (1990) 937-974
24. Mordelet-Dambrine M., Arnoux A., Stanislas-Leguern G., Sandron D., Chrétien J., and Huchon G. Processing of lung lavage fluid causes variability of bronchoalveolar cell count. Am Rev Respir Dis 130 (1984) 305-306
25. Chamberlain D.W., Braude A.C., and Rebuck A.S. A critical evaluation of bronchoalveolar lavage. Criteria for identifying unsatisfactory specimens. Acta Cytol 31 (1987) 599-605
26. Stoller J.K., Rankin J.A., and Reynolds H.Y. The impact of bronchoalveolar lavage cell analysis on clinicians' diagnostic reasoning about interstitial lung disease. Chest 92 (1987) 839-843
27. Laviolette M., La Forge J., Tennia S., and Boulet L.P. Prognostic value of bronchoalveolar lymphocyte count in recently diagnosed pulmonary sarcoidosis. Chest 100 (1991) 380-384
28. Hunninghake G.W., Gilber S., Pueringer R., Dayton C., Floerchinger C., Helmers R., et al. Outcome of the treatment for sarcoidosis. Am J Respir Crit Care Med 149 (1998) 893-898
29. Davis G.S. Bronchoalveolar lavage and the technological dilemma. Am Rev Respir Dis 133 (1986) 181-183
30. Lam S., Leriche J.C., Kijek K., and Phillips D. Effect of bronchoalveolar lavage volume on cellular and protein recovery. Chest 88 (1985) 856-859
31. De Brauwer E.I., Drent M., Mulder P.G., Bruggemaqn C.A., Wagenaar S.S., and Jacobs J.A. Differential cell analysis of cytocentrifuged bronchoalveolar fluid samples affected by the area counted. Anal Quant Cytol Histol 22 (2000) 143-149
32. Thomas M., von Eiff M., Brandt B., Heinecke A., and van de Loo J. Immunophenotyping of lymphocytes in bronchoalveolar lavage fluid. Chest 108 (1995) 464-469
33. Barry S.M., and Janossy G. Optimal gating strategies for determining bronchoalveolar lavage CD4/CD8 lymphocyte ration by flow cytometry. J Immunol Meth 285 (2004) 15-23
34. D′Ippolito R., Foresi A., Chetta A., Casalini A., Castagnaro A., leone C., et al. Induced sputum in patietns with newly diagnosed sarcoidosis. Chest 115 (1999) 1611-1615
35. Moodley Y.P., Dorasamy T., Venketasamy S., Naicker V., and Lalloo U.G. Correlation of CD4:CD8 ratio and tumour necrosis factor (TNF)alpha levels in induced sputum with bronchoalveolar lavage fluid in pulmonary sarcoidosis. Thorax 55 (2000) 696-699