Copper complexing decreases the ability of amyloid beta peptide to cross the BBB and enter brain parenchyma

Peptides

Volumn 28, Issue 7, 2007, Pages 1424-1432

  Mare, Suneetha ^a   Penugonda, Suman ^a   Robinson, Sandra M ^b   Dohgu, Shinya ^b   Banks, William A ^b   Ercal, Nuran ^a  

^a MISSOURI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid beta peptide; BBB; Copper

Indexed keywords

ALUMINUM; AMYLOID BETA PROTEIN; COPPER; CYSTEINE; GLUTATHIONE; HOMOCYSTEINE; METAL ION;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CELL LINE; CELL VIABILITY; CHELATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARENCHYMA; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CELL SURVIVAL; CHELATING AGENTS; COPPER; ENDOTHELIAL CELLS; HUMANS; MICE; MICE, INBRED STRAINS; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; RATS; SULFHYDRYL COMPOUNDS; TIME FACTORS;

RATTUS;

EID: 34447622091     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.05.007     Document Type: Article

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