Antileukotrienic N-arylethyl-2-arylacetamides in the treatment of ulcerative colitis

European Journal of Medicinal Chemistry

Volumn 42, Issue 8, 2007, Pages 1084-1094

  Junek, Richard ^a   Brůnová, Bohumila ^a   Kverka, Miloslav ^b   Panajotová, Vladimíra ^c   Jandera, Antonín ^c   Kuchař, Miroslav ^a  

^a Zentiva Prague   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c REaD VUFB Ltd   (Czech Republic)

Author keywords

Antileukotrienic activity; Lipophilicity; N Phenethyl 2 arylacetamides; QSAR; Regression analysis; Treatment of ulcerative colitis

Indexed keywords

ACETAMIDE DERIVATIVE; ARYLACETIC ACID DERIVATIVE; LEUKOTRIENE B4; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; SALAZOSULFAPYRIDINE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING SITE; BIOSYNTHESIS; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HYDROPHOBICITY; LIPOPHILICITY; MACROMOLECULE; MOLECULAR INTERACTION; NONHUMAN; PAW EDEMA; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; ULCERATIVE COLITIS;

ACETAMIDES; ANIMALS; COLITIS, ULCERATIVE; DISEASE MODELS, ANIMAL; EDEMA; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LEUKOTRIENE B4; NEUTROPHILS; RATS; RECEPTORS, LEUKOTRIENE B4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34447631895     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.01.014     Document Type: Article

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