Enhanced production of ε-caprolactone by overexpression of NADPH-regenerating glucose 6-phosphate dehydrogenase in recombinant Escherichia coli harboring cyclohexanone monooxygenase gene

Applied Microbiology and Biotechnology

Volumn 76, Issue 2, 2007, Pages 329-338

  Lee, Won Heong ^a   Park, Jin Byung ^b   Park, Kyungmoon ^c   Kim, Myoung Dong ^d   Seo, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b Ewha Womans University   (South Korea)

^c Hong Ik University   (South Korea)

^d Kangwon National University   (South Korea)

Author keywords

Cyclohexanone monooxygenase; Escherichia coli; Fed batch; Glucose 6 phosphate dehydrogenase; NADPH; Substrate product inhibition

Indexed keywords

COEXPRESSION; CYCLOHEXANONE MONOOXYGENASE; GLUCOSE 6-PHOSPHATE DEHYDROGENASE; SUBSTRATE/PRODUCT INHIBITION;

BIOCONVERSION; CELL CULTURE; ENZYME KINETICS; ESCHERICHIA COLI; GENE ENCODING; GENE EXPRESSION;

KETONES;

CYCLOHEXANONE; CYCLOHEXANONE MONOOXYGENASE; EPSILON CAPROLACTONE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; LACTONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; CAPROLACTONE; CYCLOHEXANONE DERIVATIVE; CYCLOHEXANONE OXYGENASE; ESCHERICHIA COLI PROTEIN; HEXANOIC ACID DERIVATIVE; LACTONE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGENASE; RECOMBINANT PROTEIN;

BACTERIUM; COLIFORM BACTERIUM; ENZYME ACTIVITY; ESTER; GENE EXPRESSION; OXIDATION; SUBSTRATE;

ACINETOBACTER CALCOACETICUS; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL METABOLISM; BAEYER VILLIGER REACTION; BIOTRANSFORMATION; CELL METABOLISM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ESCHERICHIA COLI; FED BATCH CULTURE; GENE OVEREXPRESSION; NONHUMAN; PROTEIN EXPRESSION; BIOREACTOR; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC ENHANCEMENT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; METHODOLOGY; PROTEIN ENGINEERING;

ACINETOBACTER CALCOACETICUS; ESCHERICHIA COLI;

BIOREACTORS; CYCLOHEXANONES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC ENHANCEMENT; GLUCOSEPHOSPHATE DEHYDROGENASE; HEXANOIC ACIDS; LACTONES; NADP; OXYGENASES; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 34547114478     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-007-1016-7     Document Type: Article

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