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For selected reviews on aldol and other related reactions using asymmetric organocatalysis, see: (a) List, B. Chem. Commun. 2006, 819.
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33845728625
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For a very interesting discussion on whether this kind of reaction should be called in water, on water, in the presence of water, or concentrated organic phases, see: a
-
For a very interesting discussion on whether this kind of reaction should be called "in water", "on water", "in the presence of water", or "concentrated organic phases", see: (a) Brogan, A. P.; Dickerson, T. J.; Janda, K. D. Angew. Chem., Int. Ed. 2006, 45, 8100.
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The above phrases in using water for the reaction are a matter of semantics. However, we prefer to use in an aqueous medium for our reactions.
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The above phrases in using water for the reaction are a matter of semantics. However, we prefer to use "in an aqueous medium" for our reactions.
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For some recent selected references on aldol reaction in water via asymmetric organocatalysis, see: a
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For some recent selected references on aldol reaction in water via asymmetric organocatalysis, see: (a) Guizzetti, S.; Benaglia, M.; Raimondi, L.; Celentano, G. Org. Un. 2007, 9, 1247.
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