Nt mutation causing laterality defects associated with deletion of rotatin

Mammalian Genome

Volumn 18, Issue 5, 2007, Pages 310-315

  Chatterjee, Bishwanath ^a   Richards, Katharina ^a   Bucan, Maja ^b   Lo, Cecilia ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CD226 GENE; CHROMOSOME 18; CHROMOSOME WALKING; DOK6 GENE; EMBRYO; FEMALE; GENE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENETIC TRANSCRIPTION; GENOME; HEMISPHERIC DOMINANCE; HNF3BETA GENE; MALE; MICROSATELLITE MARKER; MOUSE; MUTANT; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RTTN GENE; TXNDC10;

ANIMALS; BODY PATTERNING; CHROMOSOMES, MAMMALIAN; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, LETHAL; MEMBRANE PROTEINS; MICE; MICROSATELLITE REPEATS; MUTATION;

MUS; MUS MUSCULUS CASTANEUS;

EID: 34547108813     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-007-9023-7     Document Type: Article

References (23)

1. Collignon J, Varlet I, Robertson EJ (1996) Relationship between asymmetric nodal expression and direction of embryonic turning. Nature 381:155-158
2. Crowder RJ, Enomoto H, Yang M, Johnson EM Jr,Milbrandt J (2004) Dok-6. A novel p62 Dok family member, promotes ret-mediated neurite outgrowth. J Biol Chem 279:42072-42081
3. Faisst AJM, Alvarez-Bolado G, Treichel D, Gruss P (2002) Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos. Mech Dev 113:15-28
4. Haugstetter J, Blicher T, Ellgaard L (2005) Identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum. J Biol Chem 280:8371-8380
5. Hirokawa N, Tanaka Y, Okada Y, Takeda S (2006) Nodal flow and the generation of left-right asymmetry. Cell 125:33-45
6. Izraeli S, Lowe KA, Bertness VL, Good DJ, Dorward DW, et al. (1999) The SIL gene is required for mouse embryonic axial development and left-right specification. Nature 399:691-694
7. Jian JL, Zhu CS, Xu ZW, Ouyang WM, Ma DC, et al. (2006) Identification and characterization of the CD226 gene promoter. J Biol Chem 281:28731-28736
8. Loots GG, Ovcharenko I, Pachter L, Dubchak I, Rubin EM (2002) rVISTA for comparative sequence-based discovery of transcription factor binding sites. Genome Res 12:832-839
9. Lowe LA, Supp DM, Smapath K, Yokoyama T, Wright CV, et al. (1996) Conserved left-right asymmetry of nodal expression and alternations in murine situs inversus. Nature 381:158-161
10. Lowe LA, Yamada S, Kuehn MR (2001) Genetic dissection of nodal function in patterning the mouse embryo. Development 128:1831-1843
11. Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS (1999) Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A 96:5043-5048
12. Melloy PG, Ewart JL, Cohen MF, Desmond ME, Kuehn MR, et al. (1997) No turning, a mouse mutation causing left right and axial patterning defects. Dev Biol 193:77-89
13. Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, et al. (1998) lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 94:287-297
14. Mercola M, Levin M (2001) Left-right asymmetry determination in vertebrates. Cell 17:779-805
15. Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, et al. (2000) The oak ridge polycystic kidney (orpk) disease gene is required for left-right axis determination. Development 127:2347-2355
16. Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, et al. (1998) Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extra embryonic fluid in mice lacking KIF3B motor protein. Cell 95:829-837
17. Nonaka S, Yoshiba S, Watanabe D, Ikeuchi S, Goto T, et al. (2005) De novo formation of left-right asymmetry by posterior tilt of nodal cilia. PloS Biol 3:e268
18. Okada Y, Takeda S, Tanaka Y, Belmonte JC, Hirokawa N (2005) Mechanism of nodal flow: A conserved symmetry breaking event in left right axis determination. Cell 121:633-644
19. Roebroek AJM, Umans L, Pauli IGL, Robertson EJ, Leuven FV, et al. (1998) Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development 125:4863-4876
20. Shiratori H, Hamada H (2006) The left-right axis in mouse: from origin to morphology. Development 133:2095-2104
21. Takeda S, Yonekawa Y, Tanaka Y, Okada Y, Nonaka S, et al. (1999) Left-right asymmetry and kinesis superfamily protein KIF3A: A new insight in determination of laterality and mesoderm induction by KIF3A-/- mice analysis. J Cell Biol 145:825-836
22. Yost HJ (2001) Establishment of left-right asymmetry. Int Rev Cytol 203:357-381
23. Zhao M, Janas JA, Niki M, Pandolfi PP, Aelst LV (2006) Dok-1 independently attenuates Ras/mitogen-activated protein kinase and src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Mol Cell Biol 26:2479-2489