Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain

European Journal of Biochemistry

Volumn 270, Issue 9, 2003, Pages 2068-2081

  Vanhoye, Damien ^a   Bruston, Francine ^a   Nicolas, Pierre ^a   Amiche, Mohamed ^a  

^a INSTITUT JACQUES MONOD   (France)

Author keywords

Antimicrobial peptides; Dermaseptin; Frog skin; Gene family; Hypermutation

Indexed keywords

ANTIINFECTIVE AGENT; PEPTIDE;

ACCELERATION; ALPHA HELIX; ARTICLE; AUSTRALIA; BIOGEOGRAPHY; CONTROLLED STUDY; ECOLOGICAL NICHE; FRAGMENTATION REACTION; FROG; MICROORGANISM; MULTIDRUG RESISTANCE; MUTAGENESIS; MUTAGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRECURSOR; PRIORITY JOURNAL; PROBABILITY; SOUTH AMERICA; SPECTRUM;

AMINO ACID SEQUENCE; AMPHIBIAN PROTEINS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANURA; BASE SEQUENCE; CLONING, MOLECULAR; EVOLUTION, MOLECULAR; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN PRECURSORS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

AMPHIBIA; ANURA; ESCHERICHIA COLI; HYLIDAE; REPTILIA;

EID: 0038706380     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03584.x     Document Type: Article

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