Zfrp8, the Drosophila ortholog of PDCD2, functions in lymph gland development and controls cell proliferation

Development

Volumn 134, Issue 13, 2007, Pages 2387-2396

  Minakhina, Svetlana ^a   Druzhinina, Marina ^a   Steward, Ruth ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Centrosome; Drosophila hematopoiesis; Lymph gland hyperplasia

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 27; CYCLIN B; GAMMA TUBULIN; GENE PRODUCT; PROTEIN CDC27; PROTEIN DGRIP91; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN RP 8;

ANIMAL CELL; ARTICLE; BLOOD CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; GENE INTERACTION; HEMATOPOIESIS; LYMPH NODE HYPERPLASIA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CENTROSOME; CYCLIN A; CYCLIN B; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HEMOCYTES; LYMPH NODES; MUTATION; PHENOTYPE; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EUKARYOTA;

EID: 34447515733     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.003616     Document Type: Article

References (55)

1. Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P., Nigg, E. A. and Mann, M. (2003). Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426, 570-574.
2. Ansieau, S. and Leutz, A. (2002). The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif. J. Biol. Chem. 277, 4906-4910.
3. Asha, H., Nagy, I., Kovacs, G., Stetson, D., Ando, I. and Dearolf, C. R. (2003). Analysis of Ras-induced overproliferation in Drosophila hemocytes. Genetics 163, 203-215.
4. Barbosa, V., Yamamoto, R. R., Henderson, D. S. and Glover, D. M. (2000). Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization. Genes Dev. 14, 3126-3139.
5. Chen, Q., Qian, K. and Yan, C. (2005). Cloning of cDNAs with PDCD2(C) domain and their expressions during apoptosis of HEK293T cells. Mol. Cell. Biochem. 280, 185-191.
6. Chew, S. K., Akdemir, F., Chen, P., Lu, W. J., Mills, K., Daish, T., Kumar S., Rodriguez, A. and Abrams, J. M. (2004). The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila. Dev. Cell 7, 897-907.
7. Chiu, H. and Govind, S. (2002). Natural infection of D. melanogaster by virulent parasitic wasps induces apoptotic depletion of hematopoietic precursors. Cell Death Differ. 9, 1379-1381.
8. Colombie, N., Verollet, C., Sampaio, P., Moisand, A., Sunkel, C., Bourbon, H. M., Wright, M. and Raynaud-Messina, B. (2006). The Drosophila gamma-tubulin small complex subunit Dgrip84 is required for structural and functional integrity of the spindle apparatus. Mol. Biol. Cell 17, 272-282.
9. Daga, A., Karlovich, C. A., Dumstrei, K. and Banerjee, U. (1996). Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1. Genes Dev. 10, 1194-1205.
10. Debec, A. and Montmory, C. (1992). Cyclin B is associated with centrosomes in Drosophila mitotic cells. Biol. Cell 75, 121-126.
11. Doxsey, S., Zimmerman, W. and Mikule, K. (2005). Centrosome control of the cell cycle. Trends Cell Biol. 15, 303-311.
12. Evans, C. J., Hartenstein, V. and Banerjee, U. (2003). Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev. Cell 5, 673-690.
13. Fan, C. W., Chan, C. C., Chao, C. C., Fan, H. A., Sheu, D. L. and Chan, E. C. (2004). Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line. Scand. J. Gastroenterol. 39, 464-469.
14. Fujiwara, Y., Chang, A. N., Williams, A. M. and Orkin, S. H. (2004). Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 103, 583-585.
15. Govind, S. (1996). Rel signalling pathway and the melanotic tumour phenotype of Drosophila. Biochem. Soc. Trans. 24, 39-44.
16. Gross, C. T. and McGinnis, W. (1996). DEAF-1, a novel protein that binds an essential region in a Deformed response element. EMBO J. 15, 1961-1970.
17. Hartenstein, V. (2006). Blood cells and blood cell development in the animal kingdom. Annu. Rev. Cell Dev. Biol. 22, 677-712.
18. Holz, A., Bossinger, B., Strasser, T., Janning, W. and Klapper, R. (2003). The two origins of hemocytes in Drosophila. Development 130, 4955-4962.
19. Hsu, L. C. and White, R. L. (1998). BRCA1 is associated with the centrosome during mitosis. Proc. Natl. Acad. Sci. USA 95, 12983-12988.
20. Huang, J. and Raff, J. W. (1999). The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells. EMBO J. 18, 2184-2195.
21. Ibanez, V., Sharma, A., Buonamici, S., Verma, A., Kalakonda, S., Wang, J., Kadkol, S. and Saunthararajah, Y. (2004). AML1-ETO decreases ETO-2 (MTG 16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation. Cancer Res. 64, 4547-4554.
22. Jackman, M., Lindon, C., Nigg, E. A. and Pines, J. (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat. Cell Biol. 5, 143-148.
23. Jensik, P. J., Huggenvik, J. I. and Collard, M. W. (2004). Identification of a nuclear export signal and protein interaction domains in deformed epidermal autoregulatory factor-1 (DEAF-1). J. Biol. Chem. 279, 32692-32699.
24. Jung, S. H., Evans, C. J., Uemura, C. and Banerjee, U. (2005). The Drosophila lymph gland as a developmental model of hematopoiesis. Development 132, 2521-2533.
25. Kawaguchi, S. and Zheng, Y. (2004). Characterization of a Drosophila centrosome protein CP309 that shares homology with Kendrin and CG-NAP. Mol. Biol. Cell 15, 37-45.
26. Kawakami, T., Furukawa, Y., Sudo, K., Saito, H., Takami, S., Takahashi, E. and Nakamura, Y. (1995). Isolation and mapping of a human gene (PDCD2) that is highly homologous to Rp8, a rat gene associated with programmed cell death. Cytogenet. Cell Genet. 71, 41-43.
27. Kramer, A., Mailand, N., Lukas, C., Syljuasen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. and Lukas, J. (2004). Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat. Cell Biol. 6, 884-891.
28. Krzemien, J., Dubois, L., Makki, R., Meister, M., Vincent, A. and Crozatier, M. (2007). Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre. Nature 446, 325-328.
29. Kurucz, E., Zettervall, C. J., Sinka, R., Vilmos, P., Pivarcsi, A., Ekengren, S. Hegedus, Z., Ando, I. and Hultmark, D. (2003). Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila. Proc. Natl. Acad. Sci. USA 100, 2622-2627.
30. Lanot, R., Zachary, D., Holder, F. and Meister, M. (2001). Postembryonic hematopoiesis in Drosophila. Dev. Biol. 230, 243-257.
31. Lavine, M. D. and Strand, M. R. (2002). Insect hemocytes and their role in immunity. Insect Biochem. Mol. Biol. 32, 1295-1309.
32. Lebestky, T., Jung, S. H. and Banerjee, U. (2003). A Serrate-expressing signaling center controls Drosophila hematopoiesis. Genes Dev. 17, 348-353.
33. Luo, H., Rose, P. E., Roberts, T. M. and Dearolf, C. R. (2002). The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila. Mol. Genet. Genomics 267, 57-63.
34. Lutterbach, B., Sun, D., Schuetz, J. and Hiebert, S. W. (1998). The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein. Mol. Cell. Biol. 18, 3604-3611.
35. Mahajan, S. S. and Wilson, A. C. (2000). Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP. Mol. Cell. Biol. 20, 919-928.
36. Mandal, L., Banerjee, U. and Hartenstein, V. (2004). Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm. Nat. Genet. 36, 1019-1023.
37. Mandal, L, Martinez-Agosto, J. A., Evans, C. J., Hartenstein, V. and Banerjee, U. (2007). A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. Nature 446, 320-324.
38. Meister, M. (2004). Blood cells of Drosophila: cell lineages and role in host defence. Curr. Opin. Immunol. 16, 10-15.
39. Milhola, O., Forejt, J. and Trachtulec, Z. (2007). Conserved alternative and antisense transcripts at the programmed cell death 2 locus. BMC Genomics 8, 20.
40. Minakhina, S. and Steward, R. (2006). Melanotic mutants in Drosophila: pathways and phenotypes. Genetics 174, 253-263.
41. Minakhina, S., Yang, J. and Steward, R. (2003). Tamo selectively modulates nuclear import in Drosophila. Genes Cells 8, 299-310.
42. Oegema, K., Wiese, C., Martin, O. C., Milligan, R. A., Iwamatsu, A., Mitchison, T. J. and Zheng, Y. (1999). Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules. J. Cell Biol. 144, 721-733.
43. Okuda, T., Nishimura, M., Nakao, M. and Fujita, Y. (2001). RUNX1/ AML1: a central player in hematopoiesis. Int. J. Hematol. 74, 252-257.
44. Orkin, S. H. (2000). Diversification of haematopoietic stem cells to specific lineages. Nat. Rev. Genet 1, 57-64.
45. Owens, G. P., Hahn, W. E. and Cohen, J. J. (1991). Identification of mRNAs associated with programmed cell death in immature thymocytes. Mol. Cell. Biol. 11, 4177-4188.
46. Parry, D. H. and O'Farrell, P. H. (2001). The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis. Curr. Biol. 11, 671-683.
47. Qiu, P., Pan, P. C. and Govind, S. (1998). A role for the Drosophila Toll/Cactus pathway, in larval hematopoiesis. Development 125, 1909-1920.
48. Rebhan, M., Chalifa-Caspi, V., Prilusky, J. and Lancet D. (1997). GeneCards: Encyclopedia for Genes, Proteins and Diseases. Rehovot, Israel: Weizmann Institute of Science, Bioinformatics Unit and Genome Center. http:/www.genecards.org/.
49. Rehorn, K. P., Thelen, H., Michelson, A. M. and Reuter, R. (1996). A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila. Development 122, 4023-4031.
50. Rizki, T. M. and Rizki, R. M. (1992). Lamellocyte differentiation in Drosophila larvae parasitized by Leptopilina. Dev. Comp. Immunol. 16, 103-110.
51. Sam, S., Leise, W. and Hoshizaki, D. K. (1996). The serpent gene is necessary for progression through the early stages of fat-body development. Mech. Dev. 60, 197-205.
52. Scarr, R. B. and Sharp, P. A. (2002). PDCD2 is a negative regulator of HCF-1 (C1). Oncogene 21, 5245-5254.
53. Sorrentino, R. P., Carton, Y. and Govind, S. (2002). Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated. Dev. Biol. 243, 65-80.
54. Steinemann, D., Gesk, S., Zhang, Y., Harder, L., Pilarsky, C., Hinzmann, B., Martin-Subero, J. I., Calasanz, M. J., Mungall, A., Rosenthal, A. et al. (2003). Identification of candidate tumor-suppressor genes in 6q27 by combined deletion mapping and electronic expression profiling in lymphoid neoplasms. Genes Chromosomes Cancer 37, 421-426.
55. Wakefield, J. G., Huang, J. Y. and Raff, J. W. (2000). Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos. Curr. Biol. 10, 1367-1370.