Modulatory effect of blood cells on hypoxic vasoconstriction response and nitric oxide release in rat lungs

Journal of the Formosan Medical Association

Volumn 98, Issue 1, 1999, Pages 39-44

  Kao, Shang Jyh ^a   Wei, Jeng ^b   Hwang, Chie Ping ^c   Lieu, Mei Wun ^c   Jiang, Jiunn Song ^a   Wang, David ^b   Chen, Hsing I ^d  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Blood cells; Hypoxia; Lungs; Nitric oxide

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CELL; CARDIOVASCULAR AUTOREGULATION; CONTROLLED STUDY; HYPOXIA; LUNG HEMODYNAMICS; LUNG VASOCONSTRICTION; MALE; NONHUMAN; PATHOPHYSIOLOGY; RAT;

ANIMALS; ANOXIA; BLOOD CELLS; LUNG; MALE; NITRIC OXIDE; PULMONARY CIRCULATION; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTION;

EID: 0033061965     PISSN: 09296646     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Von Euler US, Lilkestrand G: Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol Scand 1946;112:301-20.
2. McCormack DG, Crawley DE, Evans TW: New perspectives in the pulmonary circulation and hypoxic pulmonary vasoconstriction. Pulm Pharmacol 1993;6: 97-108.
3. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathology and pharmacology. Pharmacol Rev 1991; 43:109-42.
4. Moncada S, Radomski MW, Palmer RMJ: Endothelium-derived relaxing factor: identification as nitric oxide and role in the control of vascular tone and platelet function. Biochem Pharmacol 1988;37:2495-501.
5. Wang D, Hsu K, Chen HI: Measurement of nitric oxide release in the isolated perfused rat lung. Biochem Biophys Res Commun 1995;208:1016-20.
6. Palmer RMJ, Ashton DS, Moncada S: Vascular endothelium cells synthesize nitric oxide from L-arginine. Nature 1988;333:664-6.
7. Hibbs JB, Taintor RR, Vavrin Z: L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in the target cells. J Immunol 1987;138:550-65.
8. McCall TB, Boughton-Smith NK, Palmer RMJ, et al: Synthesis of nitric oxide from L-arginine by neutrophils. Biochem. J 1989;261:293-6.
9. Radomski MW, Palmer RMJ, Moncada S: Characterization of the L-arginine:nitric oxide pathway in human platelets. Br J Pharmacol 1990;101:325-8.
10. Westenberger U, Thanners S, Ruf HH, et al: Formation of free radicals and nitric oxide derivative of hemoglobin in rats during shock syndrome. Free Rad Res Commun 1990;11:167-78.
11. Martin W, Vilanni GM, Jothiander D, et al: Selective blockade of endothelium-dependent and glycerol trinitrate-induced relaxation by hemoglobin and methylene blue in rabbit aorta. J Pharmacol Exp Ther 1985;232: 708-16.
12. Wang D, Chou CL, Hsu K, et al: Cyclo-oxygenase pathway mediates lung injury induced by phorbol and platelets. J Appl Physiol 1991;70:2417-21.
13. Cornfield DN, McQueston JA, McMurtry IF, et al: Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus. Am J Physiol 1992;262: H1474-81.
14. Wright CD, Mulsch A, Busse R, et al: Generation of nitric oxide by human neutrophils. Biochem Biophys Res Commun 1989;160:813-9.
15. Rimele TJ, Sturm RJ, Adams LM, et al: Interaction of neutrophils with vascular smooth muscle: identification of a neutrophil-derived relaxing factor. J Pharmacol Exp Ther 1988;245:102-11.
16. Salvemini D, Nucci GD, Gryglewski RJ, et al: Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci USA 1989;86:6328-32.
17. Vaage J, Bo G, Hognestad J: Pulmonary responses to intravascular platelet aggregation in the cat. Acta Physiol Scand 1974;92:546-56.
18. Vaage J, Nicolaysen G, Waaler BA: Aggregation of blood platelets and increased hydraulic conductivity of pulmonary exchange vessels. Acta Physiol Scand 1976;98:175-84.
19. Weir EK, Seavy J, Mlczoch J, et al: Platelets are not essential for the pulmonary vascular pressor response to hypoxia. J Lab Clin Med 1975;88:412-6.
20. Hauge A, Melmon KL: Role of histamine in hypoxic pulmonary hypertension in the rat. II. Circ Res 1968;22:385-92.
21. Hauge A: Role of histamine in hypoxic pulmonary hypertension in the rat. Circ Res 1968;22:371-83.
22. Kivity S, Souhrada JF: Plasma and platelet potentiate a hypoxic vascular response of the isolated lung. J Appl Physiol 1981;51:875-80.
23. McMurtry IF, Hookway BW, Roos S: Red blood cells play a crucial role in maintaining vascular reactivity to hypoxia in isolated rat lungs. Chest 1977;71:253-6.
24. Kovach AGB, Lefer AM: Endothelial dysfunction in shock states. News Physiol Sci 1993;8:145-9.
25. Kilbourn RG, Joly G, Cashon B, et al: Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to alpha-adrenergic agents. Biochem Biophys Res Commun 1994;199:155-62.
26. Rious F, Petitclerc E, Audet R, et al: Recombinant human hemoglobin inhibits both constitutive and cytokine-induced nitric oxide-mediated relaxation of rabbit isolated aortic rings. J Cardiovasc Pharmacol 1994;24:229-37.
27. Wennmalm A, Benthin G, Petersson AS: Dependence of the metabolism of nitric oxide in healthy human whole blood on the oxygenation of its red cell hemoglobin. Br J Pharmacol 1992;106:507-8.