Physiological and chemical indicators for early and late stages of sepsis in conscious rats

Journal of biomedical science

Volumn 9, Issue 6, 2002, Pages 613-621

  Lee, R P ^a   Wang, David ^a   Lin, Nien Tsung ^a   Chen, Hsing I ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; HYDROXYL RADICAL; LIPOPOLYSACCHARIDE; NITRATE;

ANIMAL; ARTICLE; BLOOD; BLOOD ANALYSIS; BLOOD PRESSURE; CHEMICALLY INDUCED DISORDER; ENZYME ASSAY; HEART RATE; HOSPITALIZATION; LEUKOCYTE COUNT; MALE; RAT; SEPSIS; TIME; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; BLOOD CHEMICAL ANALYSIS; BLOOD PRESSURE; ENZYME TESTS; HEART RATE; HYDROXYL RADICAL; LEUKOCYTE COUNT; LIPOPOLYSACCHARIDES; MALE; NITRATES; RATS; RATS, WISTAR; SEPSIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0242279226     PISSN: 10217770     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02254989     Document Type: Article

References (34)

1. Ayala A, Evans TA, Chaudry IH. Does hepato­cellular injury in sepsis involve apoptosis? J SurgRes 76:165-173;1998.
2. Bernard C, Merval R, Esposito B, Tedgui A. Resistance to endotoxin shock in spontaneous­ly hypertensive rats. Hypertension 31:1350-1356;1998.
3. Chan CC, Hwang SJ, Lee FY, Wang SS, Chang FY, Li CP, Chu CJ, Lu RH, Lee SD. Prognostic value of plasma endotoxin levels in patients with cirrhosis. Scand J Gastroenterol 32:942­946; 1997.
4. Cowley HC, Bacon PJ, Goode HF, Webster NR, Jones JG, Menon DK. Plasma antioxidant potential in severe sepsis: a comparison of sur­vivors and non-survivors. Crit Care Med 24: 1179-1183;1996.
5. Goode HF, Cowley HC, Walker BE, Howdle PD, Webster NR. Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunc­tion. Crit Care Med 23:646-651;1995.
6. Goode HF, Webster NR. Free radical and an­tioxidant in sepsis. Crit Care Med 21:1770­1776; 1993.
7. Lee RP, Wang D, Kao SJ, Chen HI. The lung is the major site that produces nitric oxide to induce acute pulmonary edema in endotoxin shock. Clin Exp Pharmacol Physiol 28:315- 320;2001.
8. Lee RP, Wang D, Lin NT, Chen HL A modi­fied technique for tail-cuff pressure measure­ment in unrestrained rats at conscious state. J Biomed Sci 9:424-427;2002.
9. Leff JA, Parsons PE, Day CE. Serum antioxi­dants as predictors of adult respiratory distress syndrome in patients with sepsis. Lancet 341: 777-780; 1993.
10. Liu S, Adcock IM, Old RW, Bames PJ, Evans TW. Lipopolysaccharide treatment in vivo in­duces widespread tissue expression of induci­ble nitric oxide synthase mRNA. Biochem Bio- physRes Commun 196:1208-1213; 1993.
11. Lorente JA, Landin L, Pablo RD, Renes E, Liste D. E-Arginine pathway in the sepsis syn­drome. Crit Care Med 21:1287-1295; 1993.
12. Maier S, Emmanuilidis K, Entleutner M, Zantl N, Werner M, Pfeffer K, Heidecke CD. Mas­sive chemokine transcription in acute renal failure due to polymicrobial sepsis. Shock 14: 187-192;2000.
13. Moncada S, Palmer RM, Higgs EA. Nitric ox­ide: Physiology, pathophysiology, and pharma­cology. Pharmacol Rev 43:109-142; 1991.
14. Munford RS. Sepsis and septic shock. In: Wil­son, JD, Braunwald E, Isselbacher KJ, eds. Harrison’s Principles of Internal Medicine. New York, McGraw-Hill, 776-780; 1997.
15. Muscare MN, Nucci G. Simultaneous determi­nation of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-per­formance liquid chromatography with post-col­umn reactions. J Chromatogr Biomed Appl 686:157-164; 1996.
16. Nakamura K, lenaga K, Yokozawa T, Fujitsu­ka N, Oura H. Production of methyl guanidine from creatinine via cretol by active oxygen spe­cies: Analysis of the catabolism in vitro. Neph­ron 58:42-46;1991.
17. Nakatani Y, Fukui H, Kitano H, Nagamoto I, Tsujimoto T, Kuriyama S, Kikuchi E, Hoppou K, Tsujii T. Endotoxin clearance and its rela­tion to hepatic and renal disturbances in rats with liver cirrhosis. Liver 21:64-70;2001.
18. Nüssler AK, Silvio MD, Billiar TR, Hoffman RA, Geller DA, Selby R, Madariaga J, Sim­mons L. Stimulation of the nitric oxide syn­thase pathway in human hepatocytes by cyto­kines by cytokines and endotoxin. J Exp Med 176:261-264;1992.
19. Pagana KD. Diagnostic and Laboratory Test Reference. London, Mosby-Year Book Inc., 51-838;1997.
20. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 328:1471-1477;1993.
21. Peake SL, Moran JL, Leppard PL N-acetyl-£- cysteine depresses cardiac performance in pa­tients in septic shock. Crit Care Med 24:1302-1310;1996.
22. Pozsar J, Schwab R, Simon K, Fekete L, Or- govan G, Pap A. Effect of endotoxin adminis­tration on the severity of acute pancreatitis in two experimental models. Int J Pancreas 22: 31-37;1997.
23. Robbins RA, Springall DR, Warren JB, Kwon OJ, Buttery LD, Wilson AJ, Adconck IM, Rive- ros-Moreno V, Moncada S, Polak J, Barnes PJ. Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimu­lation. Biochem Biophys Res Commun 198: 835-843; 1994.
24. Salzman AL, Menconi MJ, Unno N, Ezzel RM, Casey DM, Gonzalez PK, Fink MP. Nitric oxide dilates tight junctions and depletes ATP in culture Caco-2BB intestinal epithelial mono­layers. Am J Physiol 268:G361-G373;1995.
25. Schmid-Schonbein GW, Seifige D, DeLaano FA, Shen K, Zweichach BW. Leukocyte counts and activation in spontaneously hypertensive and normotensive rats. Hypertension 17:323- 330;1991.
26. Stamler JS, Loh E, Roddy MA, Currie KE, Creager MA. Nitric oxide regulates basal sys­temic and pulmonary vascular resistance in healthy humans. Circulation 89:2035-2040; 1994.
27. Stewart TE, Valenza F, Ribeiro SP. Increased nitric oxide in exhaled gas as an early marker of lung inflammation in a model of sepsis. Am J Respir Crit Care Med 151:713-718; 1995.
28. Szabo C, Cuzzocrea B, Zingarelli B, O’Connor B, Salzman L, Endothelium dysfunction in a rat model of endotoxic shock: Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest 100:723-735; 1997.
29. Szabo C, Mitchell JA, Thiemermann C, Vane JR. Nitric oxide mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br J Phar­macol 108:786-792;1993.
30. Vaccaro MI, Dagrosa MA, Mora MI, Tiscornia OM, Sordelli DO. The effect of chronic intra­peritoneal infusion of bacterial endotoxin on exocrine pancreas function in rats. Int J Pan­creas 19:49-54; 1996.
31. Wang D, Wei J, Hsu K, Chao DE, Chen HI. Effects of nitric oxide synthase (NOS) inhibi­tors on the systemic hypotension, cytokines and inducible NOS expression and lung injury following endotoxin in rats. J Biomed Sci 6:28-35;1999.
32. Wright CE, Rees DD, Moncada S. Protective and pathological roles of nitric oxide in endo­toxin shock. Cardiovasc Res 26:48-57;1992.
33. Zapol WM, Rimar S, Gillis N, Marietta M, Bosken CH. Nitric oxide and the lung. Am J Respir Crit Care Med 149:1375-1380; 1994.
34. Zurovsky Y, Haber C. Antioxidants attenuate endotoxin-gentamicin induced acute renal fail­ure in rats. Scand J Urol Nephrol 29:147-154; 1995.