-
1
-
-
0024328078
-
Lovastatin
-
Alberts, A. W., MacDonald, J. S., Till, A. E., and Tobert, J. A. (1989). Lovastatin. Cardiovasc. Drug Rev. 7, 89-109.
-
(1989)
Cardiovasc. Drug Rev.
, vol.7
, pp. 89-109
-
-
Alberts, A.W.1
MacDonald, J.S.2
Till, A.E.3
Tobert, J.A.4
-
2
-
-
0011796074
-
Relationship between breeding performance and testicular/epididymal functioning in male Sprague-Dawley rats exposed to nitrobenzene
-
Blazak, W. F., Rushbrook, C. J., Ernst, T. L., Stewart, B. E., Spak, D., DiBiasio-Erwin, D., and Black, V. (1985). Relationship between breeding performance and testicular/epididymal functioning in male Sprague-Dawley rats exposed to nitrobenzene. Toxicologist 5, 121.
-
(1985)
Toxicologist
, vol.5
, pp. 121
-
-
Blazak, W.F.1
Rushbrook, C.J.2
Ernst, T.L.3
Stewart, B.E.4
Spak, D.5
DiBiasio-Erwin, D.6
Black, V.7
-
3
-
-
0002326581
-
Application of testicular sperm head counts in the assessment of male reproductive toxicity
-
(R. E. Chapin and J. J. Heindel, Eds.), Academic Press, San Diego
-
Blazak, W. F., Treinen, K. A., and Juniewicz, P. E. (1993). Application of testicular sperm head counts in the assessment of male reproductive toxicity. In Methods in Toxicology: Male Reproductive Toxicology (R. E. Chapin and J. J. Heindel, Eds.), Vol. 3, Part A, pp. 86-94. Academic Press, San Diego.
-
(1993)
Methods in Toxicology: Male Reproductive Toxicology
, vol.3
, Issue.PART A
, pp. 86-94
-
-
Blazak, W.F.1
Treinen, K.A.2
Juniewicz, P.E.3
-
4
-
-
0027383840
-
Long-term endocrine function in hypercholesterolemic patients treated with pravastatin, a new 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor
-
Dobs, A. S., Sarma, P. S., and Schteingart, D. (1993). Long-term endocrine function in hypercholesterolemic patients treated with pravastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Metabolism 42, 1146-1152.
-
(1993)
Metabolism
, vol.42
, pp. 1146-1152
-
-
Dobs, A.S.1
Sarma, P.S.2
Schteingart, D.3
-
5
-
-
0028642271
-
Developmental toxicity of the HMG-CoA reductase inhibitor, atorvastatin, in rats and rabbits
-
Dostal, L. A., Schardein, J. L., and Anderson, J. A. (1994). Developmental toxicity of the HMG-CoA reductase inhibitor, atorvastatin, in rats and rabbits. Teratology 50, 387-394.
-
(1994)
Teratology
, vol.50
, pp. 387-394
-
-
Dostal, L.A.1
Schardein, J.L.2
Anderson, J.A.3
-
6
-
-
0011794768
-
Semen analysis and sperm counts in beagle dogs treated with the HMG-CoA reductase inhibitor, atorvastatin
-
Dostal, L. A., Faber, C. K., Rothwell, C. E., and Anderson, J. A. (1995). Semen analysis and sperm counts in beagle dogs treated with the HMG-CoA reductase inhibitor, atorvastatin. Toxicologist 15, 248.
-
(1995)
Toxicologist
, vol.15
, pp. 248
-
-
Dostal, L.A.1
Faber, C.K.2
Rothwell, C.E.3
Anderson, J.A.4
-
7
-
-
0018645473
-
Effects of ML-236B on cholesterol metabolism in mice and rats: Lack of hypocholesterolemic activity in normal animals
-
Endo, A., Tsujita, Y., Kuroda, M., and Tanzawa, K. (1979). Effects of ML-236B on cholesterol metabolism in mice and rats: Lack of hypocholesterolemic activity in normal animals. Biochim. Biophys. Acta 575, 266-276.
-
(1979)
Biochim. Biophys. Acta
, vol.575
, pp. 266-276
-
-
Endo, A.1
Tsujita, Y.2
Kuroda, M.3
Tanzawa, K.4
-
8
-
-
0023238831
-
Testicular function in type II hyperlipoproteinemic patients treated with lovastatin (mevinolin) or neomycin
-
Farnsworth, W. H., Hoeg, J. M., Maher, M., Brittain, E. H., Sherins, R. J., and Brewer, H. B., Jr. (1987). Testicular function in Type II hyperlipoproteinemic patients treated with lovastatin (mevinolin) or neomycin. J. Clin. Endocrinol. Metab. 65, 546-550.
-
(1987)
J. Clin. Endocrinol. Metab.
, vol.65
, pp. 546-550
-
-
Farnsworth, W.H.1
Hoeg, J.M.2
Maher, M.3
Brittain, E.H.4
Sherins, R.J.5
Brewer H.B., Jr.6
-
11
-
-
0024820011
-
Lovastatin and other HMG-CoA reductase inhibitors
-
Frishman, W. H., Zimetbaum, P., and Nadelmann, J. (1989). Lovastatin and other HMG-CoA reductase inhibitors. J. Clin. Pharmacol. 29, 975-982.
-
(1989)
J. Clin. Pharmacol.
, vol.29
, pp. 975-982
-
-
Frishman, W.H.1
Zimetbaum, P.2
Nadelmann, J.3
-
12
-
-
0024972452
-
Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme a reductase inhibitors
-
Gerson, R. J., MacDonald, J. S., Alberts, A. W., Kornbrust, D. J., Majka, J. A., Stubbs, R. J., and Bokelman, D. L. (1989). Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors. Am. J. Med. 87(Suppl. 4A), 28S-38S.
-
(1989)
Am. J. Med.
, vol.87
, Issue.SUPPL. 4A
-
-
Gerson, R.J.1
MacDonald, J.S.2
Alberts, A.W.3
Kornbrust, D.J.4
Majka, J.A.5
Stubbs, R.J.6
Bokelman, D.L.7
-
13
-
-
0004061014
-
-
Dekker, New York
-
Gibaldi, M., and Perrier, D. (1982). Pharmacokinetics, 2nd ed., Dekker, New York.
-
(1982)
Pharmacokinetics, 2nd Ed.
-
-
Gibaldi, M.1
Perrier, D.2
-
14
-
-
0000230038
-
International conference on harmonisation: Guideline on detection of toxicity to reproduction for medicinal products
-
22
-
ICH (1994). International conference on harmonisation: Guideline on detection of toxicity to reproduction for medicinal products. Fed. Reg. 59(183), 22, 48746-48752.
-
(1994)
Fed. Reg.
, vol.59
, Issue.183
, pp. 48746-48752
-
-
-
15
-
-
0029113047
-
Lipid-lowering activity of atorvastatin and lovastatin in rodent species: Triglyceride-lowering in rats correlates with efficacy in LDL animal models
-
Krause, B. R., and Newton, R. S. (1995). Lipid-lowering activity of atorvastatin and lovastatin in rodent species: Triglyceride-lowering in rats correlates with efficacy in LDL animal models. Atherosclerosis 117, 237-244.
-
(1995)
Atherosclerosis
, vol.117
, pp. 237-244
-
-
Krause, B.R.1
Newton, R.S.2
-
16
-
-
0023733253
-
Preclinical evaluation of lovastatin
-
MacDonald, J. S., Gerson, R. J., Kornbrust, D. J., Kloss, M. W., Prahalada, S., Berry, P. H., Alberts, A. W., and Bokelman, D. L. (1988). Preclinical evaluation of lovastatin. Am. J. Cardiol. 62, 16J-27J.
-
(1988)
Am. J. Cardiol.
, vol.62
-
-
MacDonald, J.S.1
Gerson, R.J.2
Kornbrust, D.J.3
Kloss, M.W.4
Prahalada, S.5
Berry, P.H.6
Alberts, A.W.7
Bokelman, D.L.8
-
17
-
-
84987493079
-
Quantitative correlation between testicular stem cell survival, sperm production and fertilization in mouse after treatment with different cytotoxic agents
-
Meistrich, M. L. (1982). Quantitative correlation between testicular stem cell survival, sperm production and fertilization in mouse after treatment with different cytotoxic agents. J. Androl. 3, 58-68.
-
(1982)
J. Androl.
, vol.3
, pp. 58-68
-
-
Meistrich, M.L.1
-
18
-
-
0021091138
-
Mevalonate supplementation in pregnant rats suppresses the teratogenicity of mevinolinic acid, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
-
Minsker, D. H., MacDonald, J. S., Robertson, R. T., and Bokelman, D. L. (1983). Mevalonate supplementation in pregnant rats suppresses the teratogenicity of mevinolinic acid, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Teratology 28, 449-456.
-
(1983)
Teratology
, vol.28
, pp. 449-456
-
-
Minsker, D.H.1
MacDonald, J.S.2
Robertson, R.T.3
Bokelman, D.L.4
-
19
-
-
0023732838
-
Association of sperm, vaginal cytology, and reproductive organ weight data with results of continuous breeding reproduction studies in Swiss (CD-1) mice
-
Morrissey, R. E., Lamb, J. C., Schwetz, B. A., Teague, J. L., and Morris, R. W. (1988). Association of sperm, vaginal cytology, and reproductive organ weight data with results of continuous breeding reproduction studies in Swiss (CD-1) mice. Fundam. Appl. Toxicol. 11, 359-371.
-
(1988)
Fundam. Appl. Toxicol.
, vol.11
, pp. 359-371
-
-
Morrissey, R.E.1
Lamb, J.C.2
Schwetz, B.A.3
Teague, J.L.4
Morris, R.W.5
-
20
-
-
0029043903
-
Reductions of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor
-
Nawrocki, J. W., Weiss, S. R., Davidson, M. H., Sprecher, D. L., Schwartz, S. L., Lupien, P.-J., Jones, P. H., Haber, H. E., and Black, D. M. (1995). Reductions of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler. Thromb. Vasc. Biol. 15, 678-682.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 678-682
-
-
Nawrocki, J.W.1
Weiss, S.R.2
Davidson, M.H.3
Sprecher, D.L.4
Schwartz, S.L.5
Lupien, P.-J.6
Jones, P.H.7
Haber, H.E.8
Black, D.M.9
-
23
-
-
0026604874
-
Short-term effects of treatment with simvastatin on testicular function in patients with heterozygous familial hypercholesterolaemia
-
Purvis, K., Tollefsrud, A., Rui, H., Haug, E., Norseth, J., Viksmoen, L., Ose, L., and Lund, H. (1992). Short-term effects of treatment with simvastatin on testicular function in patients with heterozygous familial hypercholesterolaemia. Eur. J. Clin. Pharmacol. 42, 61-64.
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.42
, pp. 61-64
-
-
Purvis, K.1
Tollefsrud, A.2
Rui, H.3
Haug, E.4
Norseth, J.5
Viksmoen, L.6
Ose, L.7
Lund, H.8
-
24
-
-
0021178831
-
Suppression of spermatogenesis by testosterone in adult male rats: Effect on fertility, pregnancy outcome and progeny
-
Robaire, B., Smith, S., and Hales, B. F. (1984). Suppression of spermatogenesis by testosterone in adult male rats: Effect on fertility, pregnancy outcome and progeny. Biol. Reprod. 31, 221-230.
-
(1984)
Biol. Reprod.
, vol.31
, pp. 221-230
-
-
Robaire, B.1
Smith, S.2
Hales, B.F.3
-
25
-
-
0023552146
-
Reproduction study of pravastatin sodium administered prior to and in the early stages of pregnancy in rats
-
Tanase, H., and Hirose, K. (1987). Reproduction study of pravastatin sodium administered prior to and in the early stages of pregnancy in rats. Jpn. Pharmacol. Ther. 15, 4975-4982.
-
(1987)
Jpn. Pharmacol. Ther.
, vol.15
, pp. 4975-4982
-
-
Tanase, H.1
Hirose, K.2
-
26
-
-
77957176178
-
Adverse male reproductive effects following subchronic exposure of rats to sodium dichloroacetate
-
Toth, G. P., Kelty, K. C., George, E. L., Read, E. J., and Smith, M. K. (1992). Adverse male reproductive effects following subchronic exposure of rats to sodium dichloroacetate. Fundam. Appl. Toxicol. 19, 57-63.
-
(1992)
Fundam. Appl. Toxicol.
, vol.19
, pp. 57-63
-
-
Toth, G.P.1
Kelty, K.C.2
George, E.L.3
Read, E.J.4
Smith, M.K.5
-
27
-
-
0022039941
-
Testing the statistical certainty of a response to increasing doses of a drug
-
Tukey, J. W., Ciminera, J. L., and Heyse, J. F. (1985). Testing the statistical certainty of a response to increasing doses of a drug. Biometrics 42, 295-301.
-
(1985)
Biometrics
, vol.42
, pp. 295-301
-
-
Tukey, J.W.1
Ciminera, J.L.2
Heyse, J.F.3
-
28
-
-
0022485201
-
CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase: Tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species
-
Tsujita, Y., Kuroda, M., Shimada, Y., Tanzawa, K., Arai, M., Kaneko, I., Tanaka, M., Masuda, H., Tarumi, C., Watanabe, Y., and Fujii, S. (1986). CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: Tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species. Biochim. Biophys. Acta 887, 50-60.
-
(1986)
Biochim. Biophys. Acta
, vol.887
, pp. 50-60
-
-
Tsujita, Y.1
Kuroda, M.2
Shimada, Y.3
Tanzawa, K.4
Arai, M.5
Kaneko, I.6
Tanaka, M.7
Masuda, H.8
Tarumi, C.9
Watanabe, Y.10
Fujii, S.11
-
29
-
-
0025277703
-
Simvastatin (MK-0733): Oral fertility study in rats
-
Wise, L. D., Minsker, D. H., Robertson, R. T., Bokelman, D. L., Akutsu, S., and Fujii, T. (1990). Simvastatin (MK-0733): Oral fertility study in rats. Oyo Yakuri/Pharmacometrics 39, 127-141.
-
(1990)
Oyo Yakuri/Pharmacometrics
, vol.39
, pp. 127-141
-
-
Wise, L.D.1
Minsker, D.H.2
Robertson, R.T.3
Bokelman, D.L.4
Akutsu, S.5
Fujii, T.6
-
30
-
-
0011796077
-
Chemical induction of sperm abnormalities in mice
-
Wyrobek, A. J., and Bruce, W. R. (1975). Chemical induction of sperm abnormalities in mice. Proc. Natl. Acad. Sci. USA 72, 4423-4429.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 4423-4429
-
-
Wyrobek, A.J.1
Bruce, W.R.2
|