Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin

International Journal of Pharmaceutics

Volumn 341, Issue 1-2, 2007, Pages 114-124

  Nolan, L M A ^a   Corish, J ^a   Corrigan, O I ^a   Fitzpatrick, D ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Enhancer; Iontophoresis; Oleic acid; Salbutamol; Transdermal

Indexed keywords

DILTIAZEM; DRUG VEHICLE; FATTY ACID; LAURIC ACID; MONOACYLGLYCEROL; NICOTINE; OLEIC ACID; SALBUTAMOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TRANSPORT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IONTOPHORESIS; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ALBUTEROL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DICLOFENAC; DIFFUSION; DIFFUSION CHAMBERS, CULTURE; DILTIAZEM; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; FATTY ACIDS; GELS; HUMANS; IONTOPHORESIS; KINETICS; LAURIC ACIDS; LIQUID CRYSTALS; MICE; MICE, INBRED HRS; MODELS, BIOLOGICAL; NICOTINE; OLEIC ACID; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SKIN; SKIN ABSORPTION; STEARIC ACIDS; VEHICLES;

EID: 34447635711     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.04.004     Document Type: Article

References (53)

1. Aungst B.J. Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants. J. Pharm. Sci. 6 (1989) 244-247
2. Aungst B.J., Blake J.A., and Hussain M.A. Contributions of drug solubilization, partitioning, barrier disruption and solvent permeation to the enhancement of skin permeation of various compounds with fatty acids and amines. Pharm. Res. 7 (1990) 712-720
3. Banga A.K., Bose S., and Ghosh T.K. Iontophoresis and electroporation: Comparisons and contrasts. Int. J. Pharm. 179 (1999) 1-19
4. Bannon, Y.B., 1989. Ph.D. Thesis. University of Dublin.
5. Barry B.W. Proceed 13th Proceed Intern. Symp. Control. Rel. Bioact. Mater. CRS Inc., IL, USA (1986)
6. Barry B.W. Mode of action of penetration enhancers in human skin. J. Control. Rel. 6 (1987) 85-97
7. Behl C.R., Kumar S., Malick A.W., Del Terzo S., Higuchi W.I., and Nash R.A. Iontophoretic drug delivery: Effects of physicochemical factors on the skin uptake of nonpeptide drugs. J. Pharm. Sci. 78 (1989) 355-360
8. Bommannan D., Potts R.O., and Guy R.H. Examination of the effects of ethanol on human stratum corneum in vivo using infrared spectroscopy. J. Control. Rel. 16 (1991) 299-304
9. Bronaugh R.L., Stewart R.F., and Congdon E.R. Methods for in-vitro percutaneous absorption studies II. Animal models for human skin. Toxicol. Appl. Pharmacol. 62 (1982) 481-487
10. + pemeability of excised nude mouse skin. J. Pharm. Sci. 77 (1988) 492-497
11. Burnette R.R., and Marrero D. Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised mouse skin. J. Pharm. Sci. 75 (1986) 738-743
12. Burnette R.R., and Ongpipattanakul B. Characterization of the permselective properties of excised human skin during iontophoresis. J. Pharm. Sci. 76 (1987) 765-773
13. Carr, M.G., 1992. M.Sc. Thesis. University of Dublin.
14. Carr M.G., Corish J., and Corrigan O.I. Drug delivery from a liquid crystalline base across visking and human stratum corneum. Int. J. Pharm. 157 (1997) 35-42
15. Choi E.H., Lee S.H., Ahn S.K., and Hwang S.M. The pretreatment effect of chemical skin penetration enhancers in transdermal drug delivery using iontophoresis. Skin Pharmacol. Appl. Skin Phys. 12 (1999) 326-335
16. Cooper E.R. Increased skin permeability for lipophilic molecules. J. Pharm. Sci. 73 (1984) 1153-1158
17. De Nuzzio J., and Berner B. Electrochemical and iontophoretic studies of human skin. J. Control. Rel. 11 (1990) 105-122
18. Durrheim H., Flynn G.L., Higuchi W.I., and Behl C.R. Permeation of hairless mouse skin I: experimental methods and comparison with epidermal permeation by alkanols. J. Pharm. Sci. 69 (1980) 781-786
19. Fang J.-Y., Hwang T.L., and Leu Y.-L. Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels. Int. J. Pharm. 250 (2003) 313-325
20. Femenía-Font A., Balaguer-Fernandez C., Merino V., Rodilla V., and Lopez-Castellano A. Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate. Eur. J. Pharm. Biopharm. 61 (2005) 50-55
21. Flynn G.L., Yalkowsky S.H., and Roseman T.J. Mass transport phenomena and models: theoretical concepts. J. Pharm. Sci. 63 (1974) 479-510
22. Fini A., Fazio G., Gonzalez-Rodriguez M., Cavallari C., Passerini N., and Rodriguez L. Formation of ion-pairs in aqueous solutions of diclonefac salts. Int. J. Pharm. 187 (1999) 163-173
23. Francoeur M.L., Golden G.M., and Russell O.P. Oleic acid: its effects on skin in relation to transdermal drug delivery. Pharm. Res. 7 (1990) 621-628
24. Gay C.L., Green P.G., Guy R.H., and Francoeur M.L. Iontophoretic delivery of piroxicam across the skin in vitro. J. Control. Rel. 22 (1992) 57-67
25. Goa S., and Singh J. Effect of oleic acid/ethanol and oleic acid/propylene glycol on the in vitro percutaneous absorption of 5-fluorouracil and tamoxifen and the macroscopic barrier property of porcine epidermis. Int. J. Pharm. 165 (1998) 45-55
26. Golden G.M., Guzek D.B., Kennedy A.H., McKie J.E., and Potts R.O. Stratum corneum lipid phase transitions and water barrier properties. Biochemistry 26 (1987) 2382-2388
27. Gokhale R., Schmidt C., Alcorn L., Stolzenbach J., Schoenhard G., Farhadieh B., and Needham T. Transdermal drug delivery systems of albuterol: In vitro and in vivo studies. J. Pharm. Sci. 81 (1992) 996-1000
28. Goodman M., and Barry B.W. Lipid-protein-partitioning (LPP) theory of skin enhancer activity: finite dose technique. Int. J. Pharm. 57 (1989) 29-40
29. Green P.G., Guy R.H., and Hadgraft J. In vitro and in vivo enhancement of skin permeation with oleic acid and lauric acids. Int. J. Pharm. 48 (1988) 103-111
30. Green P.G., and Hadgraft J. Facilitated transfer of cationic drugs across a lipoidal membrane by oleic-acid and lauric acid. Int. J. Pharm. 37 (1987) 251-255
31. Green P.G., Hadgraft J., and Ridout G. Enhanced in vitro skin permeation of cationic drugs. Pharm. Res. 6 (1989) 628-633
32. Higo N., Naik A., Bommannan D.M., Potts R.O., and Guy R.H. Validation of reflectance IR spectroscopy as a quantitative method to measure percutaneous absorption in vivo. Pharm. Res. 10 (1993) 1500-1506
33. Kalia Y.N., and Guy R.H. Interaction between penetration enhancers and iontophoresis: effect of human skin in vivo. J. Control. Rel. 44 (1997) 33-42
34. Kasting G.B., and Bowman L.A. Electrical analysis of fresh, excised human skin: A comparison with frozen skin. Pharm. Res. 7 (1990) 1141-1146
35. Kligman A.M., and Christophers E. Preparation of isolated sheets of human stratum corneum. Arch. Dermatol. 88 (1963) 702-705
36. Knutson K., Krill S.L., and Zhang J. Solvent-mediated alterations of the stratum corneum. J. Control. Rel. 11 (1990) 93-103
37. Mak V.H., Potts R.O., and Guy R.H. Oleic acid concentration and effect in human stratum corneum: non-invasive determination by attenuated total reflectance infrared spectroscopy in vivo. J. Control. Rel. 12 (1990) 67-75
38. Nolan L.M.A., Corish J., and Corrigan O.I. Electrical properties of human stratum corneum and transdermal drug delivery. J. Chem. Soc. Faraday Trans. 89 (1993) 2839-2845
39. Nolan L.M.A., Corish J., Corrigan O.I., and Fitzpatrick D. Iontophoretic and chemical enhancement of drug delivery part I: Across artificial membranes. Int. J. Pharm. 257 (2003) 41-55
40. Oakley D.A., and Swarbrick J. Effects of ionization on the percutaneous absorption of drugs: Partitioning of nicotine into organic liquids and hydrated stratum corneum. J. Pharm. Sci. 76 (1987) 866-871
41. Oh H.-J., Oh Y.-K., and Kim C.-K. Effects of vehicles and enhancers on transdermal delivery of melatonin. Int. J. Pharm. 212 (2001) 63-71
42. Padmanabhan, R.V., Surnam, J.M., 1991. Patent Corporation Treaty, WO 91/16077, A61K 74/21.
43. Pikal M.J., and Shah S. Transport mechanisms in iontophoresis. III. An experimental study of the contributions of electroosmotic flow and permeability change in transport of low and high molecular weight solutes. Pharm. Res. 7 (1990) 222-229
44. Potts R.O., Golden G.M., Francoeur M.L., Mak V.H.W., and Guy R.H. Mechanism and enhancement of solute transport across the stratum corneum. J. Control. Rel. 15 (1991) 249-260
45. Roberts M.E., and Mueller K.R. Comparisons of in vitro nitroglycerin (TNG) flux across yacatan pig, hairless mouse, and human skins. Pharm. Res. 7 (1990) 673-676
46. Sims S.M., Higuchi W.I., and Srinivasan V. Skin alteration and convective solvent flow effects during iontophoresis: I. Neutral solid transport across human skin. Int. J. Pharm. 69 (1991) 109-121
47. Sims S.M., Higuchi W.I., and Srinivasan V. Skin alteration and convective solvent flow effects during iontophoresis 2. Monovalent anion and cation transport across human skin. Pharm. Res. 9 (1992) 1402-1409
48. Srinivasan V., Higuchi W.I., Sims S.M., Ghanem A.H., and Behl C.R. Transdermal iontophoretic drug delivery: mechanistic analysis and application to polypeptide delivery. J. Pharm. Sci. 5 (1989) 370-375
49. Srinivasan V., Higuchi W.I., and Su M.H. Baseline studies with the four-electrode system: the effect of skin permeability increase and water transport on the flux of a model uncharged solute during iontophoresis. J. Control. Rel. 10 (1989) 157-165
50. Stoughton R.B. In: Maibach H.I. (Ed). Animal Models For In Vitro Percutaneous Absorption (1975), Chruchill Livingstone, New York p. 121
51. Su M.H., Srinivasan V., Ghanem A.H., and Higuchi W.I. Quantitative in vivo iontophoretic studies. J. Pharm. Sci. 83 (1994) 12-17
52. Wang M.Y., Yang Y.Y., and Heng P.W.S. Skin permeation of physostigmine from fatty acids-based formulations: evaluating the choice of solvent. Int. J. Pharm. 290 (2005) 25-36
53. Wang M.Y., Yang Y.Y., and Heng P.W.S. Role of solvent in interactions between fatty acids-based formulations and lipids in porcine stratum corneum. J. Control. Rel. 94 (2004) 207-216