Original Research Papers Effect of manoalide on human 5-lipoxygenase activity

Inflammation Research

Volumn 45, Issue 5, 1996, Pages 218-223

  Cabre F ^a   Carabaza, A ^a   Suesa, N ^a   Garcia A M ^a   Rotllan, E ^a   Gomez M ^a   Tost, D ^a   Mauleon D ^a   Carganico, G ^a,b  

^a Laboratorios Menarini SA   (Spain)

^b Menarini Ricerche SpA   (Italy)

Author keywords

5 lipoxygenase; Eicosanoids; Human leukocytes; Inflammation; Manoalide

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CALCIMYCIN; ICOSANOID; LEUKOTRIENE B4; MANOALIDE; PHOSPHOLIPASE A2; THROMBOXANE B2;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL;

ARACHIDONATE 5-LIPOXYGENASE; CALCIMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IONOPHORES; LEUKOTRIENE B4; NEUTROPHILS; TERPENES; THROMBOXANE B2;

EID: 0029937137     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02259606     Document Type: Article

References (29)

1. De Silva ED, Scheuer PJ. Manoalide, an antibiotic sesterterpenoid from the marine sponge Luffariella variabilis. Tetrahedron Lett 1980;21:1611-4.
2. Burley ES, Smith B, Cutter G, Ahlem JK, Jacobs RS. Antagonism of phorbol 12-myristate 13-acetate (PMA) induced inflammation by the marine natural product, manoalide. Pharmacologist 1982;24:117.
3. Jacobs RS, Culver P, Langdon R, O'Brien T, White S. Some pharmacological observations on marine natural products. Tetrahedron 1981;41:981-4.
4. 2. Biochem Pharmacol 1986;35:449-53.
5. 2. inhibition by manoalide. J Biol Chem 1985;260:7234-40.
6. 2 by manoalide and manoalide analogues. Biochim Biophys Acta 1987;917: 258-68.
7. 2 by manoalide. A model based on the reactivity of manoalide with amino acids and peptide sequences. Biochem Pharmacol 1987;36:2079-86.
8. 2 by the marine natural product, manoalide. Biochem Pharmacol 1990;39: 1557-64.
9. 2 by manoalide and manoanalogue. J Biol Chem 1991;266:16512-7.
10. Bennett CF, Mong S, Clarke MA, Kruse CI, Crooke ST. Differential effects of manoalide on secreted and intracellular phospholipases. Biochem Pharmacol 1987;36:733-40.
11. De Vries GW, Amdahl L, Mobasser A, Wenzel M, Wheeler LA. Preferential inhibition of 5-lipoxygenase activity by manoalide. Biochem Pharmacol 1988;37:2899-905.
12. 2. Agents Actions 1991;34:106-9.
13. Mayer AMS, Glaser KB, Jacobs RS. Regulation of eicosanoid biosynthesis in vitro and in vivo by the marine natural product manoalide: a potent inactivator of venom phospholipases. J Pharm Exp Ther 1988;244:871-8.
14. Tateson JE, Randall RW, Reynolds CH, Jackson WP, Bhattacherjee P, Salmon JA, et al. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: Biochemical assessment in vitro and ex vivo. Br J Pharmacol 1988;94:528-39.
15. 2. Biochim Biophys Acta 1992; 1124:297-9.
16. 2. Biochem Pharmacol 1992;44:519-25.
17. 2 purified from human herniated disc. Biochem Pharmacol 1993;45:783-6.
18. Ford-Hutchinson AW. Regulation of the production and action of leukotrienes by MK-571 and MK-886. In: Samuelsson, et al, editors. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 2nd vol. New York: Raven Press, 1990: 9-16.
19. Guindon Y, Girard Y, Maycock A, Ford-Hutchinson AW, Atkinson JG, Bélanger PC, et al. L-651,392: a novel potent and selective 5-lipoxygenase inhibitor. In: Samuelsson B, Paoletti R, Ranwell PW, editors. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 17th vol. New York: Raven Press, 1987:554-7.
20. 2. J Rheumatol 1991;18:59-65.
21. Crawley GC, Dowell RI, Edwards PN, Foster SJ, McMillan RM, Walker EH, et al. Methoxytetrahydropyrans A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem 1992;35:2600-9.
22. McMillan RM, Spruce KE, Crawley GC, Walker EHR, Foster SJ. Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase. Br J Pharmacol 1992;107:1042-7.
23. Gillard J, Ford-Hutchinson AW, Chan C, Charleson S, Denis D, Foster A, et al. L-663,536 (MK-886), a novel, orally active leukotriene biosynthesis inhibitor. Can J Physiol Pharmacol 1989;67:456-64.
24. Dannhardt G, Lehr M. In vitro evaluation of 5-lipoxygenase and cyclo-oxygenase inhibitors using bovine neutrophils and platelets and HPLC. J Pharm Pharmacol 1992;44:419-24.
25. 2 by the marine natural products manoalide, Luffariellolide and Scalaradial. J Am Chem Soc 1992;114:5093-100.
26. 2 with manoalide. J Med Chem 1993;36:1866-79.
27. Jacobson PB, Schrier DJ. Regulation of CD11b/CD18 expression in human neutrophils by phospholipase A. J Immunol 1993;151:5639-52.
28. Voss C, Sepulveda-Boza S, Zilliken FW. New isoflavonoids as inhibitors of porcine 5-lipoxygenase. Biochem Pharmacol 1992;44:157-62.
29. Riendeau D, Falgueyret JP, Nathaniel DJ, Rokach J. Sensitivity of immunoaffinity-purified procine 5-lipoxygenase to inhibitors and activating lipid hydroperoxides. Biochem Pharmacol 1989;38:2313-21.