Antibiotic properties of novel synthetic temporin A analogs and a cecropin A-temporin a hybrid peptide

Protein and Peptide Letters

Volumn 9, Issue 6, 2002, Pages 533-543

  Wade, David ^a,f   Flock, Jan Ingmar ^a   Edlund, Charlotta ^a   Löfving Arvholm, Ingegerd ^a   Sällberg, Matti ^a   Bergman, Tomas ^a,b   Silveira, Angela ^a   Unson, Cecille ^a,c   Rollins Smith, Louise ^a,d   Silberring, Jerzy ^a,e   Richardson, Malcom ^a,f   Kuusela, Pentti ^a,f,g   Lankinen, Hilkka ^a,f  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ROCKEFELLER UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e JAGIELLONIAN UNIVERSITY   (Poland)

^f UNIVERSITY OF HELSINKI   (Finland)

^g HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Antibiotic peptides; Antibiotic resistant bacteria; Antifungal; Cecropin A; Hemolysis; Human erythrocyte lysis; Ranatuerin 6; Temporin A; VesCP M

Indexed keywords

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOLOGICAL ASSAY; HEMOLYSIS; HUMANS; PEPTIDES; PROTEINS; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

FUNGI;

EID: 0037005352     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929866023408409     Document Type: Article

References (28)

1. Simmaco, M., Mignogna, G. Canofeni, S., Miele, R., Mangoni, M.L., and Barra, D. (1996) Eur. J. Biochem. 242, 788.
2. Wade, D., Silveira, A., Silberring, J., Kuusela, P., and Lankinen, H. (2000) Protein Peptide Letts. 7(6), 349.
3. Wade, D. (2002) Internet J. Chem. 5, 5 (http://www.ijc.com/abstracts/TOC2002).
4. Boman, H.G. (2000) Immunol. Rev. 173, 5.
5. Wade, D., Bergman, T., Silberring, J., and Lankinen, H. (2001) Protein Peptide Letts. 8(6), 443.
6. Wade, D., Silberring, J., Soliymani, R., Heikkinen, S., Lankinen, H., and Kuusela, P. (2000) FEBS Letts. 479 (1-2), 6.
7. Kyte, J., and Doolittle, R.F. (1982) J. Mol. Biol. 157, 105.
8. Hujakka, H., Ratilainen, J., Korjamo, T., Lankinen, H., Kuusela, P., Santa, H., Laatikainen, R. and Närvänen, A. (2001) Bioorg. Med. Chem. 9, 1601.
9. Goraya, J., Knoop, F.C. and Conlon, J.M. (1998) Biochem. Biophys. Res. Commun. 250, 589.
10. Rollins-Smith, L.A., Doersam, J.K., Longcore, J.E., Taylor, S.K., Shamblin, J.C., Carey, C. and Zasloff, M.A. (2002) Dev. Comp. Immunol. 26, 63-72.
11. Oh, H., Hedberg, M., Wade, D., and Edlund, C. (2000) Antimicrob. Agents Chemother. 44, 68.
12. Wade, D., Boman, A., Wåhlin, B., Drain, C.M., Andreu, D., Boman, H.G., and Merrifield, R.B. (1990) Proc. Natl. Acad. Sci. USA 87, 4761.
13. Reynolds, R.C. (2002) TAACF, Southern Research Institute, Birmingham, AL, USA, personal commun.
14. Mangoni, M.L., Rinaldi, A.C, DiGiulio, A., Mignogna, G., Bozzi, A., Barra, D., and Simmaco, M. (2000) Eur. J. Biochem. 267, 1447.
15. Ponti, D., Mignogna, G., Mangoni, M.L., DeBiase, D., Simmaco, M., and Barra, D. (1999) Eur. J. Biochem. 263, 921.
16. 11 erythrocytes (0.8%) per day [17].
17. Pallister, C. (1994) Blood, Physiology and Pathophysiology, p. 11, Butterworth-Heinmann, Oxford.
18. 2).
19. th ed., p. 869, Appleton & Lange, Stamford.
20. th ed., p. 356, W.B. Saunders Company, Philadelphia.
21. Wade, D., Silveira, A., Rollins-Smith, L., Bergman, T., Silberring, J. and Lankinen, H. (2001) Acta Biochim. Polonica 48, 1185.
22. Chu, A., Chen, B.M., Lin, H., and Beydoun, S. (2001) Arch. Biochem Biophys. 392, 3.
23. Kovacs, F., Quine, J., and Cross, T.A. (1999) Proc. Natl. Acad. Sci. USA 96, 7910.
24. Luo, Y., Pfuetzner, R.A., Mosimann, S., Paetzel, M., Frey, E.A., Cherney, M., Kim, B., Little, J.W. and Strynadka, N.C.J. (2001) Cell 106, 585
25. Shoemaker, K.R., Kim, P.S., York, E.J., Stewart, J.M. and Baldwin, R.L. (1987) Nature 326, 563.
26. Vunnam, S., Juvvadi, P., Rotondi, K., and Merrifield, R.B. (1998) J. Peptide Res. 51, 38.
27. Aurora, R., and Rose, G.D. (1998) Protein Sci. 7, 21.
28. Andreu, D., Ubach, J., Boman, A., Wåhlin, B., Wade, D., Merrifield, R.B., and Boman, H.G. (1992) FEBS Lett. 296, 190.