Induction of Fas (CD95/APO-1) ligand is essential for p53-dependent apoptosis in an in vitro renal carcinoma model system

Journal of Cancer Research and Clinical Oncology

Volumn 133, Issue 9, 2007, Pages 581-588

  Okazaki, Toshihiko ^b,c   Sakamuro, Daitoku ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; c Myc oncogene; Fas ligand; Fas receptor; p53 tumor suppressor; Renal carcinoma; Transactivation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; FAS ANTIGEN; FAS LIGAND; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; EPITHELIUM CELL; FLOW CYTOMETRY; GENE TRANSFER; IN VITRO STUDY; KIDNEY CARCINOMA; KIDNEY EPITHELIUM; NONHUMAN; NORTHERN BLOTTING; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; TEMPERATURE DEPENDENCE; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; VIRUS ONCOGENE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; FAS LIGAND PROTEIN; FLOW CYTOMETRY; KIDNEY NEOPLASMS; RATS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34447513709     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-007-0201-5     Document Type: Article

References (35)

1. Abdulkarim B, Sabri S, Deutsch E, Vaganay S, Marangoni E, Vainchenker W, Bongrand P, Busson P, Bourhis J (2000) Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells. Int J Cancer 86:229-237
2. Brunner T, Kasibhatla S, Pinkoski MJ, Frutschi C, Yoo NJ, Echeverri F, Mahboubi A, Green DR (2000) Expression of Fas ligand in activated T cells is regulated by c-Myc. J Biol Chem 275:9767-9772
3. Caricchio R, Reap EA, Cohen PL (1998) Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis. J Immunol 161:241-251
4. Chow WA, Fang JJ, Yee JK (2000) The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells. J Immunol 164:3512-3518
5. Debbas M, White E (1993) Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev 7:546-554
6. el-Deiry WS, Tokino, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825
7. Dubrez L, Savoy I, Hamman A, Solary E (1996) Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways. EMBO J 15:5504-5512
8. Faris M, Latinis KM, Kempiak SJ, Koretzky GA, Nel A (1998) Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol Cell Biol 18:5414-5424
9. Fukazawa T, Fujiwara T, Morimoto Y, Shao J, Nishizaki M, Kadowaki Y, Hizuta A, Owen-Schaub LB, Roth JA, Tanaka N (1999) Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cells. Oncogene 18:2189-2199
10. Gutierrez-Steil C, Wrone-Smith T, Sun X, Krueger JG, Coven T, Nickoloff BJ (1998) Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L). J Clin Invest 101:33-39
11. Hill LL, Ouhtit A, Loughlin SM, Kripke ML, Ananthaswamy HN, Owen-Schaub LB (1999) Fas ligand: a sensor for DNA damage critical in skin cancer etiology. Science 285:898-900
12. Hueber AO, Zornig M, Lyon D, Suda T, Nagata S, Evan GI (1997) Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis. Science 278:1305-1309
13. Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A, Green DR (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell 1:543-551
14. Kavurma MM, Khachigian LM (2003) Signaling and transcriptional control of Fas ligand gene expression. Cell Death Differ 10:36-44
15. Kirchhoff S, Sebens T, Baumann S, Krueger A, Zawatzky R, Li-Weber M, Meinl E, Neipel F, Fleckenstein B, Krammer PH (2002) Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter. J Immunol 168:1226-1234
16. Leverkus M, Yaar M, Gilchrest BA (1997) Fas/Fas ligand interaction contributes to UV-induced apoptosis in human keratinocytes. Exp Cell Res 232:255-262
17. Li H, Zhu H, Xu CJ, Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94:491-501
18. Lin P, Bush JA, Cheung KJ Jr, Li G (2002) Tissue-specific regulation of Fas/APO-1/CD95 expression by p53. Int J Oncol 21:261-264
19. Liu G, Xia T, Chen X (2003) The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein. J Biol Chem 278:17557-17565
20. Martinez J, Georgoff I, Martinez J, Levine AJ (1991) Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev 5:151-159
21. Michalovitz D, Halevy O, Oren M (1990) Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671-680
22. Milner J, Medcalf EA (1990) Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135. J Mol Biol 216:481-484
23. Muller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer PH, Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 99:403-413
24. Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedman SL, Galle PR, Stremmel W, Oren M, Krammer PH (1998) p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 188:2033-2045
25. Nagata S (1999) Fas ligand-induced apoptosis. Annu Rev Genet 33:29-55
26. Petak I, Tillman DM, Houghton JA (2000) p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines. Clin Cancer Res 6:4432-4441
27. Pinkoski MJ, Green DR (1999) Fas ligand, death gene. Cell Death Differ 6:1174-1181
28. Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (1997) A model for p53-induced apoptosis. Nature 389:300-305
29. Reinke V, Lozano G (1997) The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo. Oncogene 15:1527-1534
30. Sakamuro D, Eviner V, Elliott KJ, Showe L, White E, Prendergast GC (1995) c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms. Oncogene 11:2411-2418
31. Sakamuro D, Sabbatini P, White E, Prendergast GC (1997) The poly-proline region of p53 is required to activate apoptosis but not growth arrest. Oncogene 15:887-898
32. Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, Ariyasu T, Tachi M, Kasuga M (1995) Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells. Oncogene 11:1939-1946
33. Venot C, Maratrat M, Dureuil C, Conseiller E, Bracco L, Debussche L (1998) The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression, EMBO J 17:4668-4679
34. Wiener Z, Ontsouka EC, Jakob S, Torgler R, Falus A, Mueller C, Brunner T (2004) Synergistic induction of the Fas (CD95) ligand promoter by Max and NF-kappaB in human non-small lung cancer cells. Exp Cell Res 299:227-235
35. Zimmermann KC, Bonzon C, Green DR (2001) The machinery of programmed cell death. Pharmacol Ther 92:57-70