Nitric oxide in the cardiovascular and pulmonary circulation - A brief review of literatures and historical landmarks

Chinese Journal of Physiology

Volumn 50, Issue 2, 2007, Pages 43-50

  Chen, Hsing I ^a   Chang, Huai Ren ^a   Wu, Chia Yen ^a   Kao, Shang Jyh ^b   Wang, David ^c   Hsieh, Nan Kuang ^d   Hsu, Yung Hsiang ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d Tao Yuan Army Hospital   (Taiwan)

Author keywords

Endothelial factors; Hypertension; Nitric oxide; Pulmonary edema; Vascular changes; Ventricular hypertrophy

Indexed keywords

ACETYLCHOLINE; INDUCIBLE NITRIC OXIDE SYNTHASE; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; BRAIN BLOOD FLOW; CARDIOPULMONARY HEMODYNAMICS; DISEASE COURSE; ENDOTHELIAL DYSFUNCTION; EPIDEMIC ENCEPHALITIS; HEART VENTRICLE HYPERTROPHY; HISTORY OF MEDICINE; HUMAN; HYPERTENSION; LUNG EDEMA; NONHUMAN; PATHOPHYSIOLOGY; PRESSORECEPTOR; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SEPSIS; VASCULAR RESISTANCE; VASODILATATION; ANIMAL; CARDIOVASCULAR FUNCTION; LUNG CIRCULATION; PHYSIOLOGY; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR ENDOTHELIUM;

ANIMALS; CARDIOVASCULAR PHYSIOLOGY; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION; NITRIC OXIDE; PULMONARY CIRCULATION; PULMONARY EDEMA; RATS; RATS, INBRED SHR; SEPSIS; VASODILATION;

EID: 34547107325     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Review

References (100)

1. Arnal, J.F., el Amrani, A.I.E., Chatellier, G., Menard, J. and Michel, J.B. Cardiac weight ill hypertension induced by nitric oxide synthase blockade. Hypertension 22: 380-387, 1993.
2. Bone, R.C., Grodzin, C.J. and Balk, R.A. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 112: 235-243, 1997.
3. Chang, C.L., Yeh, F.C., Ho, W. and Chen, H.I. Effects of sodium nitroprusside-induced hypotension on the cerebral and hindlimb blood flow in dogs. Proc. Natl. Sci. Counc. 9: 202-207, 1985.
4. Chang, H.R., Lee, R.P., Wu, C.Y. and Chen, H.I. Nitric oxide in mesenteric vascular reactivity: a comparison between rats with normotension and hypertension. Clin. Exp. Pharmacol. Physiol. 29: 275-280, 2002.
5. Chang, H.R., Wu, C.Y. and Chen, H.I. Arterial pressure following chronic blockade of endogenous nitric oxide in normotensive and hypertensive rats. Tzu Chi Med. J. 11: 41-50, 1999.
6. Chang, H.R., Wu, C.Y., Hsu, Y.H. and Chen, H.I. Reduction of ventricular hypertrophy and fibrosis in spontaneously hypertensive rats by L-arginine. Chinese J. Physiol. 48: 15-22, 2005.
7. Chang, K.C., Hsieh, K.S., Kuo, T.S. and Chen, H.I. Effects of nifedipine on systemic hydraulic vascular load in patients with hypertension. Cardiovasc. Res. 24: 719-726, 1990.
8. Chang, K.C., Hsieh, K.C., Kuo, T.S. and Chen, H.I. Quantitation and characterization of ventricular afterload by arterial impedance analysis. J. Med. Sci. 10: 61-66, 1989.
9. Chen, H.I. Effects of nitroglycerin and hydralazine on the vascular resistance and capacitance of the splanchnic circulation in dogs. Proc. Natl. Sci. Counc. (ROC) 2: 367-372, 1978.
10. Chen, H.I., Chapleau, M.W., McDowell, T.S. and Abboud, F.M. Prostaglandins contribute to activation of baroreceptors in rabbits. Possible paracrine influence of endothelium. Circ. Res. 67: 1394-1404, 1990.
11. Chen, H.I., then, S.J. and Cheng, C.F. Direct and reflex effects of nitroglycerin on the blood volume distribution, evaluated by regional weighing in the cat. J. Pharm. Pharmacol. 31: 810-813, 1979.
12. Chen, H.I. and Yang, Y.L. Structural and functional changes in the kidney and other organs in hypertensive rats following chronic nitric oxide deprivation. (Submitted for publication in Cardiovasc. Res., 2006)
13. Chen, H.I. and Hu, C.T. Endogenous nitric oxide on arterial hemodynamics: a comparison between normotensive and hypertensive rats. Am. J. Physiol. 273: H1816-H1823, 1997.
14. Chen, H.I., Hu, C.T., Wu, C.Y. and Wang, D. Nitric Oxide in systemic and pulmonary hypertension. J. Biomed. Sci. 4: 244-248, 1997.
15. Chen, H.I., Huang, H.S., Yang, J.G. and Wang, D. Vasodilator and oxidant scavenger in the neurogenic pulmonary edema induced by cerebral injury. Chinese J. Physiol. 35: 123-131, 1992.
16. Chen, H.I., Kao, S.J., Wang, D., Lee, R.P. and Su, C.F. Acute respiratory distress syndrome. J. Biomed. Sci. 10: 588-592, 2003.
17. Chen, H.I., Liao, J.F., Kuo, L. and Ho, S.T. Centrogenic pulmonary hemorrhagic edema induced by cerebral compression in rats. Mechanism of volume and pressure loading in the pulmonary circulation. Circ. Res. 47: 366-373, 1980.
18. Chen, H.I., Sun, S.C. and Chai, C.Y. Pulmonary edema and hemorrhage resulting from cerebral compression. Am. J. Physiol. 224: 223-229, 1973.
19. Chen, H.I., Yeh, D.Y., Liou, H.L. and Kao, S.J. Insulin attenuates endotoxin-induced acute lung injury in conscious rats. Crit. Care Med. 34: 758-764, 2006.
20. Chen, H.I., Yeh, F.C. and Ho, W. Direct effects of nitroglycerin on the resistance, exchange and capacitance functions of the canine intestinal vasculature. J. Pharmacol. Exp. Ther. 218: 497-503, 1981.
21. Chen, S.J. and Chen, H.I. Clinical pharmacology of antihypertensive drugs. (A brief review in Chinese) Med. Sci. 3: 911-918, 1979.
22. Chou, C,L., Chen, H.I., Hsu, K., Li, M.H. and Wang, D. Dimethylthiourea decreases acute pulmonary edema induced by phorbol myristate acetate in isolated blood-perfused lung of the rat. Proc. Natl. Sci. Counc. 14: 33-39, 1990.
23. Culotta, E. and Koshland, D.E. Molecule of the year: NO news is good news. Science 258: 1862-1865, 1992.
24. de Belder, A. and Moncada, S. Cardiomyopathy: a role for nitric oxide? Int. J. Cardiol. 50: 263-268, 1995.
25. de Belder, A.J., Radomski, M.W., Martin, J.F. and Moncada, S. Nitric oxide and the pathogenesis of heart muscle disease. Eur. J. Clin. Invest. 25: 1-8, 1995.
26. Dugas, B., Debre, P. and Moncada, S. Nitric oxide, a vital poison inside the immune and inflammatory network. Res. Immunol. 146: 664-670, 1995.
27. Dusting, G.J., Macdonald, P.S., Higgs, E.A. and Moncada, S. The endogenous nitrovasodilator produced by the vascular endothelium. Aust. N. Z. J. Med. 19: 493-498, 1989.
28. Forstermann, U., Schmidt, H.H., Pollock, J.S., Sheng, H., Mitchell, J.A., Warner, T.D., Nakane, M. and Murad, F. Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem. Pharmacol. 42: 1849-1857, 1991.
29. Furchgott, R.F. Role of endothelium in responses of vascular smooth muscle. Circ. Res. 53: 557-573, 1983.
30. Furchgott, R.F. The role of endothelium in the responses of vascular smooth muscle to drugs. Ann. Rev. Pharmacol. Toxicol. 24: 175-197, 1984.
31. Furchgott, R.F. The 1989 Ulf von Euler lecture. Studies on endothelium-dependent vasodilatiun and the endothelium-derived relaxing factor. Acta. Physiol. Scand. 139: 257-270, 1990.
32. Furchgott, R.F. Endothelium-dependent relaxation, endothelium-derived relaxing factor and photorelaxation of blood vessels. Semin. Perinatol. 15: 11-15, 1991.
33. Furchgott, R.F. Introduction to EDRF research. J. Cardiovasc. Pharmacol. 22: S1-S2, 1993.
34. Furchgott, R.F., Cherry, P.D., Zawadzki, J.V. and Jothianandan, D. Endothelial cells as mediators of vasodilation of arteries. J. Cardiovasc. Pharmacol. 6: S336-S343, 1984.
35. Furchgott, R.F. and Vanhoutte, P.M. Endothelium-derived relaxing and contracting factors. FASEB J. 3: 2007-2018, 1989.
36. Furchgott, R.F. and Zawadzki, J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1980.
37. Hsieh, N.K., Wang, J.Y., Liu, J.C., Lee, W.H. and Chen, H.I. Structural changes in cerebral arteries following nitric oxide deprivation: a comparison between normotensive and hypertensive rats. Thromb. Haemost. 92: 162-170, 2004.
38. Hsieh, N.K., Wang, J.Y., Liu, J.C., Wang, S.D. and Chen, H.I. Nitric oxide inhibition accelerates hypertension and induces perivascular inflammation in rats. Clin. Exp. Pharmacol. Physiol. 31: 212-218, 2004.
39. Hsu, B.G., Yang, F.L., Lee, R.P., Peng, T.C. and Chen, H.I. Effects of posttreatment with law dose propofol on inflammatory responses to lipopolysaccharide-induced shock in conscious rats. Clin. Exp. Pharmacol. Physiol. 32: 24-29, 2005.
40. Hsu, B.G., Yang, F.L., Lee, R.P., Peng, T.C., Harn, H.J. and Chen, H.I. N-Acetylcysteine ameliorates lipopolysaccharide-induced organ damage in conscious rats. J. Biomed. Sci. 11: 152-162, 2004.
41. Hsu, K., Wang, D., Chang, M.L., Wu, C.P. and Chen, H.I. Pulmonary edema induced by phorbol myristate acetate is attenuated by compounds that increase intracellular cAMP. Res. Exp. Med. 196: 17-28, 1996.
42. 2 in rats. J. Appl. Physiol. 76: 545-552, 1994.
43. Hsu, Y.H., Kao, S.J., Lee, R.P. and Chen, H.I. Acute pulmonary oedema: rare causes and possible mechanisms. Clin. Sci. 104: 259-264, 2003.
44. Hu, C.T., Chang, H.R., Hsu, Y.H., Liu, C.J. and Chen, H.I. Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats. Life Sci. 78: 164-173, 2005.
45. Hu, C.T., Chang, K.C., Wu, C.Y. and Chen, H.I. Acute effects of nitric oxide blockade with L-NAME on arterial haemodynamics in the rat. Brit. J. Pharmacol. 122: 1237-1243, 1997.
46. Ignarro, L.J. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ. Res. 65: 1-21, 1989a.
47. Ignarro, L.J. Endothelium-derived nitric oxide: actions and properties. FASEB J. 3: 31-36, 1989b.
48. Ignarro, L.J. Endothelium-derived nitric oxide: pharmacology and relationship to the actions of organic nitrate esters. Pharm. Res. 6: 651-659, 1989c.
49. Ignarro, L.J. Heme-dependent activation of soluble guanylate cyclase by nitric oxide: regulation of enzyme activity by porphyrins and metalloporphyrins. Semin. Hematol. 26: 63-76, 1989d.
50. Ignarro, L.J. Biosynthesis and metabolism of endothelium-derived nitric oxide. Ann. Rev. Pharmacol. Toxicol. 30: 535-560, 1990a.
51. Ignarro, L.J. Haem-dependent activation of guanylate cyclase and cyclic GMP formation by endogenous nitric oxide: a unique transduction mechanism for transcellular signaling. Pharmacol. Toxicol. 67: 1-7, 1990b.
52. Ignarro, L.J. Nitric oxide. A novel signal transduction mechanism for transcellular communication. Hypertension 16: 477-483, 1990c.
53. Ignarro, L.J. Heme-dependent activation of guanylate cyclase by nitric oxide: a novel signal transduction mechanism. Blood Vessels 28: 67-73, 1991a.
54. Ignarro, L.J. Signal transduction mechanisms involving nitric oxide. Biochem. Pharmacol. 41: 485-490, 1991b.
55. Ignarro, L.J., Buga, G.M., Wood, K.S., Byrns, R.E. and Chandhuri, G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA 84: 9265-9269, 1987.
56. Ignarro, L.J., Ross, G. and Tillisch, J. Pharmacology of endothelium-derived nitric oxide and nitrovasodilators. Western J. Med. 154: 51-62, 1991.
57. Kao, S.J., Peng, T.C., Lee, R.P., Hsu, K., Chen, C.F., Hung, Y.K., Wang, D. and Chen, H.I. Nitric oxide mediates lung injury induced by ischemia-reperfusion in rats. J. Biomed. Sci. 10: 58-64, 2003.
58. Kao, S.J., Wang, D., Yeh, D.Y., Hsu, K., Hsu, Y.H. and Chen, H.I. Static inflation attenuates ischemia/reperfusion injury in an isolated rat lung in situ. Chest 126: 552-558, 2004a.
59. Kao, S.J., Wei, J., Hwang, C.P., Lieu, M.W., Jiang, J.S., Wang, D. and Chen, H.I. Modulatory effect of blood cells on hypoxic vasoconstriction response and nitric oxide release in rat lungs. J. Formos. Med. Assoc. 98: 39-44, 1999.
60. Kao, S.J., Yang, F.L., Hsu, Y.H. and Chen, H.I. Mechanism of fulminant pulmonary edema caused by enterovirus 71. Clin. Infect. Dis. 38: 1784-1788, 2004b.
61. Kao, S.J., Su, C.F., Liu, D.D. and Chen, H.I. Endotoxin-induced acute lung injury and organ dysfunction are attenuated by pentobarbital anaesthesia. Clin. Exp. Pharmacol. Physiol. 34: 480-487, 2007.
62. Lee, C.C., Lin, N.T., Hsu, Y.H. and Chen, H.I. Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats. J. Cardiovas. Pharmacol. 45: 396-403, 2005.
63. Lee, R.P., Wang, D., Kao, S.J. and Chen, H.I. The lung is the major site that produces nitric Oxide to induce acute pulmonary oedema in endotoxin shock. Clin. Exp. Pharmacol. Physiol. 28: 315-320, 2001.
64. Lee, R.P., Wang, D., Lin, N.T. and Chen, H.I. Physiological and chemical indicators for early and late stages of sepsis in conscious rats. J. Biomed. Sci. 9: 613-621, 2002.
65. Lee, R.P., Wang, D., Lin, N.T., Chou, Y.W. and Chen, H.I. A modified technique for tail cuff pressure measurement in unrestrained conscious rats. J. Biomed. Sci. 9: 424-427, 2002.
66. Lin, H.I., Chu, S.J., Wang, D., Chen, H.I. and Hsu, K. Effects of an endogenous nitric oxide synthase inhibitor on phorbol myristate acetate-induced acute lung injury in rats. Clin. Exp. Pharmacol. Physiol. 3: 393-398, 2003.
67. Liu, D.M., Yang, C.C., Lee, R.P. and Chen, H.I. Opposition of rapid baroreceptor resetting by prostanoids ia rabbits. Chinese J. Physiol. 43: 15-21, 2000.
68. Liu, D.M., Yeh, F.C. and Chen, H.I. Pressure-dependent tissue bleeding in cutaneous flap during nitroprusside infusion in the dog. Chinese J. Physiol. 32: 93-101, 1989.
69. Lopez-Jaramillo, P., Teran, E. and Moncada, S. Calcium supplementation prevents pregnancy-induced hypertension by increasing the production of vascular nitric oxide. Med. Hypotheses 45: 68-72, 1995.
70. Lorente, J.A., Landin, L., De Pablo, R., Renes, E. and Liste, D. L-arginine pathway in the sepsis syndrome. Crit. Care Med. 21: 1287-1295, 1993.
71. Moncada, S. Nitric oxide. J. Hypertens. Suppl. 12: S35-S39, 1994.
72. Moncada, S. "Ottorino Rossi" Award 1997. The biology of nitric oxide. Funct. Neurol. 12: 134-140, 1997a.
73. Moncada, S. Nitric oxide in the vasculature: physiology and pathophysiology. Ann. NY Acad. Sci. 811: 60-67, 1997b.
74. Moncada, S., Higgs, A. and Furchgott, R. *IV. International Union of Pharmacology Nomenclature in Nitric Oxide Research. Pharmacol. Rev. 49: 137-142, 1997.
75. Moncada, S. and Higgs, E.A. Metabolism of arachidonic acid. Ann. NY Acad. Sci. 522: 454-463, 1988.
76. Moncada, S. and Higgs, E.A. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 9: 1319-1330, 1995.
77. Moncada, S., Palmer, R.M. and Higgs, E.A. Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication. Biochem. Pharmacol. 38: 1709-1715, 1989a.
78. Moncada, S., Palmer, R.M. and Higgs, E.A. The biological significance of nitric oxide formation from L-arginine. Biochem. Soc. Trans. 17: 642-644, 1989b.
79. Moncada, S., Palmer, R.M. and Higgs, E.A. Relationship between prostacyclin and nitric oxide in the thrombotic process. Thromb. Res. Suppl. 11: 3-13, 1990.
80. Moncada, S., Palmer, R.M. and Higgs, E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142, 1991.
81. Moncada, S., Radomski, M.W. and Palmer, R.M. Endothelium-derived relaxing factor. Identification as nitric oxide and role in the control of vascular tone and platelet function. Biochem. Pharmacol. 37: 2495-2501, 1988.
82. Munford, R.S. Sepsis and septic shock. In: Wilson J.D., Braunwald, E., Isselbacher, KJ. (eds). Harrison's Principles of Internal Medicine, 14th edn. McGraw-Hill, New York 776-780, 1997.
83. Murad, F. Role of cyclic GMP in the mechanism of action of nitrovasodilators, endothelium-dependent agents and atrial natriuretic peptide. Biochem. Soc. Trans. 16: 490-492, 1988.
84. Murad, F., Forstermann, U., Nakane, M., Pollock, J., Tracey, R., Matsumoto, T. and Buechler, W. The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular communication. Adv. Second Messenger Phosphoprotein Res. 28: 101-109, 1993.
85. Murad, F., Forstermann, U., Nakane, M., Schmidt, H., Pollock, J., Sheng, H., Matsumoto, T., Warner, T., Mitchell, J. and Tracey, R. The nitric oxide-cyclic GMP signal transduction pathway in vascular smooth muscle preparations and other tissues. Jpn. J. Pharmacol. 58: 150P-157P, 1992.
86. Murad, F., Leitman, D., Waldman, S., Chang, C.H., Hirata, M. and Kohse, K. Effects of nitrovasodilators, endothelium-dependent vasodilators, and atrial peptides on cGMP. Cold Spring Harb. Symp. Quant. Biol. 53: 1005-1009, 1988.
87. Palmer, R.M., Ferrige, A.G. and Moncada, S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526, 1987.
88. Parrillo, J.E. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 328: 1471-1477, 1993.
89. Ribeiro, M.O., Antunes, E., de Nucci, G., Lovisolo, S.M. and Zatz, R. Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension. Hypertension 20: 298-303, 1992.
90. 2+ /calmodulin-regulated nitric oxide synthases. Cell Calcium 13: 427-434, 1992.
91. Szabo, C., Mitchell, J.A., Thiemermann, C. and Vane, J.R. Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Brit. J. Pharmacol. 108: 786-792, 1993.
92. Waldman, S.A. and Murad, F. Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system. J. Cardiovasc. Pharmacol. 12: Sl15-S118, 1988.
93. Wang, D., Chou, C.L., Hsu, K. and Chen, H.I. Cyclooxygenase pathway mediates lung injury induced by phorbol and platelets. J. Appl. Physiol. 70: 2417-2421, 1991.
94. Wang, D., Hsu, K., Hwang, C.P. and Chen, H.I. Measurement of nitric oxide release in the isolated perfused rat lung. Biochem. Biophys. Res. Commun. 208: 1016-1020, 1995.
95. Wang, D., Li, M.H., Hsu, K., Shen, C.Y., Chen, H.I. and Lin, Y.C. Air embolism-induced lung injury in isolated rat lungs. J. Appl. Physiol. 72: 1235-1242, 1992.
96. Wang, D., Wei, J., Hsu, K., Jau, J., Lieu, M.W., Chao, T.J. and Chen, H.I. Effects of nitric oxide synthase inhibitors on systemic hypotension, cytokines and inducible nitric oxide synthase expression and lung injury following endotoxin administration in rats. J. Biomed. Sci. 6: 28-35, 1999.
97. Wang, Y.C., Wang, J.M., Fung, T.J. and Chen, H.I. Effects of nitroglycerin and nitroprusside on the pulmonary hemorrhagic edema induced by cerebral compression and epinephrine. Proc. Natl. Sci. Coun. (ROC) 9: 143-149, 1985.
98. Wheeler, A.P. and Bernard, G.R. Treating patients with severe sepsis. N. Engl. J. Med. 340: 207-214, 1999.
99. Wright, C.E., Rees, D.D. and Moncada, S. Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc. Res. 26: 48-57, 1992.
100. Yang, S.T., Koong, C.W. and Chen, H.I. Role of prostaglandins in regulation of cerebral blood flow during acute hypertension. Chinese J. Physiol. 40: 137-142, 1997.