Selective amino acid substitutions convert the creatine transporter to a γ-aminobutyric acid transporter

Journal of Biological Chemistry

Volumn 282, Issue 21, 2007, Pages 15528-15533

  Dodd, Joanna R ^a   Christie, David L ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTIONS; AMINOBUTYRIC ACIDS; CREATINE TRANSPORTER (CRT); GAMMA AMINOBUTYRIC ACID (GABA);

BINDING SITES; ENZYME ACTIVITY; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; SUBSTITUTION REACTIONS; SUBSTRATES;

AMINO ACIDS;

4 AMINOBUTYRIC ACID; AMINO ACID; AMINO ACID TRANSPORTER; CREATINE; NEUROTRANSMITTER; NIPECOTIC ACID; SODIUM; 4 AMINOBUTYRIC ACID CARRIER; CARRIER PROTEIN; CREATINE TRANSPORTER; NIPECOTIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; BINDING SITE; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPLASM; DIFFUSION; ENZYME SPECIFICITY; MUTATION; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SENSITIVITY ANALYSIS; ACTIVE TRANSPORT; ANIMAL; CATTLE; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; GENETICS; METABOLISM; MISSENSE MUTATION; MOUSE; RAT; SEQUENCE HOMOLOGY;

EUKARYOTA; PROKARYOTA;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CATTLE; CERCOPITHECUS AETHIOPS; COS CELLS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MODELS, MOLECULAR; MUTATION, MISSENSE; NIPECOTIC ACIDS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 34447526785     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611705200     Document Type: Article

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