Thromboxane A2 receptor-mediated cell proliferation, survival and gene expression in oligodendrocytes

Journal of Neurochemistry

Volumn 93, Issue 2, 2005, Pages 257-268

  Lin, Xin ^a   Ramamurthy, Santosh K ^a   Le Breton, Guy C ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

CREB; ERK1 2; Oligodendrocyte; Proliferation; Survival; Thromboxane A 2 receptor

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; THROMBOXANE A2 RECEPTOR;

ANALYSIS OF VARIANCE; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELL TYPE; CELL VIABILITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STAINING; STEM CELL; STIMULATION; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2;

EID: 17444422791     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02969.x     Document Type: Article

References (64)

1. Abad B., Mesonero J. E., Salvador M. T., Garcia-Herrera J. and Rodriguez-Yoldi M. J. (2002) Cellular mechanism uderlying LPS-induced inhibition of in vitro 1-leucine transport across rabbit jejunum. Endotoxin Res. 8, 127-133.
2. Ali S., Davis M. G., Backer M. W. and Dorn G. M. (1993) Thromboxane A2 stimulates vascular smooth muscle hypertrophy by up-regulating the synthesis and release of endogenous basic fibroblast growth factor. J. Biol. Chem. 268, 17 397-17 403.
3. Asotra K. and Macklin W. B. (1994) Developmental expression of protein kinase C isozymes in oligodendrocytes and their differential modulation by 4β-phorbol-12,13-dibutyrate. J. Neurosci. Res. 39, 273-289.
4. Baron W., MetZ. B., Bansal R., Hoekstra D. and de Vries H. (2000) PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathway. Mol. Cell Neurosci. 15, 314-329.
5. Barres B. A., Hart I. K., Coles H. S., Burne J. F., Voyvodic J. T., Richardson W. D. and Raff M. C. (1992) Cell death control of cell survival in the oligodendrocyte lineage. Cell 70, 31-46.
6. Bhat N. R., Hauser K. F. and Kindy M. S. (1992) Cell proliferation and protooncogene induction in oligodendroglial progenitors. J. Neurosci. Res. 32, 340-349.
7. Blackman S. C., Dawson G., Antonakis K. and Le Breton G. C. (1998) The identification and characterization of oligodendrocyte thromboxane A2 receptors. J. Biol. Chem. 273, 475-483.
8. Bonni A., Brunet A., West A. E., Datta S. R., Takasu M. A. and Greenberg M. E. (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and - independent mechanisms. Science 286, 1358-1362.
9. Borg C., Lim C. T., Yeomans D. C., Dieter J. P., Komiotis D., Anderson E. G. and LeBreton G. C. (1994) Purification of rat brain, rabbit aorta, and human platelet thromboxane A2/prostaglandin H2 receptors by immunoaffinity chromatography employing antipeptide and anti-receptor antibodies. J. Biol. Chem. 269, 6109-6116.
10. Boulom V., Lee H. W., Zhao L. and Eghbali-Webb M. (2002) Stimulation of DNA synthesis, activation of mitogen-activated protein kinase ERK2 and nuclear accumulation of c-fos in human aortic smooth muscle cells by ketamine. Cell Prolif. 35, 155-165.
11. Chen J. and Iyengar R. (1994) Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s. Science 263, 1278-1281.
12. Cohen R. I., Molina-Holgado E. and Almazan G. (1996) Carbachol stimulates c-fos expression and proliferation in oligodendrocyte progenitors. Mol. Brain Res. 43, 193-201.
13. D'Angelo G., Lee H. and Weiner R. I. (1997) cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation. J. Cell. Biochem. 67, 353-366.
14. Djellas Y., Manganello J. M., Antonakis K. and LeBreton G. C. (1999) Identification of Galpha13 as one of the G-porteins that couple to human platelet thromboxane A2 receptors. J. Biol. Chem. 274, 14 325-14 330.
15. Gao Y. L., Tang S., Zhou S. and Ware J. A. (2001) The thromboxane A2 receptor activates mitogen-activated protein kinase via protein kinase C-dependent Gi coupling and Src- dependent phosphorylation of the epidermal growth factor receptor. J. Pharmacol. Exp. Ther. 296, 426-433.
16. Gao Y., Yokota R., Tang S., Ashton A. W. and Ware J. A. (2000) Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A (2). Circ Res. 87, 739-745.
17. Gilmore S. A. (1971) Neuroglial population in the spinal white matter of neonatal and early postnatal rats: an autoradiographic study of numbers of neuroglia and changes in their proliferative activity. Anat. Rec. 171, 283-291.
18. Ginty D. D., Bonni A. and Greenberg M. E. (1994) Nerve growth factor activates a Ras- dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77, 713-725.
19. Gonzalez. G. A., Yamamoto K. K., Fischer W. H., Karr D., Menzel P., Biggs W. I., Vale W. W. and Montminy M. R. (1989) A cluster of phosphorylation sites on the cyclic cAMP-regulated nuclear factor CREB predicted by its sequence. Nature 337, 749-752.
20. Gutkind J. S. (1998) The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J. Biol. Chem. 273, 1839-1842.
21. Heinrich M., Gorath M. and Richter-Landsberg C. (1999) Neurotrophin-3 (NT-3) modulates early differentiation of oligodendrocytes in rat brain cortical cultures. Glia 28, 244-255.
22. Hirata M., Hayashi Y., Ushikubi F., Yokota Y., Kageyama R., Nakanishi S. and Narumiya S. (1991) Cloning and expression of cDNA for a human thromboxane A2 receptor. Nature 349, 617-620.
23. Jiang F., Frederick T. J. and Wood T. L. (2001) IGF-1 synergizes with FGF-2 to stimulate oligodendrocyte progenitor entry into cell cycle. Dev. Biol. 232, 414-423.
24. Johnson J. R., Chu A. K. and Sato-Bigbee C. (2000) Possible role of CREB in the stimulation of oligodendrocyie precursor cell proliferation by neurotrophin-3. J. Neurochem. 74, 1409-1417.
25. Jones D. A., Benjamin C. W. and Linseman D. A. (1995) Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades. Mol. Pharmacol. 48, 890-896.
26. Kanashiro C. A. and Khalil R. A. (1998) Signal transduction by protein kinase C in mammalian cells. Clin. Exp. Pharmacol. Physiol. 25, 974-985.
27. Khorchid A., Larocca J. N. and Almazan G. (1999) Characterization of the signal transduction pathways mediating noradrenline-stimulated MAPK activation and c-fos expression in oligodendrocyte progenitors. J. Neurosci. Res. 58, 765-778.
28. Knezevic I., Borg C. and Le Breton G. C. (1993) Identification of Gq as one of G-proteins which copurify with human platelet thromboxane A2/prostaglandin H2 receptors. J. Biol. Chem. 268, 26 011-26 017.
29. Kurada P. and White K. (1998) Ras promotes cell survival in Drosophila by downregulating hid expression. Cell 95, 319-329.
30. Kürzel F., Hagel Ch, Zapf S., Heissner H., Westphal M. and Giese A. (2002) Cyclo-oxygenase inhibitors and thromboxane synthase inhibitors differentially regulate migration arrest, growth inhibition and apoptosis in human glioma cells. Acta Neurochir (Wen) 144, 71-87.
31. Louis J. C., Magal E., Muir D., Manthorpe M. and Varon S. (1992) CG4, A new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes. J. Neurosci. Res. 31, 193-204.
32. Louis J. C., Magal E., Takayama S. and Varon S. (1993) CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death. Science 259, 689-692.
33. McCarthy K. D. and de Vellis J. (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 85, 890-902.
34. McMorris F. A. and Dubios-Dalcq M. (1988) Insulin-like growth factor-I promotes cell proliferation and oligodendroglia commitment in rat glia progenitor cells developing in vitro. J. Neurosci. Res. 21, 199-209.
35. Meier P. and Evan G. (1998) Dying likes flies. Cell 95, 295-298.
36. Miggin S. M. and Kinsella B. T. (2001) Thromboxane A2 receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells. Biochim. Et Biophys. Acta 1539, 147-162.
37. Miggin S. M. and Kinsella B. T. (2002) Regulation of extracellular signal-regulated kinase cascades by α- and β-isoforms of the human thromboxane A2 receptor. Mol. Pharmacol. 61, 817-831.
38. Miller R. H. (1996) Oligodendrocyte origins. Trends Neurosci. 19, 92-96.
39. Miller R. H., Payne J., Milner L., Zhang H. and Orentas D. M. (1997) Spinal cord oligodendrocytes develop from a limited number of migratory highly proliferative precursors. J. Neurosci. Res. 50, 157-168.
40. Morinelli T. A., Zhang L. M., Newman W. H. and Meier K. E. (1994) Thromboxane A2/prostaglandin H2-stimulated mitogenesis of coronary artery smooth muscle cells involves activation of mitogen-activated protein kinase and S6 kinase. J. Biol. Chem. 269, 5693-5698.
41. Muja N., Blackman S. C., LeBreton G. C. and DeVries G. H. (2001) Identification and functional characterization of thromboxane A2 receptors in Schwann cells. J. Neurochem. 78, 446-456.
42. Musashi M., Ota S. and Shiroshita N. (2000) The role of protein kinase C isoforms in cell proliferation and apoptosis. Int. J. Hematol. 72, 12-19.
43. Nigam S., Eskafi S., Roscher A. and Weitzel H. (1993) Thromboxane A2 analogue U46619 enhances tumour cell proliferaiton HeLa cells via specific receptor which are apparently distinct from TXA2 receptors on human platelets. FEBS Lett. 316, 99-102.
44. Noll E. and Miller R. H. (1993) Oligodendrocyte precursors originate at the ventral ventricular zone dorsal to the ventral midline region in the embryonic rat spinal cord. Development 118, 563-573.
45. Offermanns S., LaugwitZ. K. L., Spicher K. and SchultZ. G. (1994) G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proceedings Natl. Acad. Sci. USA 91, 504-508.
46. Pringle N. P., Mudhar H. S., Collarini E. J. and Richardson W. D. (1992) PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha receptor expression appears to be restricted to glial cells of the Oligodendrocyte lineage. Development 115, 535-551.
47. Ragheb F., Molina-Holgado E., Cui Q. L., Khorchid A., Liu H. N., Larocca J. N. and Almazan G. (2001) Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes. J. Neurochem. 77, 1396-1406.
48. Sachinidis A., Flesch M., Ko Y., Schror K., Bohm M., Dusing R. and Vetter H. (1995) Thromboxane A2 and vascular smooth muscle cell proliferation. Hypertension 26, 771-780.
49. Salvi M., Brunati A. M., Bordin L., Rocca N. L., Clari G. and Tonindlo A. (2002) Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria. Biochim. Et Biophys. Acta 1589, 181-192.
50. Shenker A., Goldsmith P., Unson C. G. and Spiegel A. M. (1991) The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. J. Biol. Chem. 266, 9309-9313.
51. Shizukuda Y. and Buttrick P. M. (2002) Protein kinase C-zeta modulates thromboxane A (2)-mediated apoptosis in adult ventricular myocytes via Akt. Am. J. Physiol. Heart Circ. Physiol. 82, H320-H327.
52. Ushikubi F., Aiba Y., Nakamura K., Namba T., Hirata M., Mazda O., Katsura Y. and Narumiya S. (1993) Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis. J. Exp. Med. 178, 1825-1830.
53. Ushikubi F., Nakamura K. and Narumiya S. (1994) Functional reconstitution of platelet thromboxane A2 receptors with Gq and Gi2 in phospholipid vesicles. Mol. Pharmacol. 46, 808-816.
54. Vezza R., Habib A. and FitzGerald G. A. (1999) Differential signaling by the thromboxane receptor isoforms via the novel GTP-binding protein, Gh. J. Biol. Chem. 274, 12 774-12 779.
55. Vollgraf U., Wegner M. and Richter-Landsberg C. (1999) Activation of AP-1 and nuclear factor-kB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes. J. Neurochem. 73, 2501-2509.
56. Warf B. C., Fok Seang J. and Miller R. H. (1991) Evidence for the ventral origin of Oligodendrocyte precursors in the rat spinal cord. J. Neurosci. 11, 2477-2488.
57. Warrington A. E., Barbarese E. and Pfeiffer S. E. (1993) Differential myelinogenic capacity of specific developmental stages of the Oligodendrocyte lineage upon transplantation into hypomyelinating hosts. J. Neurosci. Res. 34, 1-13.
58. Xia Z., Dickens M., Raingeaud J., Davids R. J. and Greenberg M. E. (1995) Opposing effects of ERK and JNK-p38 MAP kinase on apoptosis. Science 270, 1326-1331.
59. Xie H. and Rothstein T. L. (1995) Protein kinase C mediates activation of nuclear cAMP response element binding protein (CREB) in lymphocytes stimulated through surface Ig. J. Immunol. 154, 1717-1723.
60. Xing J., Ginty D. D. and Greenberg M. E. (1996) Coupling of the Ras-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273, 959-963.
61. Yamamoto K. K., Gonzalez. G. A., Biggs W. H. III and Montminy M. R. (1988) Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334, 494-498.
62. + oligodendrocyte-lineage cells and increases oligodendrocyte myelination in vitro. J. Neurosci. Res. 62, 329-335.
63. Zhang C. Y., Wu Y. L. and Boxer L. M. (2002) Impaired proliferation and survival of activated B cells in transgenic mice expressing a dominant-negative CREB transcription factor in B cells. J. Biol. Chem. 277, 48 359-48 365.
64. Zhao Y. J. and Foegh M. L. (1997) Angiopeptin, a Somatostatin Analogue, inhibits rat coronary artery and aorta smooth muscle cell proliferation induced by the thromboxane A2 mimetic U46619. Prostaglandins 54, 781-793.