Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into human chondrocytes

Arthritis Research and Therapy

Volumn 8, Issue 4, 2006, Pages

  Kim, Hyun Ah ^a   Kim, Dae Won ^b   Park, Jinseu ^b   Choi, Soo Young ^b  

^a Hallym University Sacred Heart Hospital   (South Korea)

^b Hallym University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; MESSENGER RNA; NITRIC OXIDE; SUPEROXIDE DISMUTASE; TRANSACTIVATOR PROTEIN;

BIOSYNTHESIS; CARTILAGE CELL; CELL CULTURE; DRUG EFFECTS; FEASIBILITY STUDY; GENE FUSION; GENETIC TRANSDUCTION; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; OSTEOARTHRITIS; PATHOLOGY; PROCEDURES; PROTEIN TERTIARY STRUCTURE; UPREGULATION;

CELLS, CULTURED; CHONDROCYTES; FEASIBILITY STUDIES; GENE FUSION; GENE PRODUCTS, TAT; HUMANS; IN VITRO TECHNIQUES; INTERLEUKIN-1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TRANSDUCTION, GENETIC; UP-REGULATION;

EID: 34547176266     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar1972     Document Type: Article

References (30)

1. Goldring MB: The role of the chondrocyte in osteoarthritis. Arthritis Rheum 2000, 43:1916-1926.
2. Tiku ML, Shah R, Allison GT: Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis. J Biol Chem 2000, 275:20069-20076.
3. Jin LH, Bahn JH, Eum WS, Kwon HY, Jang SH, Han KH, Kang TC, Won MH, Kang JH, Cho SW, et al.: Transduction of human catalase mediated by an HIV-1 TAT protein basic domain and arginine-rich peptides into mammalian cells. Free Radic Biol Med 2001, 31:1509-1519.
4. Mates M: Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 2000, 153 83-104.
5. Halliwell B, Gutteridge JMC: Role of free radicals and catalytic metal ions in human disease: An overview. Methods Enzymol 1990, 186:1-85.
6. Venkatesan N, Barre L, Benani A, Netter P, Magdalou J, Fournel- Gigleux S, Ouzzine M: Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: A strategy to promote cartilage repair. Proc Natl Acad Sci USA 2004, 101:18087-18092.
7. Pelletier JP, Caron JP, Evans C, Robbins PD, Georgescu HI, Jovanovic D, Fernandes JC, Martel-Pelletier J: In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum 1997, 40:1012-1019.
8. Arai Y, Kubo T, Kobayashi K, Takeshita K, Takahashi K, Ikeda T, Imanishi J, Takigawa M, Hirasawa Y: Adenovirus vector-mediated gene transduction to chondrocytes: In vitro evaluation of therapeutic efficacy of transforming growth factor-beta 1 and heat shock protein 70 gene transduction. J Rheumatol 1997, 24:1787-1795.
9. Ma M, Nath A: Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. J Virol 1997, 71:2495-2499.
10. Vives E, Brodin P, Lebleu B: A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 1997, 272:16010-16017.
11. Elliott G, O'Hare P: Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 1997, 88 223-233.
12. Derossi D, Joliot AH, Chassaing G, Prochiantz A: The third helix of the Antennapedia homeodomain translocates through biological membranes J Biol Chem 1994, 269:10444-10450.
13. Asoh S, Ohsawa I, Mori T, Katsura K, Hiraide T, Katayama Y, Kimura M, Ozaki D, Yamagata K, Ohta S: Protection against ischemic brain injury by protein therapeutics. Proc Natl Acad Sci USA 2002, 99 17107-17112.
14. Kang JH, Choi BJ, Kim SM: Expression and characterization of recombinant human Cu, Zn-superoxide dismutase in Escherichia coli. J Biochem Mol Biol 1997, 30:60-65.
15. Kwon HY, Eum WS, Jang HW, Kang JH, Ryu J, Lee BR, Jin LH, Park J, Choi SY: Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells. FEBS Lett 2000, 485:163-167.
16. Eum WS, Choung IS, Kim AY, Lee YJ, Kang JH, Park J, Lee KS, Kwon HY, Choi SY: Transduction efficacy of Tat-Cu, Zn-superoxide dismutase is enhanced by copper ion recovery of the fusion protein. Mol Cells 2002, 13:334-340.
17. Park J, Ryu J, Kim KA, Lee HJ, Bahn JH, Han K, Choi EY, Lee KS, Kwon HY, Choi SY: Mutational analysis of a human immunodeficiency virus type 1 Tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J Gen Virol 2002, 83 1173-1181.
18. Kim HA, Lee KB, Bae SC: The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death. Arthritis Res Ther 2005, 7:R526-535.
19. McCord JM, Fridovich I: Superoxide dismutase. J Biol Chem 1969, 244:6049-6055.
20. Mendes AF, Caramona MM, Carvalho AP, Lopes MC: Differential roles of hydrogen peroxide and superoxide in mediating IL-1- induced NF-kappa B activation and iNOS expression in bovine articular chondrocytes. J Cell Biochem 2003, 88:783-793.
21. Kabouridis PS, Hasan M, Newson J, Gilroy DW, Lawrence T: Inhibition of NF-kappa B activity by a membrane-transducing mutant of I kappa B alpha. J Immunol 2002, 169:2587-2593.
22. Ozaki D, Sudo K, Asoh S, Yamagata K, Ito H, Ohta S: Transduction of anti-apoptotic proteins into chondrocytes in cartilage slice culture. Biochem Biophys Res Commun 2004, 313:522-527.
23. Klein D, Ribeiro MM, Mendoza V, Jayaraman S, Kenyon NS, Pileggi A, Molano RD, Inverardi L, Ricordi C, Pastori RL: Delivery of Bcl- XL or its BH4 domain by protein transduction inhibits apoptosis in human islets. Biochem Biophys Res Commun 2004, 323:473-478.
24. Lee H, Ryu J, Kim KA, Lee KS, Lee JY, Park JB, Park J, Choi SY: Transduction of yeast cytosine deaminase mediated by HIV-1 Tat basic domain into tumor cells induces chemosensitivity to 5-fluorocytosine. Exp Mol Med 2004, 36:43-51.
25. Blackwell NM, Sembi P, Newson JS, Lawrence T, Gilroy DW, Kabouridis PS: Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor. Arthritis Rheum 2004, 50 2675-2684.
26. Eum WS, Choung IS, Li MZ, Kang JH, Kim DW, Park J, Kwon HY, Choi SY: HIV-1 Tat-mediated protein transduction of Cu, Znsuperoxide dismutase into pancreatic beta cells in vitro and in vivo. Free Radic Biol Med 2004, 37:339-349.
27. Wang W, El-Deiry WS: Targeting p53 by PTD-mediated transduction. Trends Biotechnol 2004, 22:431-434.
28. Wadia JS, Stan RV, Dowdy SF: Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis Nat Med 2004, 10:310-315.
29. Hashida H, Miyamoto M, Cho Y, Hida Y, Kato K, Kurokawa T, Okushiba S, Kondo S, Dosaka-Akita H, Katoh H: Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool. Br J Cancer 2004, 90:1252-1258.
30. Regan E, Flannelly J, Bowler R, Tran K, Nicks M, Carbone BD, Glueck D, Heijnen H, Mason R, Crapo J: Extracellular superoxide dismutase and oxidant damage in osteoarthritis. Arthritis Rheum 2005, 52 3479-3491.