Eosinophilia is induced in the colon of Th2-sensitized mice upon exposure to locally expressed antigen

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 293, Issue 1, 2007, Pages

  Zhu, Qing ^a,c   Thomson, Christopher W ^a   Zhang, Guofeng ^b   Stämpfli, Martin ^a   McDermott, Mark R ^a   Collins, Stephen M ^a   Gauldie, Jack ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Adenovirus; Eosinophil; Intrarectal; Mucosal

Indexed keywords

ADENOVIRUS VECTOR; ALUMINUM HYDROXIDE; ANTIGEN; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL DAMAGE; CELLULAR IMMUNITY; COLITIS; COLON MUCOSA; CONTROLLED STUDY; EOSINOPHILIA; EPITHELIUM CELL; FEMALE; GENETIC CODE; IMMUNE RESPONSE; LEUKOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; TH2 CELL;

ADENOVIRIDAE; ANIMALS; COLON; EOSINOPHILIA; FEMALE; GENETIC VECTORS; MICE; MICE, INBRED BALB C; OVALBUMIN; TH2 CELLS;

EID: 34547133294     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00341.2006     Document Type: Article

References (58)

1. Addison CL, Hitt M, Kunsken D, Graham FL. Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. J Gen Virol 78: 1653-1661, 1997.
2. Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F. Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation. Gastroenterology 128: 654-666, 2005.
3. Beyer K, Castro R, Birnbaum A, Benkov K, Pittman N, Sampson HA. Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile. J Allergy Clin Immunol 109: 707-713, 2002.
4. Braciak TA, Gallichan WS, Graham FL, Richards CD, Ramsay AJ, Rosenthal KL, Gauldie J. Recombinant adenovirus vectors expressing interleukin-5 and -6 specifically enhance mucosal immunoglobulin A responses in the lung. Immunology 101: 388-396, 2000.
5. Daneshjoo R, Talley NJ. Eosinophilic gastroenteritis. Curr Gastroenterol Rep 4: 366-372, 2002.
6. Desreumaux P, Bloget F, Seguy D, Capron M, Cortot A, Colombel JF, Janin A. Interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 in eosinophilic gastroenteritis. Gastroenterology 110: 768-774, 1996.
7. Dohi T, Fujihashi K, Kiyono H, Elson CO, McGhee JR. Mice deficient in Th1- and Th2-type cytokines develop distinct forms of hapten-induced colitis. Gastroenterology 119: 724-733, 2000.
8. Dohi T, Fujihashi K, Rennert PD, Iwatani K, Kiyono H, McGhee JR. Hapten-induced colitis is associated with colonic patch hypertrophy and T helper cell 2-type responses. J Exp Med 189: 1169-1180, 1999.
9. Dombrowicz D, Capron M. Eosinophils, allergy and parasites. Curr Opin Immunol 13: 716-720, 2001.
10. Forbes E, Murase T, Yang M, Matthaei KI, Lee JJ, Lee NA, Foster PS, Hogan SP. Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase. J Immunol 172: 5664-5675, 2004.
11. Foreman PK, Wainwright MJ, Alicke B, Kovesdi I, Wickham TJ, Smith JG, Meier-Davis S, Fix JA, Daddona P, Gardner P, Huang MT. Adenovirus-mediated transduction of intestinal cells in vivo. Hum Gene Ther 9: 1313-1321, 1998.
12. Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 183: 195-201, 1996.
13. Gallichan WS, Rosenthal KL. Effects of the estrous cycle on local humoral immune responses and protection of intranasally immunized female mice against herpes simplex virus type 2 infection in the genital tract. Virology 224: 487-497, 1996.
14. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 2: 449-456, 1996.
15. Gleich GJ, Adolphson CR. The eosinophilic leukocyte: structure and function. Adv Immunol 39: 177-253, 1986.
16. Gould HJ, Sutton BJ, Beavil AJ, Beavil RL, McCloskey N, Coker HA, Fear D, Smurthwaite L. The biology of IGE and the basis of allergic disease. Annu Rev Immunol 21: 579-628, 2003.
17. Hamada H, Hiroi T, Nishiyama Y, Takahashi H, Masunaga Y, Hachimura S, Kaminogawa S, Takahashi-Iwanaga H, Iwanaga T, Kiyono H, Yamamoto H, Ishikawa H. Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J Immunol 168: 57-64, 2002.
18. Haque S, Eisen RN, West AB. The morphologic features of diversion colitis: studies of a pediatric population with no other disease of the intestinal mucosa. Hum Pathol 24: 211-219, 1993.
19. Hata K, Andoh A, Sato H, Araki Y, Tanaka M, Tsujikawa T, Fujiyama Y, Bamba T. Sequential changes in luminal microflora and mucosal cytokine expression during developing of colitis in HLA-B27/ beta2-microglobulin transgenic rats. Scand J Gastroenterol 36: 1185-1192, 2001.
20. Higgins LM, Frankel G, Connerton I, Goncalves NS, Dougan G, MacDonald TT. Role of bacterial intimin in colonic hyperplasia and inflammation. Science 285: 588-591, 1999.
21. Hill SM, Milla PJ. Colitis caused by food allergy in infants. Arch Dis Child 65: 132-133, 1990.
22. Hitt MBA, Prevec FL, Graham FL. Construction and Propagation of Human Adenovirus Vectors. San Diego, CA: Academic, 1998, p. 500-512.
23. Hogan SP, Mishra A, Brandt EB, Foster PS, Rothenberg ME. A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy. Proc Natl Acad Sci USA 97: 6681-6686, 2000.
24. Hogan SP, Mishra A, Brandt EB, Royalty MP, Pope SM, Zimmermann N, Foster PS, Rothenberg ME. A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation. Nat Immun 2: 353-360, 2001.
25. Iqbal N, Oliver JR, Wagner FH, Lazenby AS, Elson CO, Weaver CT. T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med 195: 71-84, 2002.
26. Kanai T, Ilyama R, Ishikura T, Uraushihara K, Totsuka T, Yamazaki M, Nakamuma T, Watanabe M. Role of the innate immune system in the development of chronic colitis. J Gastroenterol 37, Suppl 14: 38-42, 2002.
27. Kelly KJ. Eosinophilic gastroenteritis. J Pediatr Gastroenterol Nutr 30, Suppl: S28-S35, 2000.
28. Kelly KJ, Lazenby AJ, Rowe PC, Yardley JH, Perman JA, Sampson HA. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology 109: 1503-1512, 1995.
29. Kweon MN, Yamamoto M, Kajiki M, Takahashi I, Kiyono H. Systemically derived large intestinal CD4(+-) Th2 cells play a central role in STAT6-mediated allergic diarrhea. J Clin Invest 106: 199-206, 2000.
30. Lampinen M, Carlson M, Sangfelt P, Taha Y, Thorn M, Loof L, Raab Y, Venge P. IL-5 and TNF-alpha participate in recruitment of eosinophils to intestinal mucosa in ulcerative colitis. Dig Dis Sci 46: 2004-2009, 2001.
31. Leinbach GE, Rubin CE. Eosinophilic gastroenteritis: a simple reaction to food allergens? Gastroenterology 59: 874-889, 1970.
32. Maluenda C, Phillips AD, Briddon A, Walker-Smith JA. Quantitative analysis of small intestinal mucosa in cow's milk-sensitive enteropathy. J Pediatr Gastroenterol Nutr 3: 349-356, 1984.
33. Mishra A, Hogan SP, Brandt EB, Rothenberg ME. An etiological role for aeroallergens and eosinophils in experimental esophagitis. J Clin Invest 107: 83-90, 2001.
34. Mishra A, Hogan SP, Brandt EB, Rothenberg ME. Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin. Blood 96: 1538-1544, 2000.
35. Mishra A, Hogan SP, Lee JJ, Foster PS, Rothenberg ME. Fundamental signals that regulate eosinophil homing to the gastrointestinal tract. J Clin Invest 103: 1719-1727, 1999.
36. Moon A, Kleinman RE. Allergic gastroenteropathy in children. Ann Allergy Asthma Immunol 74: 5-12; quiz 12-16, 1995.
37. Mould AW, Matthaei KI, Young IG, Foster PS. Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. J Clin Invest 99: 1064-1071, 1997.
38. Moyron-Quiroz JE, Rangel-Moreno J, Kusser K, Hartson L, Sprague F, Goodrich S, Woodland DL, Lund FE, Randall TD. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat Med 10: 927-934, 2004.
39. Nishitani H, Okabayashi M, Satomi M, Shimoyama T, Dohi Y. Infiltration of peroxidase-producing eosinophils into the lamina propria of patients with ulcerative colitis. J Gastroenterol 33: 189-195, 1998.
40. Odze RD, Wershil BK, Leichtner AM, Antonioli DA. Allergic colitis in infants. J Pediatr 126: 163-170, 1995.
41. Ohkawara Y, Lei XF, Stampfli MR, Marshall JS, Xing Z, Jordana M. Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation. Am J Respir Cell Mol Biol 16: 510-520, 1997.
42. Owen RL, Piazza AJ, Ermak TH. Ultrastructural and cytoarchitectural features of lymphoreticular organs in the colon and rectum of adult BALB/c mice. Am J Anat 190: 10-18, 1991.
43. Pensabene L, Brundler MA, Bank JM, Di Lorenzo C. Evaluation of mucosal eosinophils in the pediatric colon. Dig Dis Sci 50: 221-229, 2005.
44. Perry GA, Sharp JG. Characterization of proximal colonic lymphoid tissue in the mouse. Anat Rec 220: 305-312, 1988.
45. Rothenberg ME. Eosinophilia. N Engl J Med 338: 1592-1600, 1998.
46. Rothenberg ME, Mishra A, Brandt EB, Hogan SP. Gastrointestinal eosinophils. Immunol Rev 179: 139-155, 2001.
47. Rudolphi A, Bonhagen K, Reimann J. Polyclonal expansion of adoptively transferred CD4-+ alpha beta T cells in the colonic lamina propria of scid mice with colitis. Eur J Immunol 26: 1156-1163, 1996.
48. Saavedra-Delgado AM, Metcalfe DD. Interactions between food antigens and the immune system in the pathogenesis of gastrointestinal diseases. Ann Allergy 55: 694-702, 1985.
49. Sherman MP, Cox KL. Neonatal eosinophilic colitis. J Pediatr 100: 587-589, 1982.
50. Shi HZ, Humbles A, Gerard C, Jin Z, Weller PF. Lymph node trafficking and antigen presentation by endobronchial eosinophils. J Clin Invest 105: 945-953, 2000.
51. Stampfli MR, Wiley RE, Neigh GS, Gajewska BU, Lei XF, Snider DP, Xing Z, Jordana M. GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. J Clin Invest 102: 1704-1714, 1998.
52. Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut 31: 54-58, 1990.
53. Walsh RE, Gaginella TS. The eosinophil in inflammatory bowel disease. Scand J Gastroenterol 26: 1217-1224, 1991.
54. Weller PF. The immunobiology of eosinophils. N Engl J Med 324: 1110-1118, 1991.
55. Wirtz S, Galle PR, Neurath MF. Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure. Gut 44: 800-807, 1999.
56. Yang PC, Jury J, Soderholm JD, Sherman PM, McKay DM, Perdue MH. Chronic psychological stress in rats induces intestinal sensitization to luminal antigens. Am J Pathol 168: 104-114; quiz 363, 2006.
57. Yeung MM, Melgar S, Baranov V, Oberg A, Danielsson A, Hammarstrom S, Hammarstrom ML. Characterisation of mucosal lymphoid aggregates in ulcerative colitis: immune cell phenotype and TcR-gamma-delta expression. Gut 47: 215-227, 2000.
58. Yoshida M, Shirai Y, Watanabe T, Yamori M, Iwakura Y, Chiba T, Kita T, Wakatsuki Y. Differential localization of colitogenic Th1 and Th2 cells monospecific to a microflora-associated antigen in mice. Gastroenterology 123: 1949-1961, 2002.