A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea

Peptides

Volumn 28, Issue 7, 2007, Pages 1331-1343

  Thompson, Alan Hunter ^a   Bjourson, Anthony John ^a   Orr, David Francis ^a   Shaw, Chris ^b   McClean, Stephen ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Amphibian skin secretion; Antimicrobial peptide; cDNA cloning; De novo peptide sequencing; Phyllomedusa hypochondrialis azurea

Indexed keywords

COMPLEMENTARY DNA; DERMASEPTIN; PEPTIDE; PHYLLOSEPTIN; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMPHIBIA; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA LIBRARY; DNA SEQUENCE; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; ESCHERICHIA COLI; FROG; GENOMICS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHYLLOMEDUSA HYPOCHONDRIALIS AZUREA; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEOMICS; QUANTITATIVE ANALYSIS; SKIN SECRETION; STAPHYLOCOCCUS AUREUS; TIME OF FLIGHT MASS SPECTROMETRY;

AMINO ACID SEQUENCE; AMPHIBIAN PROTEINS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANURA; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SKIN;

AMPHIBIA; ESCHERICHIA COLI; MICROCOCCUS LUTEUS; NEGIBACTERIA; PHYLLOMEDUSA HYPOCHONDRIALIS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 34447623002     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.05.001     Document Type: Article

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