Autonomic cardiovascular and respiratory control during prolonged spaceflights aboard the International Space Station

Journal of Applied Physiology

Volumn 103, Issue 1, 2007, Pages 156-161

  Baevsky, Roman M ^a   Baranov, Victor M ^a   Funtova, Irina I ^a   Diedrich, André ^c   Pashenko, Andrey V ^a   Chernikova, Anja G ^a   Drescher, Jürgen ^d   Jordan, Jens ^b   Tank, Jens ^b,e  

^a INSTITUTE OF BIOMEDICAL PROBLEMS   (Russian Federation)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GERMAN AEROSPACE CENTER DLR   (Germany)

^e FRANZ VOLHARD CLINIC   (Germany)

Author keywords

Autonomic nervous system; Cardiovascular physiology; Heart rate variability; Microgravity; Spaceflight

Indexed keywords

ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD SMEAR; BODY MASS; BREATHING RATE; CARDIOVASCULAR FUNCTION; CHOLINERGIC SYSTEM; COSMONAUT; ELECTROCARDIOGRAPHY; HEART OUTPUT; HEART RATE; HEART RATE VARIABILITY; HUMAN; MALE; MICROGRAVITY; NORMAL HUMAN; PHOTOELECTRIC PLETHYSMOGRAPHY; PRIORITY JOURNAL; PULSE WAVE; RESPIRATION CONTROL; SPACE FLIGHT;

ADULT; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; ELECTROCARDIOGRAPHY; EUROPE; HEART RATE; HUMANS; HYPOTENSION, ORTHOSTATIC; INTERNATIONAL COOPERATION; MALE; MIDDLE AGED; PHOTOPLETHYSMOGRAPHY; POSTURE; RESPIRATORY FUNCTION TESTS; RESPIRATORY MECHANICS; RESPIRATORY SYSTEM; SPACE FLIGHT; TIME FACTORS; UNITED STATES; WEIGHTLESSNESS;

EID: 34447627941     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00137.2007     Document Type: Article

References (43)

1. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J 17: 354-81, 1996.
2. Ali YS, Daamen N, Jacob G, Jordan J, Shannon JR, Biaggioni I, Robertson D. Orthostatic intolerance: a disorder of young women. Obstet Gynecol Surv 55: 251-259, 2000.
3. Atkov OY, Bednenko VS, Fomina GA. Ultrasound techniques in space medicine. Aviat Space Environ Med 58: A69-A73, 1987.
4. Baevsky RM. [Analysis of variability of cardiac rhythm in space medicine.] Fiziol Cheloveka 28: 70-82, 2002.
5. Buckey JC Jr, Gaffney FA, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Yancy CW Jr, Meyer DM, Blomqvist CG. Central venous pressure in space. J Appl Physiol 81: 19-25, 1996.
6. Buckey JC Jr, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Moore WE, Gaffney FA, Blomqvist CG. Orthostatic intolerance after spaceflight. J Appl Physiol 81: 7-18, 1996.
7. Christensen NJ, Heer M, Ivanova K, Norsk P. Sympathetic nervous activity decreases during head-down bed rest but not during microgravity. J Appl Physiol 99: 1552-1557, 2005.
8. Convertino VA, Cooke WH. Evaluation of cardiovascular risks of spaceflight does not support the NASA bioastronautics critical path roadmap. Aviat Space Environ Med 76: 869-876, 2005.
9. Convertino VA, Ludwig DA, Elliott JJ, Wade CE. Is there resetting of central venous pressure in microgravity? J Gravit Physiol 8: 51-52, 2001.
10. Cooke WH, Ames JE, IV, Crossman AA, Cox JF, Kuusela TA, Tahvanainen KU, Moon LB, Drescher J, Baisch FJ, Mano T, Levine BD, Blomqvist CG, Eckberg DL. Nine months in space: effects on human autonomic cardiovascular regulation. J Appl Physiol 89: 1039-1045, 2000.
11. Cooke WH, Cox JF, Diedrich AM, Taylor JA, Beightol LA, Ames JE, Hoag JB, Seidel H, Eckberg DL. Controlled breathing protocols probe human autonomic cardiovascular rhythms. Am J Physiol Heart Circ Physiol 274: H709-H718, 1998.
12. Cox JF, Tahvanainen KU, Kuusela TA, Levine BD, Cooke WH, Mano T, Iwase S, Saito M, Sugiyama Y, Ertl AC, Biaggioni I, Diedrich A, Robertson RM, Zuckerman JH, Lane LD, Ray CA, White RJ, Pawelczyk JA, Buckey JC Jr, Baisch FJ, Blomqvist CG, Robertson D, Eckberg DL. Influence of microgravity on astronauts' sympathetic and vagal responses to Valsalva's manoeuvre. J Physiol 538: 309-320, 2002.
13. Eckberg DL. Sympathovagal balance: a critical appraisal. Circulation 96: 3224-3232, 1997.
14. Eckberg DL. Bursting into space: alterations of sympathetic control by space travel. Acta Physiol Scand 177: 299-311, 2003.
15. Eckberg DL, Fritsch JM. Human autonomic responses to actual and simulated weightlessness. J Clin Pharmacol 31: 951-955, 1991.
16. Elliott AR, Prisk GK, Guy HJ, West JB. Lung volumes during sustained microgravity on Spacelab SLS-1. J Appl Physiol 77: 2005-2014, 1994.
17. Ertl AC, Diedrich A, Biaggioni I, Levine BD, Robertson RM, Cox JF, Zuckerman JH, Pawelczyk JA, Ray CA, Buckey JC Jr, Lane LD, Shiavi R, Gaffney FA, Costa F, Holt C, Blomqvist CG, Eckberg DL, Baisch FJ, Robertson D. Human muscle sympathetic nerve activity and plasma noradrenaline kinetics in space. J Physiol 538: 321-329, 2002.
18. Fritsch-Yelle JM, Charles JB, Jones MM, Wood ML. Microgravity decreases heart rate and arterial pressure in humans. J Appl Physiol 80: 910-914, 1996.
19. Goldberger AL, Bungo MW, Baevsky RM, Bennett BS, Rigney DR, Mietus JE, Nikulina GA, Charles JB. Heart rate dynamics during long-term space flight: report on Mir cosmonauts. Am Heart J 128: 202-204, 1994.
20. Greenleaf JE. Physiology of fluid and electrolyte responses during inactivity: water immersion and bed rest. Med Sci Sports Exerc 16: 20-25, 1984.
21. Gundel A, Drescher J, Spatenko YA, Polyakov VV. Heart period and heart period variability during sleep on the MIR space station. J Sleep Res 8: 37-43, 1999.
22. Hargens AR, Watenpaugh DE. Cardiovascular adaptation to spaceflight. Med Sci Sports Exerc 28: 977-982, 1996.
23. Hirsch JA, Bishop B. Respiratory sinus arrhythmia in humans: how breathing pattern modulates heart rate. Am J Physiol Heart Circ Physiol 241: H620-H629, 1981.
24. Jennings RT. Managing space motion sickness. J Vestib Res 8: 67-70, 1998.
25. Kozlovskaya IB, Grigoriev AI. Russian system of countermeasures on board of the International Space Station (ISS): the first results. Acta Astronaut 55: 233-237, 2004.
26. Levine BD, Pawelczyk JA, Ertl AC, Cox JF, Zuckerman JH, Diedrich A, Biaggioni I, Ray CA, Smith ML, Iwase S, Saito M, Sugiyama Y, Mano T, Zhang R, Iwasaki K, Lane LD, Buckey JC Jr, Cooke WH, Baisch FJ, Eckberg DL, Blomqvist CG. Human muscle sympathetic neural and haemodynamic responses to tilt following spaceflight. J Physiol 538: 331-340, 2002.
27. Malliani A, Pagani M, Lombardi F, Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 84: 482-492, 1991.
28. 1-adrenergic receptor responses before flight and central autonomic dysregulation postflight. Am J Physiol Heart Circ Physiol 286: H1486-H1495, 2004.
29. Migeotte PF, Prisk GK, Paiva M. Microgravity alters respiratory sinus arrhythmia and short-term heart rate variability in humans. Am J Physiol Heart Circ Physiol 284: H1995-H2006, 2003.
30. Norsk P, Damgaard M, Petersen L, Gybel M, Pump B, Gabrielsen A, Christensen NJ. Vasorelaxation in space. Hypertension 47: 69-73, 2006.
31. Pagani M, Lombardi F, Guzzetti S, Rimoldi O, Furlan R, Pizzinelli P, Sandrone G, Malfatto G, Dell'Orto S, Piccaluga E. Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog. Circ Res 59: 178-193, 1986.
32. Parin VV, Gazenko OG. Soviet experiments aimed at investigating the influence of space flight factors on the physiology of animals and man. Life Sci Space Res 1: 113-127, 1963.
33. Perhonen MA, Franco F, Lane LD, Buckey JC, Blomqvist CG, Zerwekh JE, Peshock RM, Weatherall PT, Levine BD. Cardiac atrophy after bed rest and spaceflight. J Appl Physiol 91: 645-653, 2001.
34. Prisk GK, Fine JM, Cooper TK, West JB. Vital capacity, respiratory muscle strength, and pulmonary gas exchange during long-duration exposure to microgravity. J Appl Physiol 101: 439-447, 2006.
35. Prisk GK, Guy HJ, Elliott AR, Deutschman RA, III, West JB. Pulmonary diffusing capacity, capillary blood volume, and cardiac output during sustained microgravity. J Appl Physiol 75: 15-26, 1993.
36. Sides MB, Vernikos J, Convertino VA, Stepanek J, Tripp LD, Draeger J, Hargens AR, Kourtidou-Papadeli C, Pavy-LeTraon A, Russomano T, Wong JY, Buccello RR, Lee PH, Nangalia V, Saary MJ. The Bellagio Report. Cardiovascular risks of spaceflight: implications for the future of space travel. Aviat Space Environ Med 76: 877-895, 2005.
37. Smirk FH. Casual, basal and supplemental blood pressures in 519 first-degree relatives of substantial hypertensive patients and in 350 population controls. Clin Sci Mol Med Suppl 3: 13s-17s, 1976.
38. Spaak J, Sundblad P, Linnarsson D. Impaired pressor response after spaceflight and bed rest: evidence for cardiovascular dysfunction. Eur J Appl Physiol 85: 49-55, 2001.
39. 2 Adrenergic transmission and human baroreflex regulation. Hypertension 43: 1035-1041, 2004.
40. Watenpaugh DE, Buckey JC, Lane LD, Gaffney FA, Levine BD, Moore WE, Wright SJ, Blomqvist CG. Effects of spaceflight on human calf hemodynamics. J Appl Physiol 90: 1552-1558, 2001.
41. White RJ, Averner M. Humans in space. Nature 409: 1115-1118, 2001.
42. Zhang LF. Vascular adaptation to microgravity: what have we learned? J Appl Physiol 91: 2415-2430, 2001.
43. Zhang LF. Vascular adaptation to microgravity. J Appl Physiol 97: 1584-1585, 2004.