Lymphocyte dynamics: Caution in interpreting BAL numbers

Thorax

Volumn 52, Issue 12, 1997, Pages 1078-1080

  Pabst, Reinhard ^a   Tschernig, Thomas ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Apoptosis; Bronchoalveolar lavage; Lymphocyte dynamics; Lymphocytes; Origin; Proliferation

Indexed keywords

CHEMOKINE; CYTOKINE;

ALLERGIC REACTION; APOPTOSIS; CELL DIVISION; DYNAMICS; ETIOLOGY; LUNG LAVAGE; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0030722438     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.52.12.1078     Document Type: Short Survey

References (12)

1. Klech H, Pohl W, eds. Technical recommendations and guidelines for bronchoalveolar lavage (BAL). Eur Respir J 1989;2:561-85.
2. Semenzato G. Immunology of interstitial lung diseases: cellular events taking place in the lung of sarcoidosis, hypersensitivity pneumonitis and HIV infection. Eur Respir J 1991;4:94-102.
3. Corrigan CJ, Kay AB. The lymphocyte in asthma. In: Busse WW, Holgate SF, eds. Asthma and rhinitis. Boston: Blackwell Science, 1995: 450-64.
4. Pabst R, Tschernig T. What is known about the life span and fate of lymphocytes in the bronchoalveolar space? In: Husband AJ, ed. Mucosal solutions - advances in mucosal immunology. Sydney University, 1997 (in press).
5. Pabst R, Tschernig T. Lymphocytes in the lung: an often neglected cell. Numbers, characterization and compartmentalization. Anat Embryol 1995;192:293-9.
6. Spain BA, Soliman DM, Sidner RA, Twigg HL. Enhanced proliferation and IL-2 secretion by lung lymphocytes from HIV-infected subjects. Am J Physiol 1995;269:L498-506.
7. Chilosi M, Menestrina F, Capelli P, Montagna L, Lestani M, Pizzolo G, et al. Immunohistochemical analysis of sarcoid granulomas. Evaluation of Ki67 + and interleukin-1 + cells. Am J Pathol 1988;131:191-8.
8. Agostini C, Zambello R, Sancetta R, Cerutti A, Milani A, Tassinari C, et al. Expression of tumor necrosis factor-receptor superfamily members by lung T lymphocytes in interstitial lung disease. Am J Respir Crit Care Med 1996; 153:1359-67.
9. Buechner-Maxwell VA, Milik AM, Sonstein J, Seitzman GD, Beals TF, Curtis JL. Apoptosis contributes to lung lymphocyte elimination in the murine response to intratracheal sheep erythrocytes. Am J Respir Crit Care Med 1995;151:A234.
10. Kaan PM, Hegele RG, Hayashi S, Hogg JC. Expression of bcl-2 and Epstein-Barr virus LMP-1 in lymphocytic interstitial pneumonia. Thorax 1997;52:12-6.
11. Pabst R, Binns RM. Lymphocytes migrate from the bronchoalveolar space to regional bronchial lymph nodes. Am J Respir Crit Care Med 1995;151:495-9.
12. Sandström T, Bjermer L, Rylander R. Lipopolysaccharide (LPS) inhalation in healthy subjects increases neutrophils, lymphocytes and fibronectin levels in bronchoalveolar lavage fluid. Eur Respir J 1992;5:992-6.