Corticosteroids, 11β-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus

Journal of Neuroendocrinology

Volumn 19, Issue 8, 2007, Pages 614-620

  Sinclair, A J ^a,b   Onyimba, C U ^b   Khosla, P ^b   Vijapurapu, N ^b   Tomlinson, J W ^b   Burdon, M A ^a,b   Stewart, P M ^b   Murray, P I ^b   Walker, E A ^b   Rauz, S ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

11 hydroxysteroid dehydrogenase; Cerebrospinal fluid; Choroid plexus; Cortisol; Glucocorticoids

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTEROID; GLUCOCORTICOID RECEPTOR ALPHA; GLYCYRRHETINIC ACID; HYDROCORTISONE; MESSENGER RNA; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; ISOENZYME;

ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CEREBROSPINAL FLUID ANALYSIS; CHOROID PLEXUS; CILIARY BODY EPITHELIUM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLANT; FEMALE; HYDROCORTISONE RELEASE; IMMUNOLOCALIZATION; NEUROENDOCRINE DISEASE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; SECRETORY CELL; ANIMAL; CEREBROSPINAL FLUID; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADRENAL CORTEX HORMONES; ANIMALS; CHOROID PLEXUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HYDROCORTISONE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34447546532     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2007.01569.x     Document Type: Article

References (48)

1. Yau JL, Noble J, Kenyon CJ, Hibberd C, Kotelevtsev Y, Mullins JJ, Seckl JR. Lack of tissue glucocorticoid reactivation in 11beta-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proc Natl Acad Sci USA 2001; 98: 4716-4721.
2. Swaab DF, Bao AM, Lucassen PJ. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 2005; 4: 141-194.
3. Holmes MC, Seckl JR. The role of 11beta-hydroxysteroid dehydrogenases in the brain. Mol Cell Endocrinol 2006; 248: 9-14.
4. Holmes MC, Sangra M, French KL, Whittle IR, Paterson J, Mullins JJ, Seckl JR. 11beta-hydroxysteroid dehydrogenase type 2 protects the neonatal cerebellum from deleterious effects of glucocorticoids. Neuroscience 2006; 137: 865-873.
5. Sellebjerg F, Christiansen M, Jensen J, Frederiksen JL. Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis. Eur J Neurol 2000; 7: 281-289.
6. Huitinga I, Erkut ZA, van Beurden D, Swaab DF. The hypothalamo-pituitary-adrenal axis in multiple sclerosis. Ann NY Acad Sci 2003; 992: 118-128.
7. Miller TP, Taylor J, Rogerson S, Mauricio M, Kennedy Q, Schatzberg A, Tinklenberg J, Yesavage J. Cognitive and noncognitive symptoms in dementia patients: Relationship to cortisol and dehydroepiandrosterone. Int Psychogeriatr 1998; 10: 85-96.
8. Hoogendijk WJ, Meynen G, Endert E, Hofman MA, Swaab DF. Increased cerebrospinal fluid cortisol level in Alzheimer's disease is not related to depression. Neurobiol Aging 2005; 27: 780e1-780e2.
9. Lupien SJ, Nair NP, Briere S, Maheu F, Tu MT, Lemay M, McEwen BS, Meaney MJ. Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev Neurosci 1999; 10: 117-139.
10. Gerner RH, Wilkins JN. CSF cortisol in affective illness. Psychiatr Med 1985; 3: 33-40.
11. Stewart PM, Krozowski ZS. 11beta-hydroxysteroid dehydrogenase. Vitam Horm 1999; 57: 249-324.
12. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, Hewison M, Stewart PM. 11beta-hydroxysteroid dehydrogenase type 1: A tissue-specific regulator of glucocorticoid response. Endocr Rev 2004; 25: 831-866.
13. Funder JW, Pearce PT, Smith R, Smith AI. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 1988; 242: 583-585.
14. Rauz S, Walker EA, Shackleton CH, Hewison M, Murray PI, Stewart PM. Expression and putative role of 11 beta-hydroxysteroid dehydrogenase isozymes within the human eye. Invest Ophthalmol Vis Sci 2001; 42: 2037-2042.
15. Rauz S, Walker EA, Murray PI, Stewart PM. Expression and distribution of the serum and glucocorticoid regulated kinase and the epithelial sodium channel subunits in the human cornea. Exp Eye Res 2003; 77: 101-108.
16. Rauz S, Walker EA, Hughes SV, Coca-Prados M, Hewison M, Murray PI, Stewart PM. Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium. Invest Ophthalmol Vis Sci 2003; 44: 1643-1651.
17. Rauz S, Cheung CM, Wood PJ, Coca-Prados M, Walker EA, Murray PI, Stewart PM. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension. Q J Med 2003; 96: 481-490.
18. Onyimba CU, Vijapurapu N, Curnow SJ, Khosla P, Stewart PM, Murray PI, Walker EA, Rauz S. Characterisation of the prereceptor regulation of glucocorticoids in the anterior segment of the rabbit eye. J Endocrinol 2006; 190: 483-493.
19. Kostopoulos V, Douzinas EE, Kypriades EM, Pappas YZ. A new method for the early diagnosis of brain edema/brain swelling. An experimental study in rabbits. J Biomech 2006; 39: 2958-2965.
20. Artru AA, Momota T. Rate of CSF formation and resistance to reabsorption of CSF during sevoflurane or remifentanil in rabbits. J Neurosurg Anesthesiol 2000; 12: 37-43.
21. Uhl E, Wrba E, Nehring V, Chang RC, Baethmann A, Reulen HJ. Technical note: A new model for quantitative analysis of brain oedema resolution into the ventricles and the subarachnoid space. Acta Neurochir (Wien) 1999; 141: 89-92.
22. Senay LC Jr, Tolbert DL. Effect of arginine vasopressin, acetazolamide, and angiotensin II on CSF pressure at simulated altitude. Aviat Space Environ Med 1984; 55: 370-376.
23. Taplu A, Gokmen N, Erbayraktar S, Sade B, Erkan N, Karadibak K, Arkan A. Effects of pressure- and volume-controlled inverse ratio ventilation on haemodynamic variables, intracranial pressure and cerebral perfusion pressure in rabbits: A model of subarachnoid haemorrhage under isoflurane anaesthesia. Eur J Anaesthesiol 2003; 20: 690-696.
24. Greene CS, Jr Lorenzo G, Hornig, Welch K. The lowering of cerebral spinal fluid and brain interstitial pressure of preterm and term rabbits by furosemide. Z Kinderchir 1985; 40 (Suppl. 1): 5-8.
25. Ricketts ML, Verhaeg JM, Bujalska I, Howie AJ, Rainey WE, Stewart PM. Immunohistochemical localization of type 1, 11beta-hydroxysteroid dehydrogenase in human tissues. J Clin Endocrinol Metab 1998; 83: 1325-1335.
26. Shimojo M, Ricketts ML, Petrelli MD, Moradi P, Johnson GD, Bradwell AR, Hewison M, Howie AJ, Stewart PM. Immunodetection of 11 beta-hydroxysteroid dehydrogenase type 2 in human mineralocorticoid target tissues: Evidence for nuclear localization. Endocrinology 1997; 138: 1305-1311.
27. Bujalska I, Shimojo M, Howie A, Stewart PM. Human 11-hydroxysteroid dehydrogenase: Studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue. Steroids 1997; 77: 77-82.
28. Bujalska IJ, Kumar S, Stewart PM. Does central obesity reflect 'Cushing's disease of the omentum'? Lancet 1997; 349: 1210-1213.
29. Onyimba CU, Vijapurapu N, Curnow JS, Khosla P, Stewart PM, Murray PI, Walker EA, Rauz S. Characterisation of the prereceptor regulation of glucocorticoids in the anterior segment of the rabbit eye. J Endocrinol 2006; 190: 483-493.
30. +-ATPase catalytic polypeptide in mouse choroid plexus. J Histochem Cytochem 1986; 34: 189-195.
31. Speake T, Whitwell C, Kajita H, Majid A, Brown PD. Mechanisms of CSF secretion by the choroid plexus. Microsc Res Tech 2001; 52: 49-59.
32. Lakshmi V, Monder C. Purification and characterization of the corticosteroid 11 beta-dehydrogenase component of the rat liver 11 beta-hydroxysteroid dehydrogenase complex. Endocrinology 1988; 123: 2390-2398.
33. Wolf OT. HPA axis and memory. Best Pract Res Clin Endocrinol Metab 2003; 17: 287-299.
34. Arroyo A, Rosel P, Marron T. Cerebrospinal fluid: Postmortem biochemical study. J Clin Forensic Med 2005; 12: 153-156.
35. Guazzo EP, Kirkpatrick PJ, Goodyer IM, Shiers HM, Herbert J. Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: Relation to blood levels and the effects of age. J Clin Endocrinol Metab 1996; 81: 3951-3960.
36. Elenkov IJ. Glucocorticoids and the Th1/Th2 balance. Ann NY Acad Sci 2004; 1024: 138-146.
37. Marynick SP, Havens WW II, Ebert MH, Loriaux DL. Studies on the transfer of steroid hormones across the blood-cerebrospinal fluid barrier in the rhesus monkey. Endocrinology 1976; 99: 400-405.
38. Marynick SP, Smith GB, Ebert MH, Loriaux DL. Studies on the transfer of steroid hormones across the blood-cerebrospinal fluid barrier in the rhesus monkey. II. Endocrinology 1977; 101: 562-567.
39. Poisson M, Pertuiset BF, Moguilewsky M, Magdelenat H, Martin PM. [Steroid receptors in the central nervous system. Implications in neurology]. Rev Neurol (Paris) 1984; 140: 233-248.
40. Nishi M, Kawata M. Brain corticosteroid receptor dynamics and trafficking: Implications from live cell imaging. Neuroscientist 2006; 12: 119-133.
41. Harris HJ, Kotelevtsev Y, Mullins JJ, Seckl JR, Holmes MC. Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: Analysis of 11beta-HSD-1-deficient mice. Endocrinology 2001; 142: 114-120.
42. Baker DG, Ekhator NN, Kasckow JW, Dashevsky B, Horn PS, Bednarik L, Geracioti TD, Jr. Higher levels of basal serial CSF cortisol in combat veterans with posttraumatic stress disorder. Am J Psychiatry 2005; 162: 992-994.
43. Ueda K, Okamura N, Hirai M, Tanigawara Y, Saeki T, Kioka N, Komano T, Hori R. Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. J Biol Chem 1992; 267: 24248-24252.
44. Karssen AM, Meijer OC, van der Sandt IC, Lucassen PJ, de Lange EC, de Boer AG, de Kloet ER. Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain. Endocrinology 2001; 142: 2686-2694.
45. Kling MA, DeBellis MD, O'Rourke DK, Listwak SJ, Geracioti Jr TD, McCutcheon IE, Kalogeras KT, Oldfield EH, Gold PW. Diurnal variation of cerebrospinal fluid immunoreactive corticotropin-releasing hormone levels in healthy volunteers. J Clin Endocrinol Metab 1994; 79: 233-239.
46. Parry BL, Javeed S, Laughlin GA, Hauger R, Clopton P. Cortisol circadian rhythms during the menstrual cycle and with sleep deprivation in premenstrual dysphoric disorder and normal control subjects. Biol Psychiatry 2000; 48: 920-931.
47. Laughlin GA, Barrett-Connor E. Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: The Rancho Bernardo Study. J Clin Endocrinol Metab 2000; 85: 3561-3568.
48. Van Cauter E, Leproult R, Kupfer DJ. Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol. J Clin Endocrinol Metab 1996; 81: 2468-2473.