Stool DNA analysis detects premorphological colorectal neoplasia: A case report

European Journal of Gastroenterology and Hepatology

Volumn 19, Issue 8, 2007, Pages 725-727

  Øgreid, Dagfinn ^a   Hamre, Erik ^b  

^a STAVANGER UNIVERSITY HOSPITAL   (Norway)

^b Volvat Medical Center   (Norway)

Author keywords

Colorectal cancer; Genetic testing in stool; Kras; Premalignant polyp

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CASE REPORT; COLONOSCOPY; COLORECTAL TUMOR; DNA DETERMINATION; ENDOSCOPIC SURGERY; FAMILIAL DISEASE; FECES ANALYSIS; GENE MUTATION; HUMAN; HYPERTENSION; INTESTINE POLYP; MALE; ONCOGENE K RAS; PRIORITY JOURNAL; PROSTATE CANCER;

COLONIC POLYPS; COLORECTAL NEOPLASMS; DNA, NEOPLASM; FECES; GENETIC MARKERS; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASTIC SYNDROMES, HEREDITARY; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 34447580046     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328133f2c1     Document Type: Article

References (18)

1. Levin B, Brooks D, Smith RA, Stone A. Emerging technologies in screening for colorectal cancer: CT colonography, immunochemical fecal occult blood tests, and stool screening using molecular markers. CA Cancer J Clin 2003; 53:44-55.
2. Morson BC. Evolution of cancer of the colon and rectum. Cancer 1974; 34 (Suppl 2974):845-849.
3. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenisis. Cell 1990; 61:759-767.
4. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159-170.
5. Kozuka S, Nogaki M, Ozeki T, Masumori S. Premalignancy of the mucosal polyp in the large intestine: II. Estimation of the periods required for malignant transformation of mucosal polyps. Dis Colon Rectum 1976; 18:494-500.
6. Brien MJ, Winawer SJ, Zauber AG, Gottlieb LS, Sternberg SS, Diaz B, et al. The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology 1990; 98:371-379.
7. Osborn NK, Ahlquist DA. Stool screening for colorectal cancer: molecular approaches. Gastroenterology 2005; 128:192-206.
8. Davies RJ, Miller R, Coleman N. Colorectal cancer screening: prospects for molecular stool analysis. Nat Rev Cancer 2005; 5:199-209.
9. Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, et al. Mutations of chromosome 5q21 in FAP and colorectal cancer patients. Science 1991; 253:665-669.
10. Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DD, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253:661-665.
11. Takayama T, Miyanishi K, Hayashi T, Stao Y, Niitsu YJ. Colorectal cancer: genetics of development and metastasis. Gastroenterology 2006; 41:185-192.
12. Konishi K, Yamochi T, Makino R, Kaneko K, Yamamoto T, Nozawa H, et al. Molecular differences between sporadic serrated and conventional colorectal adenomas. Clin Cancer Res 2004; 10:3082-3090.
13. Sawyer EJ, Cerar A, Hanby AM, Gorman P, Arends M, Talbot IC, et al. Molecular characteristics of serrated adenomas of the colorectum. Gut 2002; 51:200-206.
14. Capella G, Cronauer-Mitra S, Peinado MA, Perucho M. Frequency and spectrum of mutations at codons 12 and 13 of the C-K-ras gene in human tumours. Environ Health Perspect 1991; 93:125-131.
15. Ulvik A, Aarskog NK, Øgreid D. Detection and identification of Ki-ras exon 1 mutations by minigel single-strand conformation polymorphism. Anal Biochem 1995; 232:137-138.
16. Imperiale TF, Ransohoff DF, Itzkowitz SH, Turnbull BA, Ross ME. Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population. N Engl J Med 2004; 351:2704-2714.
17. Rhodes JM. Colorectal cancer screening in the UK: joint position statement by the British Society of Gastroenterology, The Royal College of Physicians, and the Association of Coloproctology of Great Britain and Ireland. Gut 2000; 46:746-748.
18. Song K, Fendrick AM, Ladabaum U. Fecal DNA testing compared with conventional colorectal cancer screening methods: a decision analysis. Gastroenterology 2004; 126:1270-1279.