Overexpression of IL-1β by adenoviral-mediated gene transfer in the rat brain causes a prolonged hepatic chemokine response, axonal injury and the suppression of spontaneous behaviour

Neurobiology of Disease

Volumn 27, Issue 2, 2007, Pages 151-163

  Campbell, Sandra J ^a   Deacon, Rob M J ^a   Jiang, Yanyan ^a   Ferrari, Carina ^b   Pitossi, Fernando J ^b   Anthony, Daniel C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Acute phase response; Adenovirus; Behaviour and injury; Brain; IL 1 ; Rat

Indexed keywords

CHEMOKINE; INTERLEUKIN 1BETA; SERUM ALBUMIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; BEHAVIOR DISORDER; BRAIN INJURY; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DISEASE MODEL; GENE TRANSFER; LEUKOCYTE MIGRATION; LEUKOCYTOSIS; LIVER; LIVER INJURY; MALE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; VIRAL GENE DELIVERY SYSTEM; WEIGHT REDUCTION; ADENOVIRUS; ANIMAL; BIOSYNTHESIS; BLOOD BRAIN BARRIER; BRAIN; CHRONIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; MOTOR ACTIVITY; NERVE FIBER; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOVIRIDAE; ANIMALS; AXONS; BEHAVIOR, ANIMAL; BLOOD-BRAIN BARRIER; BRAIN; BRAIN INJURIES; CHEMOKINES; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER TECHNIQUES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-1BETA; LIVER; MOTOR ACTIVITY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34447641658     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.04.013     Document Type: Article

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