Evaluation on antagonist activities of polycyclic aromatic hydrocarbons using the yeast two-hybrid detection system for endocrine disruptors

Environmental Monitoring and Assessment

Volumn 129, Issue 1-3, 2007, Pages 87-95

  Lee, Haeng Seog ^a   Cho, Eun Min ^b   Jung, Jae Hak ^c   Ohta, Akinori ^d  

^a Anyang University   (South Korea)

^b UNIVERSITY OF FLORIDA   (United States)

^c Yeungnam University   (South Korea)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Agonist and antagonist; Co activator SRC1; Endocrine disrupters; HER LBD; PAHs; Yeast two hybrid detection system

Indexed keywords

BIOACTIVITY; BIOASSAY; ENZYME INHIBITION; GENES; YEAST;

ENDOCRINE DISRUPTOR; HUMAN ESTROGEN RECEPTOR; LIGAND BINDING DOMAIN; REPORTER GENE INDUCTION; TRANSCRIPTIONAL ACTIVATION;

POLYCYCLIC AROMATIC HYDROCARBONS;

4 HYDROXYTAMOXIFEN; ANTHRACENE; ANTIESTROGEN; BETA GALACTOSIDASE; CAMPHOR; CARBAZOLE DERIVATIVE; COUMESTROL; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN RECEPTOR BETA; ESTRONE; FLUORENE; FULVESTRANT; GENISTEIN; NICOTINE; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBON; STEROID RECEPTOR COACTIVATOR 1; TESTOSTERONE;

ANTAGONISM; ENDOCRINE DISRUPTOR; LIGAND; PAH; YEAST;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE CONTROL; LIGAND BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RELIABILITY; REPORTER GENE; SCREENING TEST; TOXICITY TESTING; TRANSCRIPTION INITIATION; TWO HYBRID SYSTEM;

ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR BETA; KOREA; POLYCYCLIC HYDROCARBONS, AROMATIC; TWO-HYBRID SYSTEM TECHNIQUES; WATER MICROBIOLOGY;

EID: 34547119092     PISSN: 01676369     EISSN: 15732959     Source Type: Journal    
DOI: 10.1007/s10661-006-9430-3     Document Type: Article

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